DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 26 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CTLA4
💬
1. CTLA4
×
Name
Full Name
CTLA4
cytotoxic T-lymphocyte associated protein 4
4件:
Cell adhesion molecules
Cell adhesion molecules
,
T cell receptor signaling pathway
,
Autoimmune thyroid disease
,
Rheumatoid arthritis
4件:
Cell adhesion molecules
,
T cell receptor signaling pathway
,
Autoimmune thyroid disease
,
Rheumato
...
Ipilimumab
Ipilimumab
💬
1. CTLA4
×
Name
Other Names
Ipilimumab
Ipilimumab (USAN/INN)
Ipilimumab (genetical recombination) (JAN)
Yervoy (TN)
イピリムマブ
ヤーボイ
Ipilimumab
1件:
159
159
💬
1. CTLA4
×
告示番号
日本語名
英語名
159
色素性乾皮症
Xeroderma pigmentosum
2
CTLA4
💬
2. CTLA4
×
Name
Full Name
CTLA4
cytotoxic T-lymphocyte associated protein 4
4件:
Cell adhesion molecules
Cell adhesion molecules
,
T cell receptor signaling pathway
,
Autoimmune thyroid disease
,
Rheumatoid arthritis
4件:
Cell adhesion molecules
,
T cell receptor signaling pathway
,
Autoimmune thyroid disease
,
Rheumato
...
Tremelimumab
Tremelimumab
💬
2. CTLA4
×
Name
Other Names
Tremelimumab
Tremelimumab (USAN/INN)
Tremelimumab (genetical recombination) (JAN)
Tremelimumab-actl
CP 675206
Imjudo (TN)
トレメリムマブ
イジュド
Tremelimumab
1件:
96
96
💬
2. CTLA4
×
告示番号
日本語名
英語名
96
クローン病;回腸末端炎
Crohn disease
3
CD274
💬
3. CD274
×
Name
Full Name
CD274
CD274 molecule
2件:
Cell adhesion molecules
Cell adhesion molecules
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
Atezolizumab
Atezolizumab
💬
3. CD274
×
Name
Other Names
Atezolizumab
Atezolizumab (USAN/INN)
Atezolizumab (genetical recombination) (JAN)
Tecentriq (TN)
アテゾリズマブ
テセントリク
Atezolizumab
1件:
85
85
💬
3. CD274
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
4
CD274
💬
4. CD274
×
Name
Full Name
CD274
CD274 molecule
2件:
Cell adhesion molecules
Cell adhesion molecules
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
Durvalumab
Durvalumab
💬
4. CD274
×
Name
Other Names
Durvalumab
Durvalumab (USAN/INN)
Durvalumab (genetical recombination) (JAN)
Imfinzi (TN)
デュルバルマブ
イミフィンジ
Durvalumab
1件:
85
85
💬
4. CD274
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
5
ITGA4
💬
5. ITGA4
×
Name
Full Name
ITGA4
integrin subunit alpha 4
14件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Hematopoietic cell lineage
,
Leukocyte transendothelial migration
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Yersinia infection
,
Leishmaniasis
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
14件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
Firategrast
Firategrast
💬
5. ITGA4
×
Name
Other Names
Firategrast
Firategrast (USAN)
フィラテグラスト
Firategrast
1件:
13
13
💬
5. ITGA4
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
6
ITGA4
💬
6. ITGA4
×
Name
Full Name
ITGA4
integrin subunit alpha 4
14件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Hematopoietic cell lineage
,
Leukocyte transendothelial migration
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Yersinia infection
,
Leishmaniasis
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
14件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
Natalizumab
Natalizumab
💬
6. ITGA4
×
Name
Other Names
Natalizumab
Natalizumab (USAN/INN)
Natalizumab (genetical recombination) (JAN)
Tysabri (TN)
ナタリズマブ
タイサブリ
Natalizumab
6件:
13
13
,
15
,
25
,
46
,
63
,
96
💬
6. ITGA4
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
15
封入体筋炎
Inclusion body myositis
25
進行性多巣性白質脳症
Progressive multifocal leukoencephalopathy
46
悪性関節リウマチ
Malignant rheumatoid arthritis
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
96
クローン病;回腸末端炎
Crohn disease
7
ITGA4
💬
7. ITGA4
×
Name
Full Name
ITGA4
integrin subunit alpha 4
14件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Hematopoietic cell lineage
,
Leukocyte transendothelial migration
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Yersinia infection
,
Leishmaniasis
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
14件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
Vedolizumab
Vedolizumab
💬
7. ITGA4
×
Name
Other Names
Vedolizumab
Vedolizumab (USAN)
Vedolizumab (genetical recombination) (JAN)
Entyvio (TN)
ベドリズマブ
エンタイビオ
Vedolizumab
3件:
94
94
,
96
,
97
💬
7. ITGA4
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
8
ITGA4
💬
8. ITGA4
×
Name
Full Name
ITGA4
integrin subunit alpha 4
14件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Hematopoietic cell lineage
,
Leukocyte transendothelial migration
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Yersinia infection
,
Leishmaniasis
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
14件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
Abrilumab
Abrilumab
💬
8. ITGA4
×
Name
Other Names
Abrilumab
Abrilumab (USAN/INN)
アブリルマブ
Abrilumab
2件:
96
96
,
97
💬
8. ITGA4
×
告示番号
日本語名
英語名
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
9
ITGAL
💬
9. ITGAL
×
Name
Full Name
ITGAL
integrin subunit alpha L
12件:
Rap1 signaling pathway
Rap1 signaling pathway
,
Cell adhesion molecules
,
Neutrophil extracellular trap formation
,
Natural killer cell mediated cytotoxicity
,
Leukocyte transendothelial migration
,
Regulation of actin cytoskeleton
,
Malaria
,
Staphylococcus aureus infection
,
Human T-cell leukemia virus 1 infection
,
Epstein-Barr virus infection
,
Rheumatoid arthritis
,
Viral myocarditis
12件:
Rap1 signaling pathway
,
Cell adhesion molecules
,
Neutrophil extracellular trap formation
,
Natur
...
Efalizumab
Efalizumab
💬
9. ITGAL
×
Name
Other Names
Efalizumab
Efalizumab (USAN/INN)
Raptiva (TN)
エファリズマブ
Efalizumab
9件:
11
11
,
13
,
37
,
46
,
49
,
53
,
61
,
95
,
96
💬
9. ITGAL
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
37
膿疱性乾癬（汎発型）
Generalised pustular psoriasis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
53
シェーグレン症候群
Sjogren syndrome
61
自己免疫性溶血性貧血
Autoimmune hemolytic anemia
95
自己免疫性肝炎
Autoimmune hepatitis
96
クローン病;回腸末端炎
Crohn disease
10
ITGB7
💬
10. ITGB7
×
Name
Full Name
ITGB7
integrin subunit beta 7
11件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Human papillomavirus infection
,
Transcriptional misregulation in cancer
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
11件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
Vedolizumab
Vedolizumab
💬
10. ITGB7
×
Name
Other Names
Vedolizumab
Vedolizumab (USAN)
Vedolizumab (genetical recombination) (JAN)
Entyvio (TN)
ベドリズマブ
エンタイビオ
Vedolizumab
3件:
94
94
,
96
,
97
💬
10. ITGB7
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis