Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
2	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
3	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00522 💬	Candesartan	[2] 58, 67 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00626 💬	Candesartan cilexetil	[1] 67 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00523 💬	Irbesartan	[4] 66, 167, 168, 222 💬
6	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D08146 💬	Losartan	[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
7	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00627 💬	Telmisartan	[2] 66, 67 💬
9	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬

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