Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...

Thrombomodulin alfa 💬

Thrombomodulin Alfa

[1] 85 💬

2

[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...

Dabigatran etexilate 💬

Dabigatran etexilate

[2] 51, 75 💬

3

[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...

Dabigatran 💬

[5] 51, 75, 85, 91, 124 💬

4

[1] Complement and coagulation cascades

Desmopressin 💬

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

5

[1] Complement and coagulation cascades

Emicizumab 💬

[1] 288 💬

6

[1] Complement and coagulation cascades

[1] 222 💬

7

[1] Complement and coagulation cascades

Rivaroxaban 💬

[4] 46, 49, 91, 210 💬

8

[1] Complement and coagulation cascades

[2] 46, 88 💬

9

[1] Complement and coagulation cascades

Emicizumab 💬

[1] 288 💬

10

[4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...

Omalizumab 💬

[7] 46, 53, 65, 98, 162, 226, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
53	Sjogren syndrome
65	Primary immunodeficiency
98	Eosinophilic gastrointestinal disease
162	Pemphigoid
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

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