Disease The intractable diseases designated by MHLW, Japan
Diseases : 338 - Clinical trials : 34,520 / Drugs : 19,957 - ( DrugBank : 2,195 ) / Drug target genes : 613 - Drug target pathways : 297
Disease group: Cardiovascular diseasesShowing 1 to 10 of 21 diseases
ID | Disease name [Group] | Clinical trial Phase 1 / 2 / 3 / 4 | Drug [ DrugBank ] | Target gene Target pathway | Domestic patients (1) MHLW, (2) Med expenses recipients (FY2021) |
---|---|---|---|---|---|
57 | Idiopathic dilated cardiomyopathy [Card] 💬 | 11 11 trials 3 / 6 / 1 / 3 💬 | 23 23 drugs [ 12 12 drugs ] | 9 9 genes 35 pathways | 18724 (1) 27,968 patients (2) 18,724 patients Age distribution ![]() |
58 | Hypertrophic cardiomyopathy [Card] 💬 "HCM", "Nonobstructive hypertrophic cardiomyopathy", "Nonobstructive HCM", "Obstructive hypertrophic cardiomyopathy", "Obstructive HCM", "OHCM", "Hypertrophic obstructive cardiomyopathy", "HOCM", "Mid-ventricular obstructive hypertrophic cardiomyopathy", "MVOHCM", "Mid-ventricular hypertrophic obstructive cardiomyopathy", "MVHOCM", "Apical hypertrophic cardiomyopathy", "APH", "Expansion phase hypertrophic cardiomyopathy" "HCM", "Nonobstructive hypertrophic cardiomyopathy", "Nonobstructive HCM", "Obstructive hypertrophic ... | 126 126 trials 21 / 55 / 43 / 14 💬 | 135 135 drugs [ 42 42 drugs ] | 46 46 genes 162 pathways | 4201 (1) 4,667 patients (2) 4,201 patients Age distribution ![]() |
59 | Restricted cardiomyopathy [Card] 💬 "Restrictive cardiomyopathy", "Constrictive cardiomyopathy" | 0 - | 0 - | 0 - | 60 (1) 50 patients (2) 60 patients Age distribution ![]() |
207 | Persistent truncus arteriosus [Card] 💬 "Persistent truncus arteriosus type I", "Persistent truncus arteriosus type II", "Persistent truncus arteriosus type III", "Persistent truncus arteriosus type IV" "Persistent truncus arteriosus type I", "Persistent truncus arteriosus type II", "Persistent truncus ... | 0 - | 0 - | 0 - | 32 (1) About 500 patients (2) 32 patients Age distribution ![]() |
208 | Corrected transposition of great arteries [Card] 💬 | 0 - | 0 - | 0 - | 186 (1) [Disease ID 208-209 total] About 900 patients (2) 186 patients Age distribution ![]() |
209 | Complete transposition of great vessel [Card] 💬 "Complete transposition of great arteries", "Complete TGA", "Complete transposition of great vessel type I", "Complete transposition of great arteries type I", "Complete TGA type I", "Complete transposition of great vessel type II", "Complete transposition of great arteries type II", "Complete TGA type II", "Complete transposition of great vessel type III", "Complete transposition of great arteries type III", "Complete TGA type III", "Complete transposition of great vessel type IV", "Complete transposition of great arteries type IV", "Complete TGA type IV" "Complete transposition of great arteries", "Complete TGA", "Complete transposition of great vessel ... | 0 - | 0 - | 0 - | 244 (1) [Disease ID 208-209 total] About 900 patients (2) 244 patients Age distribution ![]() |
210 | Single Ventricle [Card] 💬 "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulation syndrome" "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulatio ... | 51 51 trials 23 / 15 / 24 / 6 💬 | 53 53 drugs [ 22 22 drugs ] | 32 32 genes 67 pathways | 425 (1) [Disease ID 210-213 total] About 3,500 patients (Patients of single ventricle heart defects) (2) 425 patients Age distribution ![]() |
211 | Hypoplastic left heart syndrome [Card] 💬 "HLHS" | 22 22 trials 10 / 11 / 1 / 0 💬 | 29 29 drugs [ 9 9 drugs ] | 5 5 genes 14 pathways | 54 (1) [Disease ID 210-213 total] About 3,500 patients (Patients of single ventricle heart defects) (2) 54 patients Age distribution ![]() |
212 | Tricuspid atresia [Card] 💬 "TA" | 5 5 trials 2 / 2 / 0 / 0 💬 | 6 6 drugs [ 6 6 drugs ] | 8 8 genes 12 pathways | 183 (1) [Disease ID 210-213 total] About 3,500 patients (Patients of single ventricle heart defects) (2) 183 patients Age distribution ![]() |
213 | Pulmonary atresia without ventricular septum defect [Card] 💬 "Pulmonary atresia with intact ventricular septum", "Pulmonary atresia" | 0 - | 0 - | 0 - | 140 (1) [Disease ID 210-213 total] About 3,500 patients (Patients of single ventricle heart defects) (2) 140 patients Age distribution ![]() |