Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 VEGF signaling pathway 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
2 VEGF signaling pathway 💬
 [1] KDR 💬 D03218 💬 Axitinib [1] 34 💬
3 VEGF signaling pathway 💬
 [1] KDR 💬 D10062 💬 Cabozantinib [1] 34 💬
4 VEGF signaling pathway 💬
 [1] KDR 💬 D08881 💬 Cediranib [1] 34 💬
5 VEGF signaling pathway 💬
 [1] KDR 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
6 VEGF signaling pathway 💬
 [1] KDR 💬 D08552 💬 Sunitinib [2] 28, 34 💬
7 VEGF signaling pathway 💬
 [1] KDR 💬 D11772 💬 Tesevatinib [1] 67 💬
8 VEGF signaling pathway 💬
 [2] KDR, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
9 VEGF signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
10 VEGF signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
11 VEGF signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
12 VEGF signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
13 VEGF signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
14 VEGF signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
15 VEGF signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
16 VEGF signaling pathway 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
17 VEGF signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
18 VEGF signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
19 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
20 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
21 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
22 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
23 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
24 VEGF signaling pathway 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
25 VEGF signaling pathway 💬
 [1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
26 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
27 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
28 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
29 VEGF signaling pathway 💬
 [1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
30 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
31 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
32 VEGF signaling pathway 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
33 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
34 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
35 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
36 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
37 VEGF signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
38 VEGF signaling pathway 💬
 [1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
39 VEGF signaling pathway 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
40 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
41 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
42 VEGF signaling pathway 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
43 VEGF signaling pathway 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
44 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
45 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
46 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
47 VEGF signaling pathway 💬
 [1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
48 VEGF signaling pathway 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
49 VEGF signaling pathway 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
50 VEGF signaling pathway 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
51 VEGF signaling pathway 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
52 VEGF signaling pathway 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
53 VEGF signaling pathway 💬
 [1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
54 VEGF signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
55 VEGF signaling pathway 💬
 [1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬