Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 C-type lectin receptor signaling pathway 💬
 [4] IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 C-type lectin receptor signaling pathway 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
3 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
4 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
5 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
6 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 D10912 💬 Brazikumab [2] 96, 97 💬
7 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 D10438 💬 Guselkumab [5] 37, 41, 51, 96, 97 💬
8 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 D11123 💬 Mirikizumab [3] 37, 96, 97 💬
9 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 D11052 💬 Risankizumab [4] 37, 96, 97, 271 💬
10 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 D10400 💬 Tildrakizumab [2] 162, 271 💬
11 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
12 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
13 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
14 C-type lectin receptor signaling pathway 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
15 C-type lectin receptor signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
16 C-type lectin receptor signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
17 C-type lectin receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
18 C-type lectin receptor signaling pathway 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
19 C-type lectin receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
20 C-type lectin receptor signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
21 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
22 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
23 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
24 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
25 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
26 C-type lectin receptor signaling pathway 💬
 [1] PRKCD 💬 D09671 💬 Sotrastaurin [1] 97 💬
27 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
28 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
29 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
30 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
31 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
32 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
33 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
34 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
35 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
36 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
37 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
38 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
39 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
40 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
41 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
42 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
43 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
44 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
45 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
46 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
47 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
48 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
49 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
50 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
51 C-type lectin receptor signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
52 C-type lectin receptor signaling pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
53 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
54 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
55 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
56 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
57 C-type lectin receptor signaling pathway 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
58 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
59 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
60 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
61 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
62 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
63 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
64 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
65 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
66 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬