Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00045 Adenosine [3] 13, 58, 65
2 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00227 Aminophylline [1] 63
3 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00371 Theophylline [2] 236, 299
4 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
5 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
6 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D01712 Theophylline [2] 236, 299
7 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D02017 Theophylline [2] 236, 299
8 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D02769 Adenosine phosphate [1] 46
9 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D05429 Aminophylline [1] 63
10 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D06103 Theophylline [2] 236, 299
11 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D06104 Theophylline [2] 236, 299
12 ADRB1 [2] Renin secretion, Salivary secretion D00076 Norepinephrine [1] 22
13 ADRB1 [2] Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
14 ADRB1 [2] Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
15 ADRB1 [2] Renin secretion, Salivary secretion D00235 Atenolol [1] 167
16 ADRB1 [2] Renin secretion, Salivary secretion D00255 Carvedilol [5] 6, 57, 86, 113, 210
17 ADRB1 [2] Renin secretion, Salivary secretion D00378 Timolol [2] 157, 227
18 ADRB1 [2] Renin secretion, Salivary secretion D00432 Nadolol [1] 6
19 ADRB1 [2] Renin secretion, Salivary secretion D00483 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
20 ADRB1 [2] Renin secretion, Salivary secretion D00485 Pseudoephedrine [1] 17
21 ADRB1 [2] Renin secretion, Salivary secretion D00601 Metoprolol [6] 17, 57, 58, 113, 193, 226
22 ADRB1 [2] Renin secretion, Salivary secretion D00603 Timolol [2] 157, 227
23 ADRB1 [2] Renin secretion, Salivary secretion D00632 Dobutamine [3] 57, 58, 215
24 ADRB1 [2] Renin secretion, Salivary secretion D00634 Bisoprolol [3] 67, 86, 113
25 ADRB1 [2] Renin secretion, Salivary secretion D00636 Amiodarone [2] 28, 127
26 ADRB1 [2] Renin secretion, Salivary secretion D00644 Esmolol [1] 58
27 ADRB1 [2] Renin secretion, Salivary secretion D00996 Epinephrine [3] 46, 70, 96
28 ADRB1 [2] Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
29 ADRB1 [2] Renin secretion, Salivary secretion D02149 Epinephrine [3] 46, 70, 96
30 ADRB1 [2] Renin secretion, Salivary secretion D02342 Bisoprolol [3] 67, 86, 113
31 ADRB1 [2] Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
32 ADRB1 [2] Renin secretion, Salivary secretion D02358 Metoprolol [6] 17, 57, 58, 113, 193, 226
33 ADRB1 [2] Renin secretion, Salivary secretion D02910 Amiodarone [2] 28, 127
34 ADRB1 [2] Renin secretion, Salivary secretion D03415 Carvedilol [5] 6, 57, 86, 113, 210
35 ADRB1 [2] Renin secretion, Salivary secretion D03879 Dobutamine [3] 57, 58, 215
36 ADRB1 [2] Renin secretion, Salivary secretion D03880 Dobutamine [3] 57, 58, 215
37 ADRB1 [2] Renin secretion, Salivary secretion D03881 Dobutamine [3] 57, 58, 215
38 ADRB1 [2] Renin secretion, Salivary secretion D05011 Metoprolol [6] 17, 57, 58, 113, 193, 226
39 ADRB1 [2] Renin secretion, Salivary secretion D05127 Nebivolol [4] 17, 85, 113, 167
40 ADRB1 [2] Renin secretion, Salivary secretion D05206 Norepinephrine [1] 22
41 ADRB1 [2] Renin secretion, Salivary secretion D05648 Pseudoephedrine [1] 17
42 ADRB1 [2] Renin secretion, Salivary secretion D05649 Pseudoephedrine [1] 17
43 ADRB1 [2] Renin secretion, Salivary secretion D07660 Celiprolol [1] 168
44 ADRB1 [2] Renin secretion, Salivary secretion D07916 Esmolol [1] 58
45 ADRB1 [2] Renin secretion, Salivary secretion D08443 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
46 ADRB1 [2] Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
47 ADRB1 [2] Renin secretion, Salivary secretion D08600 Timolol [2] 157, 227
48 ADRB2 [2] Renin secretion, Salivary secretion D00076 Norepinephrine [1] 22
49 ADRB2 [2] Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
50 ADRB2 [2] Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
51 ADRB2 [2] Renin secretion, Salivary secretion D00255 Carvedilol [5] 6, 57, 86, 113, 210
52 ADRB2 [2] Renin secretion, Salivary secretion D00378 Timolol [2] 157, 227
53 ADRB2 [2] Renin secretion, Salivary secretion D00432 Nadolol [1] 6
54 ADRB2 [2] Renin secretion, Salivary secretion D00483 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
55 ADRB2 [2] Renin secretion, Salivary secretion D00485 Pseudoephedrine [1] 17
56 ADRB2 [2] Renin secretion, Salivary secretion D00603 Timolol [2] 157, 227
57 ADRB2 [2] Renin secretion, Salivary secretion D00687 Salmeterol [1] 299
58 ADRB2 [2] Renin secretion, Salivary secretion D00688 Terbutaline [1] 118
59 ADRB2 [2] Renin secretion, Salivary secretion D00996 Epinephrine [3] 46, 70, 96
60 ADRB2 [2] Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
61 ADRB2 [2] Renin secretion, Salivary secretion D01373 Formoterol [3] 85, 228, 299
62 ADRB2 [2] Renin secretion, Salivary secretion D02147 Salbutamol [14] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
63 ADRB2 [2] Renin secretion, Salivary secretion D02149 Epinephrine [3] 46, 70, 96
64 ADRB2 [2] Renin secretion, Salivary secretion D02151 Tulobuterol [1] 6
65 ADRB2 [2] Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
66 ADRB2 [2] Renin secretion, Salivary secretion D03415 Carvedilol [5] 6, 57, 86, 113, 210
67 ADRB2 [2] Renin secretion, Salivary secretion D05206 Norepinephrine [1] 22
68 ADRB2 [2] Renin secretion, Salivary secretion D05277 Formoterol [3] 85, 228, 299
69 ADRB2 [2] Renin secretion, Salivary secretion D05648 Pseudoephedrine [1] 17
70 ADRB2 [2] Renin secretion, Salivary secretion D05649 Pseudoephedrine [1] 17
71 ADRB2 [2] Renin secretion, Salivary secretion D05792 Salmeterol [1] 299
72 ADRB2 [2] Renin secretion, Salivary secretion D07713 Clenbuterol [5] 1, 2, 6, 13, 256
73 ADRB2 [2] Renin secretion, Salivary secretion D07990 Formoterol [3] 85, 228, 299
74 ADRB2 [2] Renin secretion, Salivary secretion D08092 Isoxsuprine [1] 13
75 ADRB2 [2] Renin secretion, Salivary secretion D08124 Levosalbutamol [1] 49
76 ADRB2 [2] Renin secretion, Salivary secretion D08443 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
77 ADRB2 [2] Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
78 ADRB2 [2] Renin secretion, Salivary secretion D08570 Terbutaline [1] 118
79 ADRB2 [2] Renin secretion, Salivary secretion D08600 Timolol [2] 157, 227
80 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00076 Norepinephrine [1] 22
81 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
82 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
83 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00483 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
84 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00485 Pseudoephedrine [1] 17
85 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00996 Epinephrine [3] 46, 70, 96
86 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
87 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D02149 Epinephrine [3] 46, 70, 96
88 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
89 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D05206 Norepinephrine [1] 22
90 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D05648 Pseudoephedrine [1] 17
91 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D05649 Pseudoephedrine [1] 17
92 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D08443 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
93 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
94 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D09535 Mirabegron [4] 6, 13, 53, 226
95 ACE [2] Renin-angiotensin system, Renin secretion D00251 Captopril [8] 6, 17, 46, 86, 96, 97, 107, 271
96 ACE [2] Renin-angiotensin system, Renin secretion D00362 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
97 ACE [2] Renin-angiotensin system, Renin secretion D00421 Ramipril [7] 46, 49, 66, 67, 113, 218, 257
98 ACE [2] Renin-angiotensin system, Renin secretion D00459 Quinapril [1] 19
99 ACE [2] Renin-angiotensin system, Renin secretion D00620 Benazepril [4] 49, 57, 218, 224
100 ACE [2] Renin-angiotensin system, Renin secretion D00621 Enalapril [6] 19, 46, 66, 113, 210, 222
101 ACE [2] Renin-angiotensin system, Renin secretion D00623 Moexipril [1] 93
102 ACE [2] Renin-angiotensin system, Renin secretion D00624 Perindopril [4] 58, 113, 167, 222
103 ACE [2] Renin-angiotensin system, Renin secretion D01069 Cilazapril [1] 66
104 ACE [2] Renin-angiotensin system, Renin secretion D03752 Quinapril [1] 19
105 ACE [2] Renin-angiotensin system, Renin secretion D03753 Perindopril [4] 58, 113, 167, 222
106 ACE [2] Renin-angiotensin system, Renin secretion D07499 Benazepril [4] 49, 57, 218, 224
107 ACE [2] Renin-angiotensin system, Renin secretion D07699 Cilazapril [1] 66
108 ACE [2] Renin-angiotensin system, Renin secretion D07892 Enalapril [6] 19, 46, 66, 113, 210, 222
109 ACE [2] Renin-angiotensin system, Renin secretion D08068 Imidapril [1] 67
110 ACE [2] Renin-angiotensin system, Renin secretion D08131 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
111 ACE [2] Renin-angiotensin system, Renin secretion D08225 Moexipril [1] 93
112 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
113 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00357 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
114 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
115 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00522 Candesartan cilexetil [1] 67
116 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00522 Candesartan [2] 58, 67
117 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00523 Irbesartan [4] 66, 167, 168, 222
118 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00626 Candesartan cilexetil [1] 67
119 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00627 Telmisartan [2] 66, 67
120 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
121 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D08146 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
122 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D11776 Sparsentan [3] 66, 218, 222
123 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D01227 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
124 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07077 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211
125 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07171 Sitaxentan [1] 86
126 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07538 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
127 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07741 Zibotentan [1] 51
128 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D10135 Macitentan [5] 51, 85, 86, 88, 210
129 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D11776 Sparsentan [3] 66, 218, 222
130 GUCY1A2 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
131 GUCY1A2 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
132 GUCY1A1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
133 GUCY1A1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
134 GUCY1B1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
135 GUCY1B1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
136 NPR1 [3] Vascular smooth muscle contraction, Thermogenesis, Renin secretion D04051 Erythrityl tetranitrate [1] 46
137 NPR1 [3] Vascular smooth muscle contraction, Thermogenesis, Renin secretion D05147 Nesiritide [2] 46, 58
138 PDE1A [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
139 PDE1A [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
140 PDE1A [2] Taste transduction, Renin secretion D00718 Flavoxate [1] 226
141 PDE1A [2] Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
142 PDE1A [2] Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
143 PDE1A [2] Taste transduction, Renin secretion D05429 Aminophylline [1] 63
144 PDE1A [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
145 PDE1A [2] Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
146 PDE1A [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
147 PDE1A [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
148 PDE1C [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
149 PDE1C [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
150 PDE1C [2] Taste transduction, Renin secretion D00718 Flavoxate [1] 226
151 PDE1C [2] Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
152 PDE1C [2] Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
153 PDE1C [2] Taste transduction, Renin secretion D05429 Aminophylline [1] 63
154 PDE1C [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
155 PDE1C [2] Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
156 PDE1C [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
157 PDE1C [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
158 PDE3A [1] Renin secretion D00227 Aminophylline [1] 63
159 PDE3A [1] Renin secretion D00371 Theophylline [2] 236, 299
160 PDE3A [1] Renin secretion D00417 Milrinone [1] 294
161 PDE3A [1] Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
162 PDE3A [1] Renin secretion D00718 Flavoxate [1] 226
163 PDE3A [1] Renin secretion D01385 Ibudilast [2] 2, 13
164 PDE3A [1] Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
165 PDE3A [1] Renin secretion D01712 Theophylline [2] 236, 299
166 PDE3A [1] Renin secretion D01896 Cilostazol [3] 51, 70, 124
167 PDE3A [1] Renin secretion D02017 Theophylline [2] 236, 299
168 PDE3A [1] Renin secretion D02085 Milrinone [1] 294
169 PDE3A [1] Renin secretion D04720 Levosimendan [1] 2
170 PDE3A [1] Renin secretion D05429 Aminophylline [1] 63
171 PDE3A [1] Renin secretion D06103 Theophylline [2] 236, 299
172 PDE3A [1] Renin secretion D06104 Theophylline [2] 236, 299
173 PDE3A [1] Renin secretion D07546 Bucladesine [1] 246
174 PDE3A [1] Renin secretion D07961 Flavoxate [1] 226
175 PDE3B [1] Renin secretion D00227 Aminophylline [1] 63
176 PDE3B [1] Renin secretion D00371 Theophylline [2] 236, 299
177 PDE3B [1] Renin secretion D00417 Milrinone [1] 294
178 PDE3B [1] Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
179 PDE3B [1] Renin secretion D00718 Flavoxate [1] 226
180 PDE3B [1] Renin secretion D01385 Ibudilast [2] 2, 13
181 PDE3B [1] Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
182 PDE3B [1] Renin secretion D01712 Theophylline [2] 236, 299
183 PDE3B [1] Renin secretion D01896 Cilostazol [3] 51, 70, 124
184 PDE3B [1] Renin secretion D02017 Theophylline [2] 236, 299
185 PDE3B [1] Renin secretion D02085 Milrinone [1] 294
186 PDE3B [1] Renin secretion D04720 Levosimendan [1] 2
187 PDE3B [1] Renin secretion D05429 Aminophylline [1] 63
188 PDE3B [1] Renin secretion D06103 Theophylline [2] 236, 299
189 PDE3B [1] Renin secretion D06104 Theophylline [2] 236, 299
190 PDE3B [1] Renin secretion D07546 Bucladesine [1] 246
191 PDE3B [1] Renin secretion D07961 Flavoxate [1] 226
192 PDE1B [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
193 PDE1B [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
194 PDE1B [2] Taste transduction, Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
195 PDE1B [2] Taste transduction, Renin secretion D00718 Flavoxate [1] 226
196 PDE1B [2] Taste transduction, Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
197 PDE1B [2] Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
198 PDE1B [2] Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
199 PDE1B [2] Taste transduction, Renin secretion D05429 Aminophylline [1] 63
200 PDE1B [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
201 PDE1B [2] Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
202 PDE1B [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
203 PDE1B [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
204 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
205 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
206 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
207 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
208 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [1] 222
209 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
210 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
211 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
212 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
213 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [1] 222
214 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
215 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
216 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
217 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
218 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [1] 222
219 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
220 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
221 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
222 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
223 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [1] 222
224 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
225 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
226 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
227 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
228 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [1] 222
229 PTGER2 [1] Renin secretion D00419 Misoprostol [3] 46, 70, 271
230 PTGER4 [1] Renin secretion D00419 Misoprostol [3] 46, 70, 271
231 REN [2] Renin-angiotensin system, Renin secretion D03208 Aliskiren [3] 66, 167, 222
232 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00349 Isradipine [1] 6
233 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
234 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
235 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
236 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
237 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
238 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
239 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D01173 Cilnidipine [1] 67
240 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D01908 Nilvadipine [1] 90
241 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
242 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
243 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
244 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
245 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
246 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
247 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
248 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
249 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08441 Propiverine [1] 226
250 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00349 Isradipine [1] 6
251 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
252 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
253 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
254 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
255 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
256 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
257 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D01173 Cilnidipine [1] 67
258 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D01908 Nilvadipine [1] 90
259 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
260 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
261 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
262 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
263 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
264 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
265 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
266 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
267 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08441 Propiverine [1] 226
268 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00349 Isradipine [1] 6
269 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00437 Nifedipine [2] 50, 81
270 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
271 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00615 Amlodipine [4] 13, 51, 67, 298
272 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00616 Diltiazem [3] 51, 58, 86
273 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00617 Nicardipine [2] 70, 86
274 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00619 Verapamil [3] 96, 140, 167
275 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01173 Cilnidipine [1] 67
276 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01908 Nilvadipine [1] 90
277 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02356 Verapamil [3] 96, 140, 167
278 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02914 Amlodipine [4] 13, 51, 67, 298
279 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D03830 Diltiazem [3] 51, 58, 86
280 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D05442 Perhexiline [2] 58, 272
281 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07450 Amlodipine [4] 13, 51, 67, 298
282 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07845 Diltiazem [3] 51, 58, 86
283 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08270 Nicardipine [2] 70, 86
284 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08340 Perhexiline [2] 58, 272
285 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08441 Propiverine [1] 226
286 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00349 Isradipine [1] 6
287 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00437 Nifedipine [2] 50, 81
288 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
289 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00615 Amlodipine [4] 13, 51, 67, 298
290 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00616 Diltiazem [3] 51, 58, 86
291 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00617 Nicardipine [2] 70, 86
292 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00619 Verapamil [3] 96, 140, 167
293 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01173 Cilnidipine [1] 67
294 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01908 Nilvadipine [1] 90
295 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02356 Verapamil [3] 96, 140, 167
296 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02914 Amlodipine [4] 13, 51, 67, 298
297 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D03830 Diltiazem [3] 51, 58, 86
298 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D05442 Perhexiline [2] 58, 272
299 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07450 Amlodipine [4] 13, 51, 67, 298
300 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07845 Diltiazem [3] 51, 58, 86
301 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08270 Nicardipine [2] 70, 86
302 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08340 Perhexiline [2] 58, 272
303 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08441 Propiverine [1] 226