Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CCR4 1件: Viral protein interaction with cytokine and cytokine receptor D09761 Mogamulizumab 1件: 26
2 CCR5 1件: Viral protein interaction with cytokine and cytokine receptor D06670 Maraviroc 2件: 46, 84
3 CCR5 1件: Viral protein interaction with cytokine and cytokine receptor D09878 Cenicriviroc 1件: 94
4 CSF1 1件: Viral protein interaction with cytokine and cytokine receptor D06402 Sunitinib 2件: 28, 34
5 CSF1 1件: Viral protein interaction with cytokine and cytokine receptor D08552 Sunitinib 2件: 28, 34
6 CSF1R 1件: Viral protein interaction with cytokine and cytokine receptor D11270 Pexidartinib 1件: 34
7 IL2RA 1件: Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
8 IL2RA 1件: Viral protein interaction with cytokine and cytokine receptor D03058 Basiliximab 6件: 2, 50, 66, 97, 222, 228
9 IL2RA 1件: Viral protein interaction with cytokine and cytokine receptor D03639 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284
10 IL2RB 1件: Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
11 IL2RG 1件: Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
12 IL6 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
13 IL6 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
14 IL6 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D09669 Siltuximab 2件: 28, 331
15 IL6 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D10080 Sirukumab 2件: 41, 46
16 IL6R 1件: Viral protein interaction with cytokine and cytokine receptor D02596 Tocilizumab 21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
17 IL6R 1件: Viral protein interaction with cytokine and cytokine receptor D10161 Sarilumab 5件: 41, 46, 84, 107, 271
18 IL6R 1件: Viral protein interaction with cytokine and cytokine receptor D11079 Satralizumab 2件: 11, 13
19 CXCR1 1件: Viral protein interaction with cytokine and cytokine receptor D08984 Reparixin 2件: 298, 299
20 CXCR2 1件: Viral protein interaction with cytokine and cytokine receptor D08984 Reparixin 2件: 298, 299
21 IL10 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
22 LTA 1件: Viral protein interaction with cytokine and cytokine receptor D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
23 LTA 1件: Viral protein interaction with cytokine and cytokine receptor D10187 Pateclizumab 1件: 46
24 IL20 1件: Viral protein interaction with cytokine and cytokine receptor D11756 Fletikumab 1件: 46
25 CCL2 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
26 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
27 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
28 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
29 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D02597 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
30 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
31 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
32 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
33 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
34 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D05393 Pegsunercept 1件: 46
35 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
36 TNF 2件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D09944 Ozoralizumab 1件: 46
37 CCR2 1件: Viral protein interaction with cytokine and cytokine receptor D09878 Cenicriviroc 1件: 94
38 CXCR4 1件: Viral protein interaction with cytokine and cytokine receptor D08971 Plerixafor 6件: 19, 20, 51, 65, 285, 299