Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MASP2 [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11531 Narsoplimab [4] 64, 66, 109, 222
2 CFD [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11641 Danicopan [1] 62
3 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D06410 Thrombomodulin Alfa [1] 85
4 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D07144 Dabigatran etexilate [2] 51, 75
5 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D09707 Dabigatran [5] 51, 75, 85, 91, 124
6 F8 [1] Complement and coagulation cascades D00291 Desmopressin [6] 6, 64, 72, 75, 225, 288
7 F9 [1] Complement and coagulation cascades D10821 Emicizumab [1] 288
8 F10 [1] Complement and coagulation cascades D03213 Apixaban [1] 222
9 F10 [1] Complement and coagulation cascades D07086 Rivaroxaban [4] 46, 49, 91, 210
10 F10 [1] Complement and coagulation cascades D09710 Edoxaban [2] 46, 88
11 F10 [1] Complement and coagulation cascades D10821 Emicizumab [1] 288
12 SERPIND1 [1] Complement and coagulation cascades D08547 Sulodexide [2] 51, 271
13 KLKB1 [1] Complement and coagulation cascades D10845 Conestat alfa [1] 61
14 SERPINC1 [1] Complement and coagulation cascades D07510 Heparin [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317
15 SERPINC1 [1] Complement and coagulation cascades D07510 Enoxaparin [1] 46
16 SERPINC1 [1] Complement and coagulation cascades D07510 Parnaparin [1] 97
17 SERPINC1 [1] Complement and coagulation cascades D08547 Sulodexide [2] 51, 271
18 PLG [4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D00160 Aminocaproic acid [1] 70
19 PLG [4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D01136 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299
20 CFB [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D12251 Iptacopan [5] 61, 62, 66, 109, 222
21 C1R [6] Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa [1] 61
22 C1S [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa [1] 61
23 C1S [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11530 Sutimlimab [1] 61
24 C3 [15] Neuroactive ligand-receptor interaction, Phagosome, Complement and coagulation cascades, Neutrophil extracellular trap formation, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan [4] 2, 61, 62, 222
25 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222
26 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11054 Ravulizumab [7] 2, 11, 13, 50, 62, 66, 109
27 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11473 Nomacopan [3] 62, 109, 162
28 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11477 Pozelimab [2] 11, 62
29 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11696 Crovalimab [2] 62, 109
30 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11838 Vilobelimab [3] 43, 44, 269
31 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D12357 Zilucoplan [3] 2, 11, 62
32 C5AR1 [5] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11093 Avacopan [3] 43, 44, 222
33 VWF [8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Complement and coagulation cascades, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection, Coronavirus disease - COVID-19 D11160 Caplacizumab [1] 64