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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
TNFSF13B
💬
1. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Belimumab
Belimumab
💬
1. TNFSF13B
×
Name
Other Names
Belimumab
Belimumab (USAN)
Belimumab (genetical recombination) (JAN)
Benlysta (TN)
LymphoStat-B (TN)
ベリムマブ
ベンリスタ
Belimumab
13件:
11
11
,
13
,
43
,
44
,
46
,
49
,
51
,
53
,
63
,
66
,
222
,
296
,
300
💬
1. TNFSF13B
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
43
顕微鏡的多発血管炎
Microscopic polyangiitis
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
66
IgA腎症
IgA nephropathy
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
296
胆道閉鎖症
Biliary atresia
300
IgG4関連疾患
IgG4-related disease
2
TNFSF13B
💬
2. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Atacicept
Atacicept
💬
2. TNFSF13B
×
Name
Other Names
Atacicept
Atacicept (USAN/INN)
アタシセプト
Atacicept
4件:
13
13
,
46
,
49
,
66
💬
2. TNFSF13B
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
66
IgA腎症
IgA nephropathy
3
TNFSF13B
💬
3. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tabalumab
Tabalumab
💬
3. TNFSF13B
×
Name
Other Names
Tabalumab
Tabalumab (USAN)
Tabalumab (genetical recombination) (JAN)
タバルマブ
Tabalumab
2件:
46
46
,
49
💬
3. TNFSF13B
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
4
TNFSF13B
💬
4. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
4件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tibulizumab
Tibulizumab
💬
4. TNFSF13B
×
Name
Other Names
Tibulizumab
Tibulizumab (USAN/INN)
チブリズマブ
Tibulizumab
1件:
53
53
💬
4. TNFSF13B
×
告示番号
日本語名
英語名
53
シェーグレン症候群
Sjogren syndrome
5
TNFRSF13C
💬
5. TNFRSF13C
×
Name
Full Name
TNFRSF13C
TNF receptor superfamily member 13C
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Human T-cell leukemia virus 1 infection
,
Primary immunodeficiency
5件:
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Ianalumab
Ianalumab
💬
5. TNFRSF13C
×
Name
Other Names
Ianalumab
Ianalumab (USAN/INN)
アイアナルマブ
イアナルマブ
Ianalumab
7件:
35
35
,
46
,
49
,
53
,
61
,
63
,
95
💬
5. TNFRSF13C
×
告示番号
日本語名
英語名
35
天疱瘡
Pemphigus
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
53
シェーグレン症候群
Sjogren syndrome
61
自己免疫性溶血性貧血
Autoimmune hemolytic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
95
自己免疫性肝炎
Autoimmune hepatitis
6
IL4
💬
6. IL4
×
Name
Full Name
IL4
interleukin 4
16件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Leishmaniasis
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
16件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
Binetrakin
Binetrakin
💬
6. IL4
×
Name
Other Names
Binetrakin
Binetrakin (USAN/INN)
ビネトラキン
Binetrakin
1件:
46
46
💬
6. IL4
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
7
IL5
💬
7. IL5
×
Name
Full Name
IL5
interleukin 5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Mepolizumab
Mepolizumab
💬
7. IL5
×
Name
Other Names
Mepolizumab
Mepolizumab (USAN/INN)
Mepolizumab (genetical recombination) (JAN)
Nucala (TN)
メポリズマブ
ヌーカラ
Mepolizumab
4件:
44
44
,
45
,
98
,
162
💬
7. IL5
×
告示番号
日本語名
英語名
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
45
好酸球性多発血管炎性肉芽腫症;アレルギー性肉芽腫性血管炎;チャーグ・ストラウス症候群
Eosinophilic granulomatosis with Polyangiitis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
162
類天疱瘡(後天性表皮水疱症を含む。)
Pemphigoid
8
IL5
💬
8. IL5
×
Name
Full Name
IL5
interleukin 5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Reslizumab
Reslizumab
💬
8. IL5
×
Name
Other Names
Reslizumab
Reslizumab (USAN)
Cinqaero (TN)
Cinqair (TN)
レスリズマブ
Reslizumab
2件:
44
44
,
98
💬
8. IL5
×
告示番号
日本語名
英語名
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
9
IL6
💬
9. IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Pirfenidone
Pirfenidone
💬
9. IL6
×
Name
Other Names
Pirfenidone
Pirfenidone (JAN/USAN/INN)
Esbriet (TN)
ピルフェニドン
ピレスパ
Pirfenidone
11件:
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
💬
9. IL6
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
58
肥大型心筋症
Hypertrophic cardiomyopathy
84
サルコイドーシス
Sarcoidosis
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
164
眼皮膚白皮症
Oculocutaneous albinism
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
228
閉塞性細気管支炎
Bronchiolitis obliterans
10
IL6
💬
10. IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Pomalidomide
Pomalidomide
💬
10. IL6
×
Name
Other Names
Pomalidomide
Pomalidomide (JAN/USAN/INN)
Pomalyst (TN)
ポマリドミド
ポマリドマイド
ポマリスト
Pomalidomide
5件:
28
28
,
51
,
85
,
227
,
331
💬
10. IL6
×
告示番号
日本語名
英語名
28
全身性アミロイドーシス
Systemic amyloidosis
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
227
オスラー病;遺伝性出血性末梢血管拡張症
Osler disease
331
特発性多中心性キャッスルマン病
Idiopathic multicentric castleman disease