Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases

Dextromethorphan 💬

Dextromethorphan

[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
78	Hypopituitarism
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome

2

[2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases

Fenfluramine 💬

[4] 140, 144, 145, 149 💬

3

[2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases

Blarcamesine 💬

[1] 156 💬

4

-

Benzbromarone 💬

[1] 86 💬

5

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

Fingolimod 💬

[3] 13, 14, 156 💬

6

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

Amiselimod 💬

[1] 97 💬

7

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

[3] 96, 97, 98 💬

8

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

[3] 13, 96, 97 💬

9

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

[1] 13 💬

10

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

[1] 49 💬

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