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Drug
Target Gene/Pathway
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Drug
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drugs per page:
Showing 1 to 10 of 38 drugs
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No.
KEGG DRUG
DrugBank
薬物名(臨床試験情報から抽出)
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Tacrolimus
1件:
Tacrolimus
Tacrolimus
2件:
Prograf
Prograf
;
Tacrolimus
;
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
34件:
2
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
164
,
222
,
224
,
226
,
227
,
228
,
283
,
284
,
285
,
286
,
299
34件:
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
16
...
2
Trimethoprim
1件:
Trimethoprim
Trimethoprim
2件:
Bactrim
Bactrim
;
Trimethoprim
;
-
-
8件:
36
36
,
44
,
49
,
60
,
61
,
85
,
298
,
299
3
Cyclosporine
1件:
Cyclosporine
Cyclosporine
10件:
CICLOSPORIN
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine A
;
Ikervis
;
Neoral
;
RESTASIS
;
10件:
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine
...
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
44件:
11
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
,
65
,
90
,
93
,
95
,
97
,
107
,
113
,
162
,
164
,
222
,
226
,
228
,
234
,
269
,
274
,
283
,
284
,
285
,
302
,
326
44件:
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
, ...
4
Atovaquone
1件:
Atovaquone
Atovaquone
1件:
ATOVAQUONE
ATOVAQUONE
;
-
-
1件:
61
61
5
Famotidine
1件:
Famotidine
Famotidine
2件:
FAMOTIDINA
FAMOTIDINA
;
Famotidine
;
1件:
HRH2
HRH2
💬
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Gastric acid secretion
,
Neuroactive ligand-receptor interaction
💬
6件:
6
6
,
46
,
61
,
86
,
98
,
107
6
Sulfamethoxazole
1件:
Sulfamethoxazole
Sulfamethoxazole
3件:
Bactrim
Bactrim
;
SULFAMETHOXAZOLE
;
Sulphamethoxazole
;
-
-
5件:
44
44
,
49
,
61
,
85
,
299
7
Prednisolone
1件:
Prednisolone
Prednisolone
3件:
Prednisolona
Prednisolona
;
Prednisolone
;
Prednisolonum
;
1件:
NR3C1
NR3C1
💬
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
💬
42件:
3
3
,
11
,
13
,
14
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
,
66
,
75
,
81
,
84
,
85
,
95
,
96
,
97
,
107
,
113
,
145
,
162
,
222
,
269
,
271
,
296
,
299
,
300
42件:
3
,
11
,
13
,
14
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
, ...
8
Prednisone
1件:
Prednisone
Prednisone
3件:
Prednisona
Prednisona
;
Prednisone
;
RAYOS
;
1件:
NR3C1
NR3C1
💬
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
💬
45件:
2
2
,
11
,
13
,
14
,
19
,
26
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
,
81
,
84
,
85
,
86
,
95
,
96
,
97
,
113
,
162
,
164
,
205
,
222
,
224
,
228
,
283
,
284
,
288
,
299
,
300
,
307
,
331
45件:
2
,
11
,
13
,
14
,
19
,
26
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
, ...
9
Mycophenolate mofetil
1件:
Mycophenolate mofetil
Mycophenolate mofetil
3件:
CELLCEPT
CELLCEPT
;
MYCOPHENOLATE MOFETIL
;
Mycophenolate mofetil TEVA
;
2件:
IMPDH1
IMPDH1
,
IMPDH2
💬
4件:
Drug metabolism - other enzymes
Drug metabolism - other enzymes
,
Metabolic pathways
,
Nucleotide metabolism
,
Purine metabolism
💬
4件:
Drug metabolism - other enzymes
,
Metabolic pathways
,
Nucleotide metabolism
,
Purine metabolism
💬
...
34件:
2
2
,
11
,
13
,
19
,
20
,
28
,
35
,
36
,
42
,
43
,
44
,
45
,
49
,
51
,
53
,
60
,
61
,
62
,
65
,
66
,
85
,
93
,
95
,
96
,
162
,
164
,
222
,
224
,
226
,
234
,
283
,
284
,
285
,
300
34件:
2
,
11
,
13
,
19
,
20
,
28
,
35
,
36
,
42
,
43
,
44
,
45
,
49
,
51
,
53
,
60
,
61
,
62
,
65
,
66
,
85
,
93
,
95
,
96
, ...
10
Sirolimus
1件:
Sirolimus
Sirolimus
3件:
Rapamune
Rapamune
;
Rapamycin
;
SIROLIMUS
;
1件:
MTOR
MTOR
💬
51件:
AMPK signaling pathway
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Apelin signaling pathway
,
Autophagy - animal
,
Autophagy - other
,
Breast cancer
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chemical carcinogenesis - receptor activation
,
Choline metabolism in cancer
,
Colorectal cancer
,
Diabetic cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Gastric cancer
,
Glioma
,
Growth hormone synthesis, secretion and action
,
HIF-1 signaling pathway
,
Hepatocellular carcinoma
,
Herpes simplex virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Huntington disease
,
Insulin resistance
,
Insulin signaling pathway
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
MicroRNAs in cancer
,
Neutrophil extracellular trap formation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Shigellosis
,
Spinocerebellar ataxia
,
Th17 cell differentiation
,
Thermogenesis
,
Thyroid hormone signaling pathway
,
Type II diabetes mellitus
,
mTOR signaling pathway
💬
51件:
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer dise
...
40件:
2
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
,
98
,
137
,
157
,
158
,
192
,
193
,
222
,
256
,
277
,
278
,
279
,
280
,
281
,
283
,
300
,
331
40件:
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
, ...