Isotretinoin ( DrugBank: Isotretinoin )

4 diseases

36. 表皮水疱症

臨床試験数 : 160 / 薬物数 : 195 - (DrugBank : 47) / 標的遺伝子数 : 50 - 標的パスウェイ数 : 124

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00014729 (ClinicalTrials.gov)	October 2000	10/4/2001	Phase I Study of Isotretinoin in Patients With Recessive Dystrophic Epidermolysis Bullosa		Epidermolysis Bullosa	Drug: isotretinoin	University of North Carolina	NULL	Completed	15 Years	N/A	Both	20	Phase 1	NULL

臨床試験数 : 13 / 薬物数 : 19 - (DrugBank : 8) / 標的遺伝子数 : 11 - 標的パスウェイ数 : 103

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02795143 (ClinicalTrials.gov)	November 2016	6/6/2016	Evaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot Study	Evaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot Study	Toxic Epidermal Necrolysis	Drug: Isotretinoin;Other: Placebo	Massachusetts General Hospital	NULL	Recruiting	18 Years	69 Years	Both	40	N/A	United States

臨床試験数 : 10 / 薬物数 : 18 - (DrugBank : 5) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00025012 (ClinicalTrials.gov)	June 1991	11/10/2001	Isotretinoin in Preventing Skin Cancer	Use Of Isotretinion For Prevention Of Skin Cancer In Patients With Xeroderma Pigmentosum Or Nevoid Basal Cell Carcinoma Syndrome	Melanoma (Skin);Non-melanomatous Skin Cancer	Drug: isotretinoin	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	NULL	Completed	2 Years	N/A	Both		N/A	United States

臨床試験数 : 36 / 薬物数 : 72 - (DrugBank : 21) / 標的遺伝子数 : 18 - 標的パスウェイ数 : 111

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04154293 (ClinicalTrials.gov)	December 3, 2019	1/11/2019	A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis	A Randomized, Parallel, Double-Blind, Vehicle Controlled Study to Evaluate the Safety and Efficacy of Two Concentrations of Topical TMB-001 for the Treatment of Congenital Ichthyosis	Congenital Ichthyosis	Drug: Isotretinoin;Other: Vehicle	Timber Pharmceuticals LLC	NULL	Completed	9 Years	N/A	All	34	Phase 2	United States;Australia