1 |
DHODH
💬
| [3] Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Leflunomide
Leflunomide
💬
|
Leflunomide
| [12] 11 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
2 |
DHODH
💬
| [3] Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Teriflunomide
Teriflunomide
💬
|
Teriflunomide
| [3] 13 13, 25, 26 💬 |
3 |
RRM1
💬
| [6] Purine metabolism Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism | Cladribine
Cladribine
💬
|
Cladribine
| [3] 11 11, 13, 94 💬 |
4 |
RRM1
💬
| [6] Purine metabolism Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism | Clofarabine
Clofarabine
💬
|
Clofarabine
| [5] 19 19, 20, 60, 234, 326 💬 |
5 |
RRM1
💬
| [6] Purine metabolism Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism | Fludarabine
Fludarabine
💬
|
Fludarabine
| [20] 11 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
6 |
RRM2
💬
| [7] Purine metabolism Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, p53 signaling pathway | Hydroxyurea
Hydroxyurea
💬
|
Hydroxyurea
| [8] 3 3, 13, 19, 20, 65, 85, 86, 284 💬 |
7 |
TYMS
💬
| [5] Pyrimidine metabolism Pyrimidine metabolism, One carbon pool by folate, Metabolic pathways, Nucleotide metabolism, Antifolate resistance | Tegafur
Tegafur
💬
|
Tegafur
| [1] 46 46 💬 |