Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
2	AGE-RAGE signaling pathway in diabetic complications 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
3	Alcoholic liver disease 💬	[1] C5 💬	D11838 💬	Vilobelimab	[3] 43, 44, 269 💬
4	Alcoholic liver disease 💬	[1] C5AR1 💬	D11093 💬	Avacopan	[3] 43, 44, 222 💬
5	Allograft rejection 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271 ...
6	Allograft rejection 💬	[1] IL5 💬	D04923 💬	Mepolizumab	[4] 44, 45, 98, 162 💬
7	Allograft rejection 💬	[1] IL5 💬	D08985 💬	Reslizumab	[2] 44, 98 💬
8	Antifolate resistance 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
9	Asthma 💬	[1] IL5 💬	D04923 💬	Mepolizumab	[4] 44, 45, 98, 162 💬
10	Asthma 💬	[1] IL5 💬	D08985 💬	Reslizumab	[2] 44, 98 💬

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