Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
2	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
3	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
4	Toll-like receptor signaling pathway 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271 ...
5	Toll-like receptor signaling pathway 💬	[2] CD80, CD86 💬	D03222 💬	Belatacept	[1] 46 💬
6	Toll-like receptor signaling pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09662 💬	Rontalizumab	[1] 49 💬
7	Toll-like receptor signaling pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09668 💬	Sifalimumab	[1] 49 💬
8	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D11082 💬	Anifrolumab	[3] 46, 49, 53 💬
9	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D03305 💬	Interferon alfa	[6] 13, 25, 26, 28, 56, 96 💬
10	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D00745 💬	Interferon alfa-2a	[1] 56 💬

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