Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
3 IFNA1 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
4 IFNA1 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
5 IFNA2 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
6 IFNA2 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
7 IFNA4 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
8 IFNA4 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
9 IFNA5 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
10 IFNA5 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
11 IFNA6 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
12 IFNA6 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
13 IFNA7 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
14 IFNA7 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
15 IFNA8 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
16 IFNA8 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
17 IFNA10 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
18 IFNA10 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
19 IFNA13 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
20 IFNA13 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
21 IFNA14 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
22 IFNA14 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
23 IFNA16 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
24 IFNA16 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
25 IFNA17 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
26 IFNA17 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
27 IFNA21 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09662 Rontalizumab [1] 49
28 IFNA21 [3] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis D09668 Sifalimumab [1] 49
29 IL12A [6] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D09214 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
30 IL12B [6] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D09214 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
31 NFKB1 [15] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod [4] 46, 51, 53, 271
32 MAPK11 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
33 MAPK11 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
34 MAPK13 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
35 MAPK13 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
36 RELA [15] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent [1] 113
37 MAPK12 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
38 MAPK12 [15] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
39 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
40 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
41 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
42 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
43 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
44 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
45 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
46 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
47 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D05393 Pegsunercept [1] 46
48 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
49 TNF [15] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D09944 Ozoralizumab [1] 46