Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Amphotericin B
(Synonym: Amphotec 100 mg)		[2] ABELCET; Amphotericin B[1] D00203 --[1] 299
2 Ascorbic acid
(Synonym: Vitamin C 100 Mg Orange Chewable)		[4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C[1] D00018 --[8] 10, 97, 192, 206, 210, 211, 212, 298
3 Atenolol
(Synonym: Riva-atenolol 100 mg)		[1] ATENOLOL[1] D00235 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
4 Carbamazepine
(Synonym: Tegretol Chewtabs 100 mg)		[1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[2] 13, 231
5 Carbidopa
(Synonym: Nu-levocarb - Tab 25 Mg/100 mg)		[7] CARBIDOPA; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] D00558 [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[9] 2, 4, 6, 13, 17, 90, 140, 164, 201
6 Celecoxib
(Synonym: Celecoxib 100 mg)		[2] Celebrex; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
7 Ciprofloxacin
(Synonym: Ciprofloxacin Tablets USP - 100 mg)		[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE[2] D00186 ,
D02216 		--[5] 2, 60, 96, 97, 299
8 Fenofibrate
(Synonym: Lipidil Supra 100 mg)		[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
9 Flurbiprofen
(Synonym: Ansaid Tablets 100 mg)		[1] Flurbiprofen[3] D00330 ,
D01475 ,
D02290 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
10 Hydrochlorothiazide
(Synonym: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg)		[2] Esidrix; HYDROCHLOROTHIAZIDE[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
11 Leflunomide
(Synonym: Arava 100 mg)		[3] ARAVA; Leflunomide; Leflunomidum[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
12 Levodopa
(Synonym: Nu-levocarb - Tab 25 Mg/100 mg)		[8] DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 2, 4, 6, 17, 90, 140, 164, 201
13 Losartan
(Synonym: LOSARTAN POTASSIUM 100 mg)		[3] Cozaar; Losartan; LOSARTAN POTASSIUM[2] D00357 (Name: LOSARTAN POTASSIUM TABLETS, 100 MG),
D08146 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
14 Meperidine
(Synonym: Demerol 100 mg/ml)		[1] Pethidine[2] D01383 ,
D08343 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 298
15 Metoprolol
(Synonym: Betaloc Tab 100 mg)		[2] Metoprolol; METOPROLOL SUCCINATE[3] D00601 ,
D02358 ,
D05011 		[1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226
16 Morphine
(Synonym: PMS-morphine Sulfate SR 100 mg)		[2] Morphine; MORPHINE SULFATE[3] D00842 ,
D02271 ,
D08233 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298
17 Niacin
(Synonym: Niacin 100 Mg Tablets)		[2] Niacin; Nicotinic acid[1] D00049 --[4] 6, 78, 79, 265
18 Nicotinamide
(Synonym: Niacinamide 100 Mg Tablets)		[4] Ginseng; Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
19 Pyridoxine
(Synonym: Vitamin B6 100 Mg USP)		[2] Pyridoxine; Vitamin B6[2] D02179 ,
D08454 		--[5] 6, 93, 145, 206, 320
20 Riboflavin
(Synonym: Vitamin B2 100 mg)		[2] RIBOFLAVIN; Vitamin B2[3] D00050 ,
D01622 ,
D01913 		--[8] 13, 38, 46, 96, 97, 162, 168, 265
21 Spironolactone
(Synonym: Aldactone 100 mg)		[1] Spironolactone[1] D00443 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[7] 58, 67, 86, 113, 210, 218, 225
22 Theophylline
(Synonym: Theo-dur 100 mg)		[1] Theophylline[5] D00371 ,
D01712 ,
D02017 ,
D06103 ,
D06104 		[19] ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[24] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
23 Thiamine
(Synonym: Vitamine B1 100 Mg - Tablet)		[2] THIAMINE; Vitamin B1[1] D08580 --[5] 8, 13, 93, 145, 265
24 Tranexamic acid
(Synonym: Cyklokapron 100 mg/ml)		[1] Tranexamic acid[1] D01136 [1] PLG 💬[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[6] 46, 70, 215, 227, 288, 299
25 Ubidecarenone
(Synonym: Coenzyme Q10 100 mg)		[3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[13] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215