Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
3 HLA-DMA [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
4 HLA-DMB [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
5 HLA-DOA [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
6 HLA-DOB [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
7 HLA-DPA1 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
8 HLA-DPB1 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
9 HLA-DQA1 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
10 HLA-DQA2 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
11 HLA-DQB1 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
12 HLA-DRA [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
13 HLA-DRB1 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
14 HLA-DRB3 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
15 HLA-DRB4 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
16 HLA-DRB5 [3] Type I diabetes mellitus, Tuberculosis, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
17 IFNA1 [1] Tuberculosis D09662 Rontalizumab [1] 49
18 IFNA1 [1] Tuberculosis D09668 Sifalimumab [1] 49
19 IFNA2 [1] Tuberculosis D09662 Rontalizumab [1] 49
20 IFNA2 [1] Tuberculosis D09668 Sifalimumab [1] 49
21 IFNA4 [1] Tuberculosis D09662 Rontalizumab [1] 49
22 IFNA4 [1] Tuberculosis D09668 Sifalimumab [1] 49
23 IFNA5 [1] Tuberculosis D09662 Rontalizumab [1] 49
24 IFNA5 [1] Tuberculosis D09668 Sifalimumab [1] 49
25 IFNA6 [1] Tuberculosis D09662 Rontalizumab [1] 49
26 IFNA6 [1] Tuberculosis D09668 Sifalimumab [1] 49
27 IFNA7 [1] Tuberculosis D09662 Rontalizumab [1] 49
28 IFNA7 [1] Tuberculosis D09668 Sifalimumab [1] 49
29 IFNA8 [1] Tuberculosis D09662 Rontalizumab [1] 49
30 IFNA8 [1] Tuberculosis D09668 Sifalimumab [1] 49
31 IFNA10 [1] Tuberculosis D09662 Rontalizumab [1] 49
32 IFNA10 [1] Tuberculosis D09668 Sifalimumab [1] 49
33 IFNA13 [1] Tuberculosis D09662 Rontalizumab [1] 49
34 IFNA13 [1] Tuberculosis D09668 Sifalimumab [1] 49
35 IFNA14 [1] Tuberculosis D09662 Rontalizumab [1] 49
36 IFNA14 [1] Tuberculosis D09668 Sifalimumab [1] 49
37 IFNA16 [1] Tuberculosis D09662 Rontalizumab [1] 49
38 IFNA16 [1] Tuberculosis D09668 Sifalimumab [1] 49
39 IFNA17 [1] Tuberculosis D09662 Rontalizumab [1] 49
40 IFNA17 [1] Tuberculosis D09668 Sifalimumab [1] 49
41 IFNA21 [1] Tuberculosis D09662 Rontalizumab [1] 49
42 IFNA21 [1] Tuberculosis D09668 Sifalimumab [1] 49
43 IFNG [2] Type I diabetes mellitus, Tuberculosis D04242 Fontolizumab [1] 46
44 IFNG [2] Type I diabetes mellitus, Tuberculosis D11120 Emapalumab [2] 49, 107
45 IFNGR1 [1] Tuberculosis D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
46 IFNGR2 [1] Tuberculosis D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
47 IL1A [2] Type I diabetes mellitus, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
48 IL1A [2] Type I diabetes mellitus, Tuberculosis D06635 Rilonacept [4] 51, 106, 107, 266
49 IL1A [2] Type I diabetes mellitus, Tuberculosis D11253 Bermekimab [1] 51
50 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
51 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D06635 Rilonacept [4] 51, 106, 107, 266
52 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
53 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D09911 Gevokizumab [4] 41, 50, 56, 269
54 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
55 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
56 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D09669 Siltuximab [2] 28, 331
57 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D10080 Sirukumab [2] 41, 46
58 IL10 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
59 IL12A [2] Type I diabetes mellitus, Tuberculosis D09214 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
60 IL12B [2] Type I diabetes mellitus, Tuberculosis D09214 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
61 JAK1 [2] Tuberculosis, Viral carcinogenesis D09959 Ruxolitinib [1] 228
62 JAK1 [2] Tuberculosis, Viral carcinogenesis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
63 JAK1 [2] Tuberculosis, Viral carcinogenesis D10308 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
64 JAK1 [2] Tuberculosis, Viral carcinogenesis D10653 Peficitinib [1] 46
65 JAK1 [2] Tuberculosis, Viral carcinogenesis D10871 Filgotinib [6] 46, 53, 96, 97, 222, 271
66 JAK1 [2] Tuberculosis, Viral carcinogenesis D10944 Itacitinib [5] 46, 51, 60, 97, 228
67 JAK1 [2] Tuberculosis, Viral carcinogenesis D10994 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271
68 JAK2 [1] Tuberculosis D09959 Ruxolitinib [1] 228
69 JAK2 [1] Tuberculosis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
70 JAK2 [1] Tuberculosis D10308 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
71 JAK2 [1] Tuberculosis D10653 Peficitinib [1] 46
72 NFKB1 [3] Yersinia infection, Tuberculosis, Viral carcinogenesis D01146 Iguratimod [4] 46, 51, 53, 271
73 IL23A [1] Tuberculosis D09214 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
74 IL23A [1] Tuberculosis D10400 Tildrakizumab [2] 162, 271
75 IL23A [1] Tuberculosis D10438 Guselkumab [5] 37, 41, 51, 96, 97
76 IL23A [1] Tuberculosis D10912 Brazikumab [2] 96, 97
77 IL23A [1] Tuberculosis D11052 Risankizumab [4] 37, 96, 97, 271
78 IL23A [1] Tuberculosis D11123 Mirikizumab [3] 37, 96, 97
79 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
80 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
81 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
82 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
83 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [1] 222
84 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
85 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
86 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
87 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
88 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [1] 222
89 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
90 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
91 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
92 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
93 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [1] 222
94 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
95 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
96 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
97 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
98 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [1] 222
99 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
100 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
101 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
102 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
103 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [1] 222
104 MAPK11 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
105 MAPK11 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
106 MAPK13 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
107 MAPK13 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
108 RAF1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Tuberculosis D06272 Sorafenib [2] 34, 86
109 RAF1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
110 BCL2 [1] Tuberculosis D10679 Venetoclax [1] 28
111 RELA [3] Yersinia infection, Tuberculosis, Viral carcinogenesis D12181 Edasalonexent [1] 113
112 MAPK12 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
113 MAPK12 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
114 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
115 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
116 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
117 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
118 SYK [2] Tuberculosis, Viral carcinogenesis D09347 Fostamatinib [4] 46, 49, 61, 66
119 TGFB1 [1] Tuberculosis D09620 Fresolimumab [4] 51, 85, 222, 274
120 TGFB2 [1] Tuberculosis D09620 Fresolimumab [4] 51, 85, 222, 274
121 TGFB3 [1] Tuberculosis D09620 Fresolimumab [4] 51, 85, 222, 274
122 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
123 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
124 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
125 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
126 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
127 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
128 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
129 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
130 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D05393 Pegsunercept [1] 46
131 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
132 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D09944 Ozoralizumab [1] 46
133 C3 [2] Tuberculosis, Viral carcinogenesis D11613 Pegcetacoplan [3] 2, 62, 222
134 VDR [1] Tuberculosis D00122 Calcifediol [2] 113, 299
135 VDR [1] Tuberculosis D00129 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326
136 VDR [1] Tuberculosis D00187 Ergocalciferol [6] 46, 49, 84, 96, 97, 299
137 VDR [1] Tuberculosis D00188 Cholecalciferol [25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
138 VDR [1] Tuberculosis D00299 Dihydrotachysterol [2] 6, 85
139 VDR [1] Tuberculosis D00930 Paricalcitol [4] 19, 66, 218, 238
140 VDR [1] Tuberculosis D01125 Calcipotriol [2] 36, 51
141 VDR [1] Tuberculosis D01518 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238
142 VDR [1] Tuberculosis D07578 Eldecalcitol [1] 46
143 CASP9 [3] VEGF signaling pathway, Tuberculosis, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
144 CD74 [1] Tuberculosis D08944 Milatuzumab [1] 49