Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 NQO1 💬 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin 💬 Warfarin [11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
2 NCSTN 💬 [2] Notch signaling pathway, Alzheimer disease Tarenflurbil 💬 Tarenflurbil [1] 13 💬
3 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone [10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
4 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone acetate 💬 Hydrocortisone acetate [1] 97 💬
5 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone [8] 2, 28, 46, 65, 83, 90, 96, 235 💬
6 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Budesonide 💬 Budesonide [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
7 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone [22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
8 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
9 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone [46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
10 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone [42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
11 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone [45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
12 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Mifepristone 💬 Mifepristone [1] 75 💬
13 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Beclomethasone dipropionate 💬 Beclomethasone dipropionate [3] 85, 97, 98 💬
14 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Mometasone furoate 💬 Mometasone furoate [2] 98, 162 💬
15 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Cortisone acetate 💬 Cortisone acetate [1] 81 💬
16 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone cypionate 💬 Hydrocortisone cypionate [3] 6, 81, 83 💬
17 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisolone acetate 💬 Prednisolone acetate [1] 222 💬
18 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Clobetasol propionate 💬 Clobetasol propionate [2] 46, 162 💬
19 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone succinate 💬 Hydrocortisone succinate [3] 6, 81, 83 💬
20 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Ciclesonide 💬 Ciclesonide [1] 84 💬
21 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Fluticasone propionate 💬 Fluticasone propionate [2] 98, 228 💬
22 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Fluocinolone acetonide 💬 Fluocinolone acetonide [1] 90 💬
23 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Deflazacort 💬 Deflazacort [2] 30, 113 💬
24 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone hemisuccinate 💬 Methylprednisolone hemisuccinate [7] 13, 49, 50, 51, 53, 97, 211 💬
25 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Halometasone 💬 Halometasone [1] 162 💬
26 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Clobetasol 💬 Clobetasol [4] 39, 46, 51, 162 💬
27 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Cortisone 💬 Cortisone [1] 81 💬
28 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Fluticasone 💬 Fluticasone [3] 98, 228, 299 💬
29 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Mometasone 💬 Mometasone [2] 98, 162 💬
30 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone acetate 💬 Prednisone acetate [6] 35, 41, 46, 49, 162, 224 💬
31 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Vamorolone 💬 Vamorolone [2] 97, 113 💬
32 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Relacorilant 💬 Relacorilant [1] 75 💬
33 NPC1L1 💬 [1] Fat digestion and absorption Ezetimibe 💬 Ezetimibe [4] 49, 79, 93, 260 💬
34 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Spironolactone 💬 Spironolactone [8] 46, 58, 67, 86, 113, 210, 218, 225 💬
35 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Eplerenone 💬 Eplerenone [4] 75, 113, 210, 215 💬
36 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Fludrocortisone 💬 Fludrocortisone [3] 6, 17, 81 💬
37 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Aldosterone 💬 Aldosterone [1] 222 💬
38 NFE2L2 💬 [7] Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone [1] 18 💬
39 NFKB1 💬 [76] Antifolate resistance, MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Cellular senescence, Osteoclast differentiation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Relaxin signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Pancreatic cancer, Prostate cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
40 NGF 💬 [9] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels Tanezumab 💬 Tanezumab [2] 226, 298 💬
41 NGFR 💬 [9] Virion - Lyssavirus, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer Cenegermin 💬 Cenegermin [2] 53, 90 💬
42 NPR1 💬 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬
43 NPR1 💬 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Nesiritide 💬 Nesiritide [2] 46, 58 💬
44 NPR2 💬 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬
45 NPR2 💬 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway Vosoritide 💬 Vosoritide [1] 276 💬
46 NR1H4 💬 [1] Bile secretion Chenodiol 💬 Chenodeoxycholic acid [4] 20, 96, 234, 263 💬
47 NR1H4 💬 [1] Bile secretion Ursodiol 💬 Ursodeoxycholic acid [14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
48 NR1H4 💬 [1] Bile secretion Obeticholic acid 💬 Obeticholic acid [3] 93, 265, 296 💬
49 NR1H4 💬 [1] Bile secretion Cholic acid 💬 Cholic Acid [4] 20, 234, 265, 310 💬
50 NR1H4 💬 [1] Bile secretion Tropifexor 💬 Tropifexor [1] 93 💬