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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1A4250----4件: 93, 296, 297, 338
2Acetylcysteine1件: Acetylcysteine1件: D00221 --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
3Ammonia1件: Ammonia1件: D02916 --3件: 86, 88, 296
4BELIMUMAB1件: Belimumab1件: D03068 1件: TNFSF13B 💬4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300
5Bezafibrate1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
6Bicarbonate Ringer's solution----1件: 296
7Cefoperazone1件: Cefoperazone1件: D07645 --1件: 296
8Chloride1件: Chloride ion---29件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 271, 288, 296, 297, 299, 338
9Combination Product: high MCT formula----1件: 296
10Corticosteroids----10件: 41, 46, 49, 64, 97, 107, 164, 220, 296, 300
11Cysteine1件: Cysteine2件: D00026 ,
D02326 		--11件: 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
12Desflurane1件: Desflurane1件: D00546 --2件: 22, 296
13Desflurane anesthetics1件: Desflurane1件: D00546 --1件: 296
14Dexamethasone1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
15DIMETHYL FUMARATE1件: Dimethyl fumarate1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬4件: 13, 51, 86, 296
16Eicosapentaenoic acid1件: Icosapent1件: D08061 --6件: 49, 96, 97, 296, 297, 338
17Epadel----1件: 296
18Filgrastim1件: Filgrastim1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬28件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
19Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
20Granulocyte Colony-Stimulating Factor----1件: 296
21ICG Pulsion----1件: 296
22ICG-Pulsion 25mg----1件: 296
23Indocyanine green1件: Indocyanine green1件: D01342 --8件: 22, 46, 51, 96, 235, 278, 291, 296
24Intravenous immunoglobulin (IVIg)1件: Human immunoglobulin G---4件: 14, 17, 164, 296
25Lactated Ringer----1件: 296
26Lactobacillus casei1件: Lactobacillus casei1件: D04351 --3件: 6, 97, 296
27Lactobacillus casei rhamnosus (Lcr35)1件: Lactobacillus casei1件: D04351 --1件: 296
28Magnesium1件: Magnesium---19件: 3, 6, 11, 13, 15, 46, 64, 70, 93, 97, 166, 225, 235, 256, 284, 291, 296, 297, 298
29Magnesium gluconate2件: Magnesium,
Magnesium gluconate		1件: D04835 --2件: 296, 297
30Magnesium sulfate3件: Magnesium gluconate,
Magnesium sulfate,
Sulfate ion		2件: D01108 ,
D04835 		--3件: 11, 296, 297
31Maralixibat1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
32Maralixibat (formely SHP625 or LUM001)1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
33MARALIXIBAT CHLORIDE2件: Chloride ion,
Maralixibat		1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
34Maralixibat cloruro1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬2件: 296, 338
35MCT----2件: 6, 296
36MCT powder----1件: 296
37Meloxicam1件: Meloxicam1件: D00969 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296
38Methylprednisolone1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
39N-acetyl Cysteine1件: Cysteine2件: D00026 ,
D02326 		--7件: 13, 19, 34, 85, 88, 296, 310
40Neomycin1件: Neomycin1件: D08260 --3件: 96, 97, 296
41Normal Saline----18件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299
42Obeticholic Acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
43OCA----2件: 94, 296
44OCA 0.1 mg----1件: 296
45OCA 1.5mg----1件: 296
46OCA 5mg----1件: 296
47Ocaliva1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬2件: 93, 296
48Odevixibat1件: Odevixibat1件: D11716 1件: SLC10A2 💬1件: Bile secretion 💬3件: 296, 297, 338
49Oral Vancomycin1件: Vancomycin2件: D00212 ,
D00926 		--2件: 94, 296
50Other Crystalloid----1件: 296
51Pentoxifylline1件: Pentoxifylline1件: D00501 --10件: 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
52PREDNISOLONE1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬43件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
53Propanolol1件: Propranolol2件: D00483 ,
D08443 		3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 296
54PROPOFOL1件: Propofol1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬9件: 6, 21, 22, 34, 46, 70, 84, 98, 296
55Rifaximin1件: Rifaximin1件: D02554 --7件: 6, 65, 93, 96, 97, 99, 296
56Rituximab1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬49件: 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
57Rocuronium1件: Rocuronium1件: D00765 16件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB2,
CHRNB3,
CHRNB4 💬		15件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 296
58Sevoflurane1件: Sevoflurane1件: D00547 --7件: 6, 21, 22, 34, 98, 225, 296
59Sevoflurane anesthetics1件: Sevoflurane1件: D00547 --1件: 296
60Sulfate1件: Sulfate ion---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
61UDCA1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬6件: 46, 67, 93, 94, 97, 296
62Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation----2件: 93, 296
63Vancomycin1件: Vancomycin2件: D00212 ,
D00926 		--7件: 46, 70, 94, 96, 97, 296, 299
64VO4CX----1件: 296