Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬 💬
2 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬 💬
3 Purine metabolism 💬
 [1] GUCY2C 💬 Linaclotide 💬 Linaclotide [2]  6 , 97 💬 💬
4 Purine metabolism 💬
 [1] HPRT1 💬 Mercaptopurine 💬 Mercaptopurine [4] 65, 96, 97, 164 💬 💬
5 Purine metabolism 💬
 [1] HPRT1 💬 Mercaptopurine 💬 Mercaptopurine [4] 65, 96, 97, 164 💬 💬
6 Purine metabolism 💬
 [1] HPRT1 💬 Tioguanine 💬 Tioguanine [2] 13, 37 💬 💬
7 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 Mizoribine 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬 💬
8 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 Mycophenolate mofetil 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬
9 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 Mycophenolic acid 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬
10 Purine metabolism 💬
 [1] NPR1 💬 Nesiritide 💬 Nesiritide [2] 46, 58 💬 💬
11 Purine metabolism 💬
 [2] NPR1, NPR2 💬 Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬 💬
12 Purine metabolism 💬
 [1] NPR2 💬 Vosoritide 💬 Vosoritide [1] 276 💬 💬
13 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬 💬
14 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬 💬
15 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬 💬
16 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
17 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
18 Purine metabolism 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
19 Purine metabolism 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
20 Purine metabolism 💬
 [2] PDE3A, PDE3B 💬 Cilostazol 💬 Cilostazol [3] 46, 51, 70 💬 💬
21 Purine metabolism 💬
 [2] PDE3A, PDE3B 💬 Levosimendan 💬 Levosimendan [1]  2  💬 💬
22 Purine metabolism 💬
 [2] PDE3A, PDE3B 💬 Milrinone 💬 Milrinone [1] 294 💬 💬
23 Purine metabolism 💬
 [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬 💬
24 Purine metabolism 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Apremilast 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬 💬
25 Purine metabolism 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
26 Purine metabolism 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Rolipram 💬 Rolipram [2]  8 , 13 💬 💬
27 Purine metabolism 💬
 [2] PDE4A, PDE5A 💬 Dipyridamole 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬 💬
28 Purine metabolism 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
29 Purine metabolism 💬
 [1] PDE5A 💬 Sildenafil 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬
30 Purine metabolism 💬
 [1] PDE5A 💬 Tadalafil 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬 💬
31 Purine metabolism 💬
 [1] PDE5A 💬 Udenafil 💬 Udenafil [2] 86, 210 💬 💬
32 Purine metabolism 💬
 [1] PDE5A 💬 Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬 💬
33 Purine metabolism 💬
 [1] RRM1 💬 Cladribine 💬 Cladribine [3] 11, 13, 94 💬 💬
34 Purine metabolism 💬
 [1] RRM1 💬 Clofarabine 💬 Clofarabine [5] 19, 20, 60, 234, 326 💬 💬
35 Purine metabolism 💬
 [1] RRM1 💬 Fludarabine 💬 Fludarabine [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬
36 Purine metabolism 💬
 [1] RRM2 💬 Hydroxyurea 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬 💬
37 Purine metabolism 💬
 [1] XDH 💬 Allopurinol 💬 Allopurinol [7]  6 , 46, 57, 60, 66, 96, 97 💬 💬
38 Purine metabolism 💬
 [1] XDH 💬 Febuxostat 💬 Febuxostat [3]  2 ,  6 , 13 💬 💬