Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

[5] 5 , 6 , 17, 169, 170 💬

2

AMPK signaling pathway 💬

[1] ADRA1A 💬

[5] 5 , 6 , 17, 169, 170 💬

3

Calcium signaling pathway 💬

[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬

[5] 5 , 6 , 17, 169, 170 💬

4

cAMP signaling pathway 💬

[2] ADRB1, ADRB2 💬

[5] 5 , 6 , 17, 169, 170 💬

5

cGMP-PKG signaling pathway 💬

[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	adrenoceptor alpha 1A
ADRA1B	adrenoceptor alpha 1B
ADRA1D	adrenoceptor alpha 1D
ADRA2A	adrenoceptor alpha 2A
ADRA2B	adrenoceptor alpha 2B
ADRA2C	adrenoceptor alpha 2C
ADRB1	adrenoceptor beta 1
ADRB2	adrenoceptor beta 2
ADRB3	adrenoceptor beta 3

[5] 5 , 6 , 17, 169, 170 💬

6

Chemical carcinogenesis - receptor activation 💬

[3] ADRB1, ADRB2, ADRB3 💬

[5] 5 , 6 , 17, 169, 170 💬

7

Dilated cardiomyopathy 💬

[1] ADRB1 💬

[5] 5 , 6 , 17, 169, 170 💬

8

Gap junction 💬

[1] ADRB1 💬

[5] 5 , 6 , 17, 169, 170 💬

9

Neuroactive ligand-receptor interaction 💬

[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	adrenoceptor alpha 1A
ADRA1B	adrenoceptor alpha 1B
ADRA1D	adrenoceptor alpha 1D
ADRA2A	adrenoceptor alpha 2A
ADRA2B	adrenoceptor alpha 2B
ADRA2C	adrenoceptor alpha 2C
ADRB1	adrenoceptor beta 1
ADRB2	adrenoceptor beta 2
ADRB3	adrenoceptor beta 3

[5] 5 , 6 , 17, 169, 170 💬

10

Regulation of lipolysis in adipocytes 💬

[3] ADRB1, ADRB2, ADRB3 💬

[5] 5 , 6 , 17, 169, 170 💬

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