Ammonia ( DrugBank: Ammonia )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
86肺動脈性肺高血圧症1
88慢性血栓塞栓性肺高血圧症1
296胆道閉鎖症1

86. 肺動脈性肺高血圧症


臨床試験数 : 1,181 薬物数 : 701 - (DrugBank : 126) / 標的遺伝子数 : 105 - 標的パスウェイ数 : 192
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03344159
(ClinicalTrials.gov)
April 1, 201828/9/2017Spironolactone Therapy in Chronic Stable Right HF TrialSpironolactone Therapy in Chronic Stable Right HF TrialChronic Right-Sided Heart Failure;Pulmonary Arterial Hypertension;Pulmonary Hypertension, Primary, 2;Pulmonary Hypertension, Primary, 3;Pulmonary Hypertension, Primary, 4;Cardiomyopathy Right VentricularDrug: Spironolactone;Drug: Placebo;Radiation: PET/CT Scan: Two PET scans using 1. C-11 HED and 2. N-13 Ammonia or rubidium-82;Diagnostic Test: Cardiac MRI (Gadolinium enhanced)Ottawa Heart Institute Research CorporationNULLRecruiting18 YearsN/AAll30Phase 4Canada

88. 慢性血栓塞栓性肺高血圧症


臨床試験数 : 159 薬物数 : 118 - (DrugBank : 23) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 53
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02094001
(ClinicalTrials.gov)
May 201417/3/2014Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPHEvaluation of Right Ventricular Function and Metabolism Following Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension- Images of RioChronic Thromboembolic Pulmonary HypertensionRadiation: Cardiac PET imaging using F-18-FDG, N-13 ammonia( NH3)Ottawa Heart Institute Research CorporationBayerCompleted18 YearsN/AAll6Phase 2Canada

296. 胆道閉鎖症


臨床試験数 : 63 薬物数 : 65 - (DrugBank : 37) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 63
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1ChiCTR2100044533
2021-06-012021-03-23Multicenter study of non-invasive diagnostic scoring system for biliary atresiaMulticenter study of non-invasive diagnostic scoring system for biliary atresia Biliary atresiaGold Standard:Intraoperative cholangiography;Index test:Non-invasive diagnostic scoring system for biliary atresia (Biochemicaltests, blood routine, CRP, blood ammonia, AFP, hepatobiliary B ultrasound);Children's Hospital Affiliated to Zhejiang University Medical CollegeNULLRecruitingBothTarget condition:200;Difficult condition:0China