Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CCN2	[1] Hippo signaling pathway	D10969	Pamrevlumab	[2] 85, 113
2	SMAD7	[2] TGF-beta signaling pathway, Hippo signaling pathway	D10956	Mongersen	[2] 96, 97
3	TGFB1	[20] MAPK signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling ...	D09620	Fresolimumab	[3] 51, 85, 222
4	TGFB2	[17] MAPK signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling ...	D09620	Fresolimumab	[3] 51, 85, 222
5	TGFB3	[14] MAPK signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, Leishmaniasis, Mal ...	D09620	Fresolimumab	[3] 51, 85, 222

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