Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Dometuss-NR)		[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Amlodipine
(Synonym: Nra-amlodipine)		[1] Amlodipine[3] D00615 ,
D02914 ,
D07450 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
3 Atorvastatin
(Synonym: Nra-atorvastatin)		[3] Atorvastatin; Atorvastatin calcium; Lipitor[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
4 Azithromycin
(Synonym: Nra-azithromycin)		[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX[3] D02134 ,
D06390 ,
D07486 		--[6] 13, 84, 85, 96, 228, 299
5 Biotin
(Synonym: Nrg Plus Liq)		[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7[1] D00029 --[5] 2, 8, 10, 13, 20
6 Celecoxib
(Synonym: Nra-celecoxib)		[2] CELEBREX; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
7 Cetirizine
(Synonym: Nra-cetirizine)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[2] D00664 ,
D07662 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
8 Chlorpheniramine
(Synonym: Dometuss-NR)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
9 Cholecalciferol
(Synonym: Nrg Plus Liq)		[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
10 Choline
(Synonym: Nrg Plus Liq)		[1] Choline[1] D07690 --[4] 93, 171, 193, 299
11 Ciprofloxacin
(Synonym: Nra-ciprofloxacin)		[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE[2] D00186 ,
D02216 		--[5] 2, 60, 96, 97, 299
12 Citalopram
(Synonym: Nra-citalopram)		[1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
13 Clindamycin
(Synonym: Nra-clindamycin)		[2] Clindamycin; Dalacin C phosphate[4] D00277 ,
D01073 ,
D01990 ,
D02132 		--[2] 46, 299
14 Clopidogrel
(Synonym: Nra-clopidogrel)		[1] Clopidogrel[4] D00769 ,
D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[2] 49, 86
15 Cyanocobalamin
(Synonym: Nrg Plus Liq)		[2] Cianocobalamina; Vitamin B12[4] D00166 ,
D03615 ,
D03616 ,
D03617 		--[5] 6, 13, 201, 229, 299
16 Dextromethorphan
(Synonym: Guaifenesin-DM Nr)		[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
17 Duloxetine
(Synonym: Nra-duloxetine)		[3] Cymbalta; DULOXETINE; Duloxetine hydrochloride[2] D01179 ,
D07880 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13
18 Escitalopram
(Synonym: Nra-escitalopram)		[3] Citalopram; Escitalopram; Escitalopram oxalate[3] D02567 ,
D07704 ,
D07913 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
19 Ethanol
(Synonym: Nrl Pure Daily Hand Sanitizer)		[3] Alcohol; Ethanol; PREDNISONE[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
20 Ezetimibe
(Synonym: Nra-ezetimibe)		[2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
21 Fluoxetine
(Synonym: Nra-fluoxetine)		[5] Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[2] D00326 ,
D00823 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
22 Hydrochlorothiazide
(Synonym: Nra-olmesartan Hctz)		[2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
23 Hydroxychloroquine
(Synonym: Nra-hydroxychloroquine)		[3] Hydroxychloroquine; Hydroxychloroquine Sulfate; Plaquenil[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
24 Inositol
(Synonym: Nrg Plus Liq)		[1] Inositol[1] D08079 --[2] 96, 97
25 Lacosamide
(Synonym: Nra-lacosamide)		[1] Lacosamide[1] D07299 [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[3] 2, 46, 149
26 Letrozole
(Synonym: Nra-letrozole)		[1] Letrozole[1] D00964 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89
27 Levetiracetam
(Synonym: Nra-levetiracetam)		[2] KEPPRA; Levetiracetam[1] D00709 [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
28 Montelukast
(Synonym: Nra-montelukast)		[3] Montelukast; MONTELUKAST SODIUM; Singulair[2] D00529 ,
D08229 		[1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228
29 Nicotinamide
(Synonym: Nrg Plus Liq)		[4] Ginseng; Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
30 Omeprazole
(Synonym: Nra-omeprazole)		[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
31 Pantoprazole
(Synonym: Nra-pantoprazole)		[1] PANTOPRAZOLE[2] D02593 ,
D05353 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65
32 Paroxetine
(Synonym: Nra-paroxetine)		[1] Paroxetine[4] D02260 ,
D02362 ,
D05374 ,
D05375 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
33 Perindopril
(Synonym: Nra-perindopril)		[2] Coversyl; Perindopril[2] D00624 ,
D03753 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222
34 Phenylephrine
(Synonym: Dometuss-NR)		[1] Phenylephrine[2] D00511 ,
D08365 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
35 Pregabalin
(Synonym: Nra-pregabalin)		[2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
36 Pyridoxine
(Synonym: Nrg Plus Liq)		[2] Pyridoxine; Vitamin B6[2] D02179 ,
D08454 		--[5] 6, 93, 145, 206, 320
37 Quetiapine
(Synonym: Nra-quetiapine)		[2] Quetiapine; Seroquel[2] D00458 ,
D08456 		[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13
38 Ramipril
(Synonym: Nra-ramipril)		[1] RAMIPRIL[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
39 Rosuvastatin
(Synonym: Nra-rosuvastatin)		[3] Crestor; Rosuvastatin; Rosuvastatin calcium[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
40 Sertraline
(Synonym: Nra-sertraline)		[1] Sertraline[2] D00825 ,
D02360 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206
41 Sildenafil
(Synonym: Nra-sildenafil)		[6] Mysildecard; REVATIO; SILDENAFIL; SILDENAFIL CITRATE; SILDENAFILO; VIAGRA[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
42 Sodium fluoride
(Synonym: Nrg Apf)		[2] Beam; Sodium fluoride[1] D00943 --[1] 51
43 Tadalafil
(Synonym: Nra-tadalafil)		[4] Adcirca; Cialis; Tadalafil; TADALAFILO[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
44 Telmisartan
(Synonym: Nra-telmisartan Hctz)		[1] Telmisartan[1] D00627 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67
45 Thiamine
(Synonym: Nrg Plus Liq)		[2] Thiamine; Vitamin B1[1] D08580 --[5] 8, 13, 93, 145, 265
46 Tramadol
(Synonym: Nra-tramadol/acet)		[2] Tramadol; Ultracet[2] D01355 ,
D08623 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
47 Vitamin A
(Synonym: Nrg Plus Liq)		[1] Vitamin A[2] D00069 ,
D06543 		[2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90
48 Zolmitriptan
(Synonym: Nra-zolmitriptan)		[1] Zolmitriptan[1] D00415 [2] HTR1B,
HTR1D 💬		[4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6
49 Zopiclone
(Synonym: Nra-zopiclone)		[1] Zopiclone[1] D01372 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6