Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] BRAF 💬	D10064 💬	Dabrafenib	[1] 34 💬
2	Acute myeloid leukemia 💬	[4] BRAF, FLT3, KIT, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
3	Acute myeloid leukemia 💬	[3] CSF1R, FLT3, KIT 💬	D11270 💬	Pexidartinib	[1] 34 💬
4	Acute myeloid leukemia 💬	[3] CSF1R, FLT3, KIT 💬	D08552 💬	Sunitinib	[2] 28, 34 💬
5	Acute myeloid leukemia 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6	Acute myeloid leukemia 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
7	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
8	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
9	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
10	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬

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