Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
2 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
3 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
4 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
5 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
6 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
7 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
8 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
9 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
10 GABAergic synapse 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
11 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
12 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
13 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
14 Morphine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
15 Neuroactive ligand-receptor interaction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
16 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
17 Neuroactive ligand-receptor interaction 💬
[1] NR3C1 💬 D00473 💬 Prednisone [45]  2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
18 Nicotine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
19 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
20 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
21 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
22 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
23 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
24 Retrograde endocannabinoid signaling 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
25 Serotonergic synapse 💬
[3] GABRB1, GABRB2, GABRB3 💬 D11149 💬 Brexanolone [1] 205 💬
26 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
27 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
28 Taste transduction 💬
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D11149 💬 Brexanolone [1] 205 💬