Target Gene/Pathway Pathway / Gene
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Showing 1 to 6 of 6 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
TPH2
💬1. TPH2
| [4] Tryptophan metabolism Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse | Telotristat
Telotristat
💬1. TPH2
| Telotristat | [1] 97 97 💬1. TPH2
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| 2 |
DHFR
💬2. DHFR
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬2. DHFR
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 2. DHFR
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| 3 |
DHFR2
💬3. DHFR2
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬3. DHFR2
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 3. DHFR2
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| 4 |
ALPL
💬4. ALPL
| [4] Thiamine metabolism Thiamine metabolism, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors | Asfotase alfa
Asfotase alfa
💬4. ALPL
| Asfotase alfa | [1] 172 172 💬4. ALPL
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| 5 |
PAH
💬5. PAH
| [5] Phenylalanine metabolism Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthesis, Metabolic pathways, Biosynthesis of amino acids [5] Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthes ... | Pegvaliase
Pegvaliase
💬5. PAH
| Pegvaliase | [1] 240 240 💬5. PAH
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| 6 |
TPH1
💬6. TPH1
| [4] Tryptophan metabolism Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse | Telotristat
Telotristat
💬6. TPH1
| Telotristat | [1] 97 97 💬6. TPH1
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