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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
RGMA
💬
1. RGMA
×
Name
Full Name
RGMA
repulsive guidance molecule BMP co-receptor a
[2]
TGF-beta signaling pathway
TGF-beta signaling pathway
,
Axon guidance
Elezanumab
Elezanumab
💬
1. RGMA
×
Name
Other Names
Elezanumab
Elezanumab (USAN/INN)
Elezanumab
[1]
13
13
💬
1. RGMA
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
2
RTN4
💬
2. RTN4
×
Name
Full Name
RTN4
reticulon 4
[1]
Alzheimer disease
Alzheimer disease
Ozanezumab
Ozanezumab
💬
2. RTN4
×
Name
Other Names
Ozanezumab
Ozanezumab (USAN)
Ozanezumab
[1]
2
2
💬
2. RTN4
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
3
RAF1
💬
3. RAF1
×
Name
Full Name
RAF1
Raf-1 proto-oncogene, serine/threonine kinase
[83]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Chemokine signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Autophagy - animal
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
Apoptosis
,
Cellular senescence
,
Vascular smooth muscle contraction
,
Axon guidance
,
VEGF signaling pathway
,
Apelin signaling pathway
,
Focal adhesion
,
Gap junction
,
Signaling pathways regulating pluripotency of stem cells
,
Neutrophil extracellular trap formation
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
T cell receptor signaling pathway
,
B cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Fc gamma R-mediated phagocytosis
,
Long-term potentiation
,
Neurotrophin signaling pathway
,
Serotonergic synapse
,
Long-term depression
,
Regulation of actin cytoskeleton
,
Insulin signaling pathway
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Estrogen signaling pathway
,
Melanogenesis
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
GnRH secretion
,
Growth hormone synthesis, secretion and action
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Alcoholism
,
Salmonella infection
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Renal cell carcinoma
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Acute myeloid leukemia
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
[83]
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Sorafenib
Sorafenib
💬
3. RAF1
×
Name
Other Names
Sorafenib
Sorafenib (USAN/INN)
Sorafenib
[2]
34
34
,
86
💬
3. RAF1
×
Disease ID
Name
34
Neurofibromatosis
86
Pulmonary arterial hypertension
4
RARA
💬
4. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Tretinoin
Tretinoin
💬
4. RARA
×
Name
Other Names
Tretinoin
Tretinoin (JAN/USP/INN)
Avita (TN)
Renova (TN)
Retin A (TN)
Tretinoin (TN)
ALTRENO
ATRALIN
RETIN-A
RETIN-A MICRO
TRETINOIN CREAM
Tretinoin
[6]
2
2
,
62
,
63
,
75
,
94
,
231
💬
4. RARA
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
62
Paroxysmal nocturnal hemoglobinuria
63
Idiopathic thrombocytopenic purpura
75
Cushing disease
94
Primary sclerosing cholangitis
231
Alpha-1-antitrypsin deficiency
5
RARA
💬
5. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Isotretinoin
Isotretinoin
💬
5. RARA
×
Name
Other Names
Isotretinoin
Isotretinoin (JAN/USP)
Absorica (TN)
Accutane (TN)
Sotret (TN)
AMNESTEEM
CLARAVIS
MYORISAN
ZENATANE
Isotretinoin
[4]
36
36
,
39
,
159
,
160
💬
5. RARA
×
Disease ID
Name
36
Epidermolysis bullosa
39
Toxic epidermal necrolysis
159
Xeroderma pigmentosum
160
Congenital ichthyosis
6
RARA
💬
6. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Tamibarotene
Tamibarotene
💬
6. RARA
×
Name
Other Names
Tamibarotene
Tamibarotene (JAN/USAN/INN)
Am 80
Amnoid (TN)
Tamibarotene
[2]
26
26
,
96
💬
6. RARA
×
Disease ID
Name
26
HTLV-1-associated myelopathy
96
Crohn disease
7
RARA
💬
7. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Acitretin
Acitretin
💬
7. RARA
×
Name
Other Names
Acitretin
Acitretin (USP/INN)
Soriatane (TN)
Acitretin
[1]
37
37
💬
7. RARA
×
Disease ID
Name
37
Generalised pustular psoriasis
8
RARA
💬
8. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Alitretinoin
Alitretinoin
💬
8. RARA
×
Name
Other Names
Alitretinoin
Alitretinoin (USAN)
Panretin (TN)
Alitretinoin
[1]
49
49
💬
8. RARA
×
Disease ID
Name
49
Systemic lupus erythematosus
9
RARA
💬
9. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Fenretinide
Fenretinide
💬
9. RARA
×
Name
Other Names
Fenretinide
Fenretinide (USAN/INN)
Fenretinide
[1]
299
299
💬
9. RARA
×
Disease ID
Name
299
Cystic fibrosis
10
RARA
💬
10. RARA
×
Name
Full Name
RARA
retinoic acid receptor alpha
[5]
Th17 cell differentiation
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[5]
Th17 cell differentiation
,
Estrogen signaling pathway
,
Pathways in cancer
,
Transcriptional misre
...
Vitamin A
Vitamin A
💬
10. RARA
×
Name
Other Names
Vitamin A
Vitamin A (USP)
Retinol
Vitamin A1
Aquasol A (TN)
Vitamin A
[3]
13
13
,
53
,
90
💬
10. RARA
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
53
Sjogren syndrome
90
Retinitis pigmentosa