Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Artesunate [1] Artesunate[1] D02482 --[8] 18, 46, 53, 66, 96, 97, 215, 271
2 Baclofen [2] Baclofen; Kemstro[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[7] 2, 10, 13, 18, 65, 149, 206
3 Bupropion [2] Bupropion; Bupropion Hydrochloride[3] D00817 ,
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
4 Butylphthalide [1] Butylphthalide---[4] 2, 6, 18, 22
5 Calcitriol [1] Calcitriol[1] D00129 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
6 Carbonate ion [1] Carbonate---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
7 Citalopram [1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
8 Deferiprone [2] DEFERIPRONE; Ferriprox[1] D07416 --[6] 2, 6, 18, 120, 122, 233
9 Erythropoietin [4] Epoetin alfa; Epoetin beta; Erythropoietin; Neorecormon[1] D03231 [1] EPOR 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[10] 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
10 Etravirine [3] ETRAVIRINA; Etravirine; INTELENCE[1] D04112 --[1] 18
11 Flumazenil [1] Flumazenil[1] D00697 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206
12 Ginkgo biloba [3] Ginkgo; Ginkgo biloba; Tanakan---[5] 6, 13, 18, 47, 90
13 Idebenone [2] IDEBENONE; Raxone[1] D01750 --[6] 6, 8, 13, 18, 113, 302
14 Interferon Gamma [1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326
15 Interferon gamma-1b [2] ACTIMMUNE; INTERFERON GAMMA-1B[1] D00747 [2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
16 Iron [1] Iron---[6] 18, 96, 97, 238, 254, 284
17 Lenograstim [2] G-CSF; LENOGRASTIM[1] D03247 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
18 Lithium carbonate [2] Lithium; Lithium Carbonate[1] D00801 --[6] 2, 13, 17, 18, 19, 127
19 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
20 Nicotinamide [4] Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
21 Nicotinamide riboside [1] Nicotinamide riboside---[4] 2, 6, 18, 191
22 Omaveloxolone [1] Omaveloxolone[1] D10964 [1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18
23 Resveratrol [1] Resveratrol---[6] 2, 8, 18, 89, 113, 299
24 Riluzole [2] Rilutek; Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
25 Rosuvastatin [3] Crestor; Rosuvastatin; Rosuvastatin calcium[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
26 TAK-831 [1] TAK-831---[1] 18
27 Trehalose [2] Cabaletta; Trehalose---[3] 2, 18, 113
28 Ubidecarenone [3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[13] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
29 Varenicline [2] Champix; Varenicline[1] D08669 [2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[2] 6, 18
30 Vatiquinone [1] VATIQUINONE[1] D10407 --[2] 18, 21