Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
2 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
3 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
4 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
5 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
6 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Brazikumab Brazikumab 💬 |
Brazikumab | 096 [2] 96, 97 💬 💬 |
7 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
8 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
9 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
10 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Tildrakizumab Tildrakizumab 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 💬 |
11 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
12 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
13 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
14 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
15 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
16 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
17 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
18 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
19 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
20 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
21 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
22 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
23 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
24 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
25 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
26 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PRKCD [1] PRKCD 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
27 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
28 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
29 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
30 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
31 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
32 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
33 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
34 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
35 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
36 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
37 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
38 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
39 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
40 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
41 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
42 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
43 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
44 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
45 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
46 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
47 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
48 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
49 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
50 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
51 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
52 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
53 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
54 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
55 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
56 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
57 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SYK [1] SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 💬 |
58 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
59 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
60 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
61 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
62 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
63 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
64 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
65 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
66 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
67 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
68 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬 |
Febuxostat Febuxostat 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 💬 |
69 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [1] ADORA2A 💬 |
Istradefylline Istradefylline 💬 |
Istradefylline | 006 [1] 6 💬 💬 |
70 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [1] ADORA2A 💬 |
Preladenant Preladenant 💬 |
Preladenant | 006 [1] 6 💬 💬 |
71 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
72 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
73 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [1] ADORA2A 💬 |
Tozadenant Tozadenant 💬 |
Tozadenant | 006 [1] 6 💬 💬 |
74 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
Adenosine Adenosine 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 💬 |
75 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
Adenosine phosphate Adenosine phosphate 💬 |
Adenosine phosphate | 046 [1] 46 💬 💬 |
76 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
77 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
78 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
79 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
80 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
81 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [1] ADRA1A 💬 |
Alfuzosin Alfuzosin 💬 |
Alfuzosin | 013 [1] 13 💬 💬 |
82 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [1] ADRA1A 💬 |
Silodosin Silodosin 💬 |
Silodosin | 006 [2] 6 , 13 💬 💬 |
83 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
84 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Methylergometrine Methylergometrine 💬 |
Methylergometrine | 280 [1] 280 💬 💬 |
85 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Midodrine Midodrine 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 💬 |
86 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Phenylephrine Phenylephrine 💬 |
Phenylephrine | 022 [1] 22 💬 💬 |
87 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Tamsulosin Tamsulosin 💬 |
Tamsulosin | 013 [1] 13 💬 💬 |
88 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Terazosin Terazosin 💬 |
Terazosin | 006 [1] 6 💬 💬 |
89 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
90 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
91 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Dipivefrin Dipivefrin 💬 |
Dipivefrin | 006 [1] 6 💬 💬 |
92 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Droxidopa Droxidopa 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 💬 |
93 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Ephedrine Ephedrine 💬 |
Ephedrine | 011 [1] 11 💬 💬 |
94 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Epinephrine Epinephrine 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 💬 |
95 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Noradrenaline Noradrenaline 💬 |
Norepinephrine | 022 [2] 22, 296 💬 💬 |
96 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
Pseudoephedrine Pseudoephedrine 💬 |
Pseudoephedrine | 017 [1] 17 💬 💬 |
97 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
Olanzapine Olanzapine 💬 |
Olanzapine | 002 [2] 2 , 8 💬 💬 |
98 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Atenolol Atenolol 💬 |
Atenolol | 167 [1] 167 💬 💬 |
99 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Bisoprolol Bisoprolol 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 💬 |
100 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Celiprolol Celiprolol 💬 |
Celiprolol | 168 [1] 168 💬 💬 |
101 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
102 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Esmolol Esmolol 💬 |
Esmolol | 058 [1] 58 💬 💬 |
103 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
104 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Nebivolol Nebivolol 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 💬 |
105 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Nadolol Nadolol 💬 |
Nadolol | 006 [1] 6 💬 💬 |
106 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
107 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
108 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Propranolol Propranolol 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 💬 |
109 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Clenbuterol Clenbuterol 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 💬 |
110 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Formoterol Formoterol 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 💬 |
111 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Isoxsuprine Isoxsuprine 💬 |
Isoxsuprine | 013 [1] 13 💬 💬 |
112 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Levosalbutamol Levosalbutamol 💬 |
Levosalbutamol | 049 [1] 49 💬 💬 |
113 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
114 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Salmeterol Salmeterol 💬 |
Salmeterol | 299 [1] 299 💬 💬 |
115 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Terbutaline Terbutaline 💬 |
Terbutaline | 118 [1] 118 💬 💬 |
116 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Tulobuterol Tulobuterol 💬 |
Tulobuterol | 006 [1] 6 💬 💬 |
117 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB3 [1] ADRB3 💬 |
Mirabegron Mirabegron 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 💬 |
118 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
119 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
120 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
121 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
122 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
123 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
124 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
125 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
126 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [2] AGTR1, EDNRA 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
127 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AVPR1A [1] AVPR1A 💬 |
Conivaptan Conivaptan 💬 |
Conivaptan | 086 [1] 86 💬 💬 |
128 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
Terlipressin Terlipressin 💬 |
Terlipressin | 299 [1] 299 💬 💬 |
129 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
Vasopressin Vasopressin 💬 |
Vasopressin | 210 [1] 210 💬 💬 |
130 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
131 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
132 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
133 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
134 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
135 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
136 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
137 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
138 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
139 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
140 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
141 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Flunarizine Flunarizine 💬 |
Flunarizine | 149 [1] 149 💬 💬 |
142 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
143 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Zonisamide Zonisamide 💬 |
Zonisamide | 006 [1] 6 💬 💬 |
144 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CCKBR [1] CCKBR 💬 |
Proglumide Proglumide 💬 |
Proglumide | 298 [1] 298 💬 💬 |
145 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 [1] CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬 💬 |
146 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 [1] CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 [3] 28, 61, 283 💬 💬 |
147 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 [1] CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 [2] 63, 66 💬 💬 |
148 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
149 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
150 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
151 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
152 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
153 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
154 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
155 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
156 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
157 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM3 [1] CHRM3 💬 |
Cevimeline Cevimeline 💬 |
Cevimeline | 053 [1] 53 💬 💬 |
158 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM3 [1] CHRM3 💬 |
Darifenacin Darifenacin 💬 |
Darifenacin | 006 [2] 6 , 13 💬 💬 |
159 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM3 [1] CHRM3 💬 |
Solifenacin Solifenacin 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 💬 |
160 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM3 [1] CHRM3 💬 |
Tolterodine Tolterodine 💬 |
Tolterodine | 017 [2] 17, 53 💬 💬 |
161 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRNA7 [1] CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 💬 |
162 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CXCR4 [1] CXCR4 💬 |
Plerixafor Plerixafor 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 💬 |
163 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
164 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
Montelukast Montelukast 💬 |
Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬 💬 |
165 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
Tipelukast Tipelukast 💬 |
Tipelukast | 085 [1] 85 💬 💬 |
166 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [1] DRD1 💬 |
Apomorphine Apomorphine 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 💬 |
167 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [1] DRD1 💬 |
Flupentixol Flupentixol 💬 |
Flupentixol | 097 [1] 97 💬 💬 |
168 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [1] DRD1 💬 |
Pergolide Pergolide 💬 |
Pergolide | 006 [1] 6 💬 💬 |
169 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Dexpramipexole Dexpramipexole 💬 |
Dexpramipexole | 002 [1] 2 💬 💬 |
170 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Dopamine Dopamine 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 💬 |
171 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Foslevodopa Foslevodopa 💬 |
Foslevodopa | 006 [1] 6 💬 💬 |
172 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
173 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Tavapadon Tavapadon 💬 |
Tavapadon | 006 [1] 6 💬 💬 |
174 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
175 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬 |
Sitaxentan Sitaxentan 💬 |
Sitaxentan | 086 [1] 86 💬 💬 |
176 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬 |
Zibotentan Zibotentan 💬 |
Zibotentan | 051 [1] 51 💬 💬 |
177 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
178 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
179 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Macitentan Macitentan 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 💬 |
180 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
181 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
182 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
183 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
184 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
185 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
186 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
187 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
188 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
189 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
190 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
191 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Axitinib Axitinib 💬 |
Axitinib | 034 [1] 34 💬 💬 |
192 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Cediranib Cediranib 💬 |
Cediranib | 034 [1] 34 💬 💬 |
193 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
194 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
195 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
196 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
197 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
198 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
199 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
200 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
201 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
202 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
203 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Cetirizine Cetirizine 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 💬 |
204 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Chlorphenamine Chlorphenamine 💬 |
Chlorpheniramine | 014 [1] 14 💬 💬 |
205 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Clemastine Clemastine 💬 |
Clemastine | 013 [1] 13 💬 💬 |
206 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Desloratadine Desloratadine 💬 |
Desloratadine | 013 [1] 13 💬 💬 |
207 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Dexchlorpheniramine Dexchlorpheniramine 💬 |
Dexchlorpheniramine | 013 [2] 13, 49 💬 💬 |
208 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Diphenhydramine Diphenhydramine 💬 |
Diphenhydramine | 011 [8] 11, 13, 49, 51, 70, 86, 222, 256 💬 💬 |
209 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Doxepin Doxepin 💬 |
Doxepin | 006 [1] 6 💬 💬 |
210 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Fexofenadine Fexofenadine 💬 |
Fexofenadine | 013 [2] 13, 46 💬 💬 |
211 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Levocetirizine Levocetirizine 💬 |
Levocetirizine | 061 [1] 61 💬 💬 |
212 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Loratadine Loratadine 💬 |
Loratadine | 013 [4] 13, 46, 89, 98 💬 💬 |
213 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Promethazine Promethazine 💬 |
Promethazine | 096 [1] 96 💬 💬 |
214 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [2] HRH1, PTAFR 💬 |
Rupatadine Rupatadine 💬 |
Rupatadine | 046 [1] 46 💬 💬 |
215 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬 |
Cimetidine Cimetidine 💬 |
Cimetidine | 002 [2] 2 , 254 💬 💬 |
216 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬 |
Famotidine Famotidine 💬 |
Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬 💬 |
217 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬 |
Ranitidine Ranitidine 💬 |
Ranitidine | 013 [2] 13, 65 💬 💬 |
218 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬 |
Aripiprazole Aripiprazole 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 💬 |
219 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬 |
Cariprazine Cariprazine 💬 |
Cariprazine | 021 [1] 21 💬 💬 |
220 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬 |
Nelotanserin Nelotanserin 💬 |
Nelotanserin | 006 [1] 6 💬 💬 |
221 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬 |
Quetiapine Quetiapine 💬 |
Quetiapine | 006 [2] 6 , 13 💬 💬 |
222 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬 |
Risperidone Risperidone 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 💬 |
223 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
Iloperidone Iloperidone 💬 |
Iloperidone | 006 [1] 6 💬 💬 |
224 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
Trazodone Trazodone 💬 |
Trazodone | 002 [1] 2 💬 💬 |
225 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [2] HTR2A, HTR2C 💬 |
Clozapine Clozapine 💬 |
Clozapine | 006 [1] 6 💬 💬 |
226 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [2] HTR2A, HTR2C 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
227 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [2] HTR2A, HTR4 💬 |
Cisapride Cisapride 💬 |
Cisapride | 013 [1] 13 💬 💬 |
228 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [2] HTR2A, HTR4 💬 |
Cisapride Cisapride 💬 |
Cisapride | 013 [1] 13 💬 💬 |
229 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2C [1] HTR2C 💬 |
Agomelatine Agomelatine 💬 |
Agomelatine | 006 [1] 6 💬 💬 |
230 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR4 [1] HTR4 💬 |
Mosapride Mosapride 💬 |
Mosapride | 096 [1] 96 💬 💬 |
231 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR4 [1] HTR4 💬 |
Prucalopride Prucalopride 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 💬 |
232 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR4 [1] HTR4 💬 |
Velusetrag Velusetrag 💬 |
Velusetrag | 099 [1] 99 💬 💬 |
233 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
KDR [2] KDR, MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
234 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
NGF [1] NGF 💬 |
Tanezumab Tanezumab 💬 |
Tanezumab | 226 [2] 226, 298 💬 💬 |
235 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
OXTR [1] OXTR 💬 |
Atosiban Atosiban 💬 |
Atosiban | 118 [1] 118 💬 💬 |
236 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
OXTR [1] OXTR 💬 |
Oxytocin Oxytocin 💬 |
Oxytocin | 006 [7] 6 , 72, 127, 168, 193, 206, 226 💬 💬 |
237 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
P2RX3 [1] P2RX3 💬 |
Gefapixant Gefapixant 💬 |
Gefapixant | 085 [2] 85, 226 💬 💬 |
238 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
239 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
240 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
241 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
242 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
243 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
244 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
245 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
246 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
247 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
248 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
249 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
250 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PTGER1 [1] PTGER1 💬 |
Alprostadil Alprostadil 💬 |
Alprostadil | 051 [2] 51, 70 💬 💬 |
251 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PTGER1 [1] PTGER1 💬 |
Limaprost Limaprost 💬 |
Limaprost | 070 [1] 70 💬 💬 |
252 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PTGER3 [1] PTGER3 💬 |
Misoprostol Misoprostol 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 💬 |
253 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PTGFR [1] PTGFR 💬 |
Tafluprost Tafluprost 💬 |
Tafluprost | 299 [1] 299 💬 💬 |
254 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PTGFR [1] PTGFR 💬 |
Unoprostone Unoprostone 💬 |
Unoprostone | 090 [1] 90 💬 💬 |
255 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TACR1 [1] TACR1 💬 |
Orvepitant Orvepitant 💬 |
Orvepitant | 085 [1] 85 💬 💬 |
256 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TACR1 [1] TACR1 💬 |
Serlopitant Serlopitant 💬 |
Serlopitant | 036 [1] 36 💬 💬 |
257 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TBXA2R [1] TBXA2R 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
258 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TBXA2R [1] TBXA2R 💬 |
Ifetroban Ifetroban 💬 |
Ifetroban | 085 [2] 85, 113 💬 💬 |
259 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TBXA2R [1] TBXA2R 💬 |
Ramatroban Ramatroban 💬 |
Ramatroban | 013 [1] 13 💬 💬 |
260 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TNNC2 [1] TNNC2 💬 |
Reldesemtiv Reldesemtiv 💬 |
Reldesemtiv | 002 [2] 2 , 3 💬 💬 |
261 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TRHR [1] TRHR 💬 |
Protirelin Protirelin 💬 |
Protirelin | 080 [1] 80 💬 💬 |
262 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
263 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
264 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [2] VEGFA, VEGFB 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
265 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
Adenosine Adenosine 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 💬 |
266 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
Adenosine phosphate Adenosine phosphate 💬 |
Adenosine phosphate | 046 [1] 46 💬 💬 |
267 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
268 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
269 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
270 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
271 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
272 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA2A [1] ADORA2A 💬 |
Istradefylline Istradefylline 💬 |
Istradefylline | 006 [1] 6 💬 💬 |
273 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA2A [1] ADORA2A 💬 |
Preladenant Preladenant 💬 |
Preladenant | 006 [1] 6 💬 💬 |
274 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
275 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
276 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA2A [1] ADORA2A 💬 |
Tozadenant Tozadenant 💬 |
Tozadenant | 006 [1] 6 💬 💬 |
277 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
278 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Atenolol Atenolol 💬 |
Atenolol | 167 [1] 167 💬 💬 |
279 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Bisoprolol Bisoprolol 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 💬 |
280 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Celiprolol Celiprolol 💬 |
Celiprolol | 168 [1] 168 💬 💬 |
281 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
282 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Esmolol Esmolol 💬 |
Esmolol | 058 [1] 58 💬 💬 |
283 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
284 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Nebivolol Nebivolol 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 💬 |
285 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
286 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Dipivefrin Dipivefrin 💬 |
Dipivefrin | 006 [1] 6 💬 💬 |
287 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Droxidopa Droxidopa 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 💬 |
288 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Ephedrine Ephedrine 💬 |
Ephedrine | 011 [1] 11 💬 💬 |
289 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Epinephrine Epinephrine 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 💬 |
290 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Nadolol Nadolol 💬 |
Nadolol | 006 [1] 6 💬 💬 |
291 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Noradrenaline Noradrenaline 💬 |
Norepinephrine | 022 [2] 22, 296 💬 💬 |
292 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Propranolol Propranolol 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 💬 |
293 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Pseudoephedrine Pseudoephedrine 💬 |
Pseudoephedrine | 017 [1] 17 💬 💬 |
294 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
295 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
296 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Clenbuterol Clenbuterol 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 💬 |
297 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Formoterol Formoterol 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 💬 |
298 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Isoxsuprine Isoxsuprine 💬 |
Isoxsuprine | 013 [1] 13 💬 💬 |
299 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Levosalbutamol Levosalbutamol 💬 |
Levosalbutamol | 049 [1] 49 💬 💬 |
300 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
301 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Salmeterol Salmeterol 💬 |
Salmeterol | 299 [1] 299 💬 💬 |
302 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Terbutaline Terbutaline 💬 |
Terbutaline | 118 [1] 118 💬 💬 |
303 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Tulobuterol Tulobuterol 💬 |
Tulobuterol | 006 [1] 6 💬 💬 |
304 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
305 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
306 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
307 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
308 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
309 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
310 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
311 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
312 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
313 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
314 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
315 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
316 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
317 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
318 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
319 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Deutivacaftor Deutivacaftor 💬 |
Deutivacaftor | 299 [1] 299 💬 💬 |
320 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Elexacaftor Elexacaftor 💬 |
Elexacaftor | 299 [1] 299 💬 💬 |
321 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Galicaftor Galicaftor 💬 |
Galicaftor | 299 [1] 299 💬 💬 |
322 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Ivacaftor Ivacaftor 💬 |
Ivacaftor | 299 [1] 299 💬 💬 |
323 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Lumacaftor Lumacaftor 💬 |
Lumacaftor | 299 [1] 299 💬 💬 |
324 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CFTR [1] CFTR 💬 |
Tezacaftor Tezacaftor 💬 |
Tezacaftor | 299 [1] 299 💬 💬 |
325 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
326 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
327 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
328 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
329 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
330 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
331 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
332 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM2 [1] CHRM2 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
333 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM2 [1] CHRM2 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
334 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CRHR1 [2] CRHR1, CRHR2 💬 |
Corticorelin Corticorelin 💬 |
Corticorelin | 075 [1] 75 💬 💬 |
335 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CRHR1 [2] CRHR1, CRHR2 💬 |
Corticorelin ovine triflutate Corticorelin ovine triflutate 💬 |
Corticorelin ovine triflutate | 075 [1] 75 💬 💬 |
336 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Apomorphine Apomorphine 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 💬 |
337 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Flupentixol Flupentixol 💬 |
Flupentixol | 097 [1] 97 💬 💬 |
338 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Pergolide Pergolide 💬 |
Pergolide | 006 [1] 6 💬 💬 |
339 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
Dexpramipexole Dexpramipexole 💬 |
Dexpramipexole | 002 [1] 2 💬 💬 |
340 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
Dopamine Dopamine 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 💬 |
341 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
Foslevodopa Foslevodopa 💬 |
Foslevodopa | 006 [1] 6 💬 💬 |
342 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
343 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Tavapadon Tavapadon 💬 |
Tavapadon | 006 [1] 6 💬 💬 |
344 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
345 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
346 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Domperidone Domperidone 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
347 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Domperidone maleate Domperidone maleate 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
348 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Haloperidol Haloperidol 💬 |
Haloperidol | 008 [1] 8 💬 💬 |
349 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Iloperidone Iloperidone 💬 |
Iloperidone | 006 [1] 6 💬 💬 |
350 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Lisuride Lisuride 💬 |
Lisuride | 006 [2] 6 , 86 💬 💬 |
351 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Melperone Melperone 💬 |
Melperone | 006 [1] 6 💬 💬 |
352 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Metoclopramide Metoclopramide 💬 |
Metoclopramide | 046 [2] 46, 51 💬 💬 |
353 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Pimozide Pimozide 💬 |
Pimozide | 002 [1] 2 💬 💬 |
354 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Piribedil Piribedil 💬 |
Piribedil | 006 [1] 6 💬 💬 |
355 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Pramipexole Pramipexole 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 💬 |
356 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Pridopidine Pridopidine 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 💬 |
357 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Quetiapine Quetiapine 💬 |
Quetiapine | 006 [2] 6 , 13 💬 💬 |
358 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Risperidone Risperidone 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 💬 |
359 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Ropinirole Ropinirole 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 💬 |
360 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Rotigotine Rotigotine 💬 |
Rotigotine | 006 [1] 6 💬 💬 |
361 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Sulpiride Sulpiride 💬 |
Sulpiride | 006 [2] 6 , 70 💬 💬 |
362 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
363 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Tiapride Tiapride 💬 |
Tiapride | 008 [1] 8 💬 💬 |
364 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
365 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
366 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR1A 💬 |
Aripiprazole Aripiprazole 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 💬 |
367 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR1A 💬 |
Buspirone Buspirone 💬 |
Buspirone | 006 [2] 6 , 51 💬 💬 |
368 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR1A 💬 |
Cariprazine Cariprazine 💬 |
Cariprazine | 021 [1] 21 💬 💬 |
369 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR1A 💬 |
Pardoprunox Pardoprunox 💬 |
Pardoprunox | 006 [1] 6 💬 💬 |
370 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR6 💬 |
Olanzapine Olanzapine 💬 |
Olanzapine | 002 [2] 2 , 8 💬 💬 |
371 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
372 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
373 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
374 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Macitentan Macitentan 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 💬 |
375 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Sitaxentan Sitaxentan 💬 |
Sitaxentan | 086 [1] 86 💬 💬 |
376 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
377 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Zibotentan Zibotentan 💬 |
Zibotentan | 051 [1] 51 💬 💬 |
378 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Arbaclofen Arbaclofen 💬 |
Arbaclofen | 013 [2] 13, 206 💬 💬 |
379 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Arbaclofen placarbil Arbaclofen placarbil 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 💬 |
380 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
381 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Valiloxybate Valiloxybate 💬 |
Valiloxybate | 006 [1] 6 💬 💬 |
382 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GHSR [1] GHSR 💬 |
Macimorelin Macimorelin 💬 |
Macimorelin | 078 [1] 78 💬 💬 |
383 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GIPR [2] GIPR, GLP1R 💬 |
Tirzepatide Tirzepatide 💬 |
Tirzepatide | 233 [1] 233 💬 💬 |
384 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GLP1R [1] GLP1R 💬 |
Dulaglutide Dulaglutide 💬 |
Dulaglutide | 013 [2] 13, 299 💬 💬 |
385 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GLP1R [1] GLP1R 💬 |
Exenatide Exenatide 💬 |
Exenatide | 006 [6] 6 , 17, 72, 78, 193, 233 💬 💬 |
386 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GLP1R [1] GLP1R 💬 |
Liraglutide Liraglutide 💬 |
Liraglutide | 006 [3] 6 , 75, 193 💬 💬 |
387 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GLP1R [1] GLP1R 💬 |
Lixisenatide Lixisenatide 💬 |
Lixisenatide | 006 [1] 6 💬 💬 |
388 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GLP1R [1] GLP1R 💬 |
Semaglutide Semaglutide 💬 |
Semaglutide | 006 [1] 6 💬 💬 |
389 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Perampanel Perampanel 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 💬 |
390 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Talampanel Talampanel 💬 |
Talampanel | 002 [2] 2 , 6 💬 💬 |
391 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
392 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
393 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
394 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
395 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
396 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
397 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
398 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
399 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR1A [1] HTR1A 💬 |
Vortioxetine Vortioxetine 💬 |
Vortioxetine | 006 [1] 6 💬 💬 |
400 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR1B [2] HTR1B, HTR1D 💬 |
Zolmitriptan Zolmitriptan 💬 |
Zolmitriptan | 006 [1] 6 💬 💬 |
401 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR1D [1] HTR1D 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
402 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR4 [1] HTR4 💬 |
Cisapride Cisapride 💬 |
Cisapride | 013 [1] 13 💬 💬 |
403 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR4 [1] HTR4 💬 |
Cisapride Cisapride 💬 |
Cisapride | 013 [1] 13 💬 💬 |
404 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR4 [1] HTR4 💬 |
Mosapride Mosapride 💬 |
Mosapride | 096 [1] 96 💬 💬 |
405 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR4 [1] HTR4 💬 |
Prucalopride Prucalopride 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 💬 |
406 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR4 [1] HTR4 💬 |
Velusetrag Velusetrag 💬 |
Velusetrag | 099 [1] 99 💬 💬 |
407 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
408 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
409 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
410 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
411 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
412 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R [1] MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
413 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R [1] MC2R 💬 |
Cosyntropin Cosyntropin 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 💬 |
414 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
415 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
NPR1 [1] NPR1 💬 |
Erythrityl tetranitrate Erythrityl tetranitrate 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 💬 |
416 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
NPR1 [1] NPR1 💬 |
Nesiritide Nesiritide 💬 |
Nesiritide | 046 [2] 46, 58 💬 💬 |
417 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
OXTR [1] OXTR 💬 |
Atosiban Atosiban 💬 |
Atosiban | 118 [1] 118 💬 💬 |
418 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
OXTR [1] OXTR 💬 |
Oxytocin Oxytocin 💬 |
Oxytocin | 006 [7] 6 , 72, 127, 168, 193, 206, 226 💬 💬 |
419 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
420 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
421 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
422 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
423 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
424 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
425 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [1] PDE4A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
426 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
427 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
428 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
429 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
430 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
431 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
432 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
433 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
434 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬 |
Elafibranor Elafibranor 💬 |
Elafibranor | 093 [2] 93, 94 💬 💬 |
435 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬 💬 |
436 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬 |
Pemafibrate Pemafibrate 💬 |
Pemafibrate | 093 [1] 93 💬 💬 |
437 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PTGER2 [2] PTGER2, PTGER3 💬 |
Misoprostol Misoprostol 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 💬 |
438 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
439 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
440 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
441 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR1 [3] SSTR1, SSTR2, SSTR5 💬 |
Pasireotide Pasireotide 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 💬 |
442 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR1 [3] SSTR1, SSTR2, SSTR5 💬 |
Somatostatin Somatostatin 💬 |
Somatostatin | 067 [2] 67, 78 💬 💬 |
443 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 [1] SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 💬 |
444 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
AMY2A [3] AMY2A, AMY2B, MGAM 💬 |
Acarbose Acarbose 💬 |
Acarbose | 298 [1] 298 💬 💬 |
445 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
446 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
447 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
448 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
449 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
450 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
451 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
452 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
453 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
454 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
455 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
456 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
457 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
458 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
459 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
460 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
461 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
462 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
Aspartame Aspartame 💬 |
Aspartame | 006 [4] 6 , 13, 67, 86 💬 💬 |
463 | Carbon metabolism 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬 |
Carglumic acid Carglumic acid 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 💬 |
464 | Carbon metabolism 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
HAO1 [1] HAO1 💬 |
Lumasiran Lumasiran 💬 |
Lumasiran | 234 [1] 234 💬 💬 |
465 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
466 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
467 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
468 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
469 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
470 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
471 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
472 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
473 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
474 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
475 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
476 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
477 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
478 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
Mirogabalin Mirogabalin 💬 |
Mirogabalin | 070 [1] 70 💬 💬 |
479 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Gabapentin Gabapentin 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 💬 |
480 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Pregabalin Pregabalin 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 💬 |
481 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
MYH7 [1] MYH7 💬 |
Mavacamten Mavacamten 💬 |
Mavacamten | 058 [1] 58 💬 💬 |
482 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD22 [1] CD22 💬 |
Epratuzumab Epratuzumab 💬 |
Epratuzumab | 049 [1] 49 💬 💬 |
483 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬 |
Atezolizumab Atezolizumab 💬 |
Atezolizumab | 085 [1] 85 💬 💬 |
484 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬 |
Durvalumab Durvalumab 💬 |
Durvalumab | 085 [1] 85 💬 💬 |
485 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD4 [1] CD4 💬 |
Zanolimumab Zanolimumab 💬 |
Zanolimumab | 046 [1] 46 💬 💬 |
486 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD40 [1] CD40 💬 |
Bleselumab Bleselumab 💬 |
Bleselumab | 222 [1] 222 💬 💬 |
487 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD40 [1] CD40 💬 |
Iscalimab Iscalimab 💬 |
Iscalimab | 049 [2] 49, 53 💬 💬 |
488 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD40 [1] CD40 💬 |
Ravagalimab Ravagalimab 💬 |
Ravagalimab | 053 [2] 53, 97 💬 💬 |
489 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD40LG [1] CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 [1] 63 💬 💬 |
490 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD58 [1] CD58 💬 |
Alefacept Alefacept 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 💬 |
491 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD6 [1] CD6 💬 |
Itolizumab Itolizumab 💬 |
Itolizumab | 049 [1] 49 💬 💬 |
492 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 [2] CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
493 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 [2] CD80, CD86 💬 |
Belatacept Belatacept 💬 |
Belatacept | 046 [1] 46 💬 💬 |
494 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CTLA4 [1] CTLA4 💬 |
Ipilimumab Ipilimumab 💬 |
Ipilimumab | 159 [1] 159 💬 💬 |
495 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CTLA4 [1] CTLA4 💬 |
Tremelimumab Tremelimumab 💬 |
Tremelimumab | 096 [1] 96 💬 💬 |
496 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGA4 [1] ITGA4 💬 |
Firategrast Firategrast 💬 |
Firategrast | 013 [1] 13 💬 💬 |
497 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGA4 [1] ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 💬 |
498 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Abrilumab Abrilumab 💬 |
Abrilumab | 096 [2] 96, 97 💬 💬 |
499 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Vedolizumab Vedolizumab 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 💬 |
500 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
501 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGB7 [1] ITGB7 💬 |
Etrolizumab Etrolizumab 💬 |
Etrolizumab | 096 [2] 96, 97 💬 💬 |
502 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 [1] PDCD1 💬 |
Nivolumab Nivolumab 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 💬 |
503 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 [1] PDCD1 💬 |
Pembrolizumab Pembrolizumab 💬 |
Pembrolizumab | 025 [2] 25, 285 💬 💬 |
504 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
505 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
506 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
507 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
508 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
509 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
510 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
511 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
HDAC1 [3] HDAC1, HDAC2, HDAC8 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 [2] 75, 96 💬 💬 |
512 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
PLK1 [1] PLK1 💬 |
Rigosertib Rigosertib 💬 |
Rigosertib | 036 [1] 36 💬 💬 |
513 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
514 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
515 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
516 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
517 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
518 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
519 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
520 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
521 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
522 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
523 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
524 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
525 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
526 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
527 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [1] IL1A 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
528 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [2] IL1A, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
529 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
530 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
531 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
532 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
533 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
534 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
535 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
536 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
537 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
538 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
539 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
540 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
541 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
542 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
543 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
544 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
545 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
546 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
547 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
548 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
549 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
550 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
551 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
552 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
553 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
554 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
555 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
556 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
557 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
558 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
559 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
560 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
561 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
562 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
563 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
564 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
565 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [2] FLT3, KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
566 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
567 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
568 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
569 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
570 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
571 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
572 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
573 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
574 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
575 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
576 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
577 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
578 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
579 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
580 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
581 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
582 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
583 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
584 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
585 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [2] ADORA1, ADORA3 💬 |
Adenosine Adenosine 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 💬 |
586 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [2] ADORA1, ADORA3 💬 |
Adenosine phosphate Adenosine phosphate 💬 |
Adenosine phosphate | 046 [1] 46 💬 💬 |
587 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
588 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
589 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
590 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
591 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
592 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA3 [1] ADORA3 💬 |
Piclidenoson Piclidenoson 💬 |
Piclidenoson | 046 [1] 46 💬 💬 |
593 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [1] ADRA1A 💬 |
Alfuzosin Alfuzosin 💬 |
Alfuzosin | 013 [1] 13 💬 💬 |
594 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [1] ADRA1A 💬 |
Silodosin Silodosin 💬 |
Silodosin | 006 [2] 6 , 13 💬 💬 |
595 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
596 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Midodrine Midodrine 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 💬 |
597 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Olanzapine Olanzapine 💬 |
Olanzapine | 002 [2] 2 , 8 💬 💬 |
598 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Phenylephrine Phenylephrine 💬 |
Phenylephrine | 022 [1] 22 💬 💬 |
599 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Tamsulosin Tamsulosin 💬 |
Tamsulosin | 013 [1] 13 💬 💬 |
600 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Terazosin Terazosin 💬 |
Terazosin | 006 [1] 6 💬 💬 |
601 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
Methylergometrine Methylergometrine 💬 |
Methylergometrine | 280 [1] 280 💬 💬 |
602 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Dipivefrin Dipivefrin 💬 |
Dipivefrin | 006 [1] 6 💬 💬 |
603 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Droxidopa Droxidopa 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 💬 |
604 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Ephedrine Ephedrine 💬 |
Ephedrine | 011 [1] 11 💬 💬 |
605 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Epinephrine Epinephrine 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 💬 |
606 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Noradrenaline Noradrenaline 💬 |
Norepinephrine | 022 [2] 22, 296 💬 💬 |
607 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
Pseudoephedrine Pseudoephedrine 💬 |
Pseudoephedrine | 017 [1] 17 💬 💬 |
608 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
609 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
610 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [1] ADRA2A 💬 |
Guanfacine Guanfacine 💬 |
Guanfacine | 193 [1] 193 💬 💬 |
611 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [1] ADRA2A 💬 |
Pimozide Pimozide 💬 |
Pimozide | 002 [1] 2 💬 💬 |
612 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Apraclonidine Apraclonidine 💬 |
Apraclonidine | 011 [1] 11 💬 💬 |
613 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Brimonidine Brimonidine 💬 |
Brimonidine | 013 [2] 13, 90 💬 💬 |
614 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
615 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Clonidine Clonidine 💬 |
Clonidine | 006 [4] 6 , 65, 70, 78 💬 💬 |
616 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Clozapine Clozapine 💬 |
Clozapine | 006 [1] 6 💬 💬 |
617 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Dexmedetomidine Dexmedetomidine 💬 |
Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 💬 |
618 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Guanabenz Guanabenz 💬 |
Guanabenz | 002 [2] 2 , 13 💬 💬 |
619 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Rilmenidine Rilmenidine 💬 |
Rilmenidine | 008 [1] 8 💬 💬 |
620 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Tizanidine Tizanidine 💬 |
Tizanidine | 013 [1] 13 💬 💬 |
621 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
Yohimbine Yohimbine 💬 |
Yohimbine | 006 [1] 6 💬 💬 |
622 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Atenolol Atenolol 💬 |
Atenolol | 167 [1] 167 💬 💬 |
623 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Bisoprolol Bisoprolol 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 💬 |
624 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Celiprolol Celiprolol 💬 |
Celiprolol | 168 [1] 168 💬 💬 |
625 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
626 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Esmolol Esmolol 💬 |
Esmolol | 058 [1] 58 💬 💬 |
627 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
628 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Nebivolol Nebivolol 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 💬 |
629 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Nadolol Nadolol 💬 |
Nadolol | 006 [1] 6 💬 💬 |
630 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
631 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
632 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Propranolol Propranolol 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 💬 |
633 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Clenbuterol Clenbuterol 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 💬 |
634 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Formoterol Formoterol 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 💬 |
635 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Isoxsuprine Isoxsuprine 💬 |
Isoxsuprine | 013 [1] 13 💬 💬 |
636 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Levosalbutamol Levosalbutamol 💬 |
Levosalbutamol | 049 [1] 49 💬 💬 |
637 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
638 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Salmeterol Salmeterol 💬 |
Salmeterol | 299 [1] 299 💬 💬 |
639 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Terbutaline Terbutaline 💬 |
Terbutaline | 118 [1] 118 💬 💬 |
640 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Tulobuterol Tulobuterol 💬 |
Tulobuterol | 006 [1] 6 💬 💬 |
641 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB3 [1] ADRB3 💬 |
Mirabegron Mirabegron 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 💬 |
642 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
643 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
644 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
645 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
646 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
647 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
648 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
649 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
650 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [2] AGTR1, EDNRA 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
651 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
652 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
653 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
654 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
655 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
656 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
657 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
658 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
659 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
660 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
661 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
662 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
663 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
664 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
665 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬 |
Sitaxentan Sitaxentan 💬 |
Sitaxentan | 086 [1] 86 💬 💬 |
666 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬 |
Zibotentan Zibotentan 💬 |
Zibotentan | 051 [1] 51 💬 💬 |
667 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
668 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
669 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Macitentan Macitentan 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 💬 |
670 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
671 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
672 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
673 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
674 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
675 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
676 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
677 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
678 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
679 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
680 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MYH7 [1] MYH7 💬 |
Mavacamten Mavacamten 💬 |
Mavacamten | 058 [1] 58 💬 💬 |
681 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
NPR1 [1] NPR1 💬 |
Nesiritide Nesiritide 💬 |
Nesiritide | 046 [2] 46, 58 💬 💬 |
682 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
NPR1 [2] NPR1, NPR2 💬 |
Erythrityl tetranitrate Erythrityl tetranitrate 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 💬 |
683 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
NPR2 [1] NPR2 💬 |
Vosoritide Vosoritide 💬 |
Vosoritide | 276 [1] 276 💬 💬 |
684 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Loperamide Loperamide 💬 |
Loperamide | 013 [2] 13, 97 💬 💬 |
685 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Nalbuphine Nalbuphine 💬 |
Nalbuphine | 085 [1] 85 💬 💬 |
686 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Nalmefene Nalmefene 💬 |
Nalmefene | 006 [1] 6 💬 💬 |
687 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Naloxone Naloxone 💬 |
Naloxone | 006 [2] 6 , 226 💬 💬 |
688 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
689 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Oxycodone Oxycodone 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 💬 |
690 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
691 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
692 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
693 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
694 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
695 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
696 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
697 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
698 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
699 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Udenafil Udenafil 💬 |
Udenafil | 086 [2] 86, 210 💬 💬 |
700 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Vardenafil Vardenafil 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 💬 |
701 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
702 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
703 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
704 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
705 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
706 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PRKCE [1] PRKCE 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
707 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
708 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
709 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
710 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
711 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Captopril Captopril 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 💬 |
712 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Cilazapril Cilazapril 💬 |
Cilazapril | 066 [1] 66 💬 💬 |
713 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Cilazapril Cilazapril 💬 |
Cilazapril | 066 [1] 66 💬 💬 |
714 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Enalapril Enalapril 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 💬 |
715 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Imidapril Imidapril 💬 |
Imidapril | 067 [1] 67 💬 💬 |
716 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Lisinopril Lisinopril 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 💬 |
717 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Lisinopril Lisinopril 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 💬 |
718 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Moexipril Moexipril 💬 |
Moexipril | 093 [1] 93 💬 💬 |
719 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Perindopril Perindopril 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 💬 |
720 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Quinapril Quinapril 💬 |
Quinapril | 019 [1] 19 💬 💬 |
721 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Ramipril Ramipril 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 💬 |
722 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
C3 [1] C3 💬 |
Pegcetacoplan Pegcetacoplan 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 💬 |
723 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
724 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Otelixizumab Otelixizumab 💬 |
Otelixizumab | 046 [1] 46 💬 💬 |
725 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Visilizumab Visilizumab 💬 |
Visilizumab | 096 [2] 96, 97 💬 💬 |
726 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CD3E [1] CD3E 💬 |
Mosunetuzumab Mosunetuzumab 💬 |
Mosunetuzumab | 049 [1] 49 💬 💬 |
727 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
728 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
729 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
Interferon gamma-1b Interferon gamma-1b 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 💬 |
730 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
731 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
732 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
733 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
734 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
735 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
736 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
737 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
738 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
739 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
740 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
741 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
742 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
743 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
744 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
745 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
746 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TLR9 [1] TLR9 💬 |
Cobitolimod Cobitolimod 💬 |
Cobitolimod | 097 [1] 97 💬 💬 |
747 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
748 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
749 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
750 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
751 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
752 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
753 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
754 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
755 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
756 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
757 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
758 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
759 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
760 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
761 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
762 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
763 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
764 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
765 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
766 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
767 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
768 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
769 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
770 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
771 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
772 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
773 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
774 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
775 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
776 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
777 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
778 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
779 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
780 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
781 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
782 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
783 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
784 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
785 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
786 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
787 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
788 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
789 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
790 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
791 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
792 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
793 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
794 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
795 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
HMOX1 [1] HMOX1 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
796 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
KEAP1 [1] KEAP1 💬 |
Dimethyl fumarate Dimethyl fumarate 💬 |
Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬 💬 |
797 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
798 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
799 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
800 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
801 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
802 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
803 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
804 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
805 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
806 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NFE2L2 [1] NFE2L2 💬 |
Omaveloxolone Omaveloxolone 💬 |
Omaveloxolone | 018 [1] 18 💬 💬 |
807 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
808 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NQO1 [1] NQO1 💬 |
Warfarin Warfarin 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬 |
809 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
810 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
811 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
812 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
PRKCD [1] PRKCD 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
813 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
814 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |
815 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
816 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
817 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
818 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
819 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Atenolol Atenolol 💬 |
Atenolol | 167 [1] 167 💬 💬 |
820 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Bisoprolol Bisoprolol 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 💬 |
821 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Celiprolol Celiprolol 💬 |
Celiprolol | 168 [1] 168 💬 💬 |
822 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
823 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Esmolol Esmolol 💬 |
Esmolol | 058 [1] 58 💬 💬 |
824 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
825 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Nebivolol Nebivolol 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 💬 |
826 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
827 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Nadolol Nadolol 💬 |
Nadolol | 006 [1] 6 💬 💬 |
828 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
829 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
830 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Dipivefrin Dipivefrin 💬 |
Dipivefrin | 006 [1] 6 💬 💬 |
831 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Droxidopa Droxidopa 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 💬 |
832 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Ephedrine Ephedrine 💬 |
Ephedrine | 011 [1] 11 💬 💬 |
833 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Epinephrine Epinephrine 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 💬 |
834 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Noradrenaline Noradrenaline 💬 |
Norepinephrine | 022 [2] 22, 296 💬 💬 |
835 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Propranolol Propranolol 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 💬 |
836 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
Pseudoephedrine Pseudoephedrine 💬 |
Pseudoephedrine | 017 [1] 17 💬 💬 |
837 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Clenbuterol Clenbuterol 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 💬 |
838 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Formoterol Formoterol 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 💬 |
839 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Isoxsuprine Isoxsuprine 💬 |
Isoxsuprine | 013 [1] 13 💬 💬 |
840 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Levosalbutamol Levosalbutamol 💬 |
Levosalbutamol | 049 [1] 49 💬 💬 |
841 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
842 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Salmeterol Salmeterol 💬 |
Salmeterol | 299 [1] 299 💬 💬 |
843 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Terbutaline Terbutaline 💬 |
Terbutaline | 118 [1] 118 💬 💬 |
844 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Tulobuterol Tulobuterol 💬 |
Tulobuterol | 006 [1] 6 💬 💬 |
845 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB3 [1] ADRB3 💬 |
Mirabegron Mirabegron 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 💬 |
846 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Calusterone Calusterone 💬 |
Calusterone | 002 [1] 2 💬 💬 |
847 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Flutamide Flutamide 💬 |
Flutamide | 081 [1] 81 💬 💬 |
848 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Nandrolone Nandrolone 💬 |
Nandrolone | 060 [2] 60, 85 💬 💬 |
849 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Nandrolone decanoate Nandrolone decanoate 💬 |
Nandrolone decanoate | 060 [2] 60, 85 💬 💬 |
850 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
851 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Stanozolol Stanozolol 💬 |
Stanozolol | 060 [1] 60 💬 💬 |
852 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
853 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone decanoate Testosterone decanoate 💬 |
Testosterone decanoate | 113 [1] 113 💬 💬 |
854 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone enanthate Testosterone enanthate 💬 |
Testosterone enanthate | 113 [1] 113 💬 💬 |
855 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone phenylpropionate Testosterone phenylpropionate 💬 |
Testosterone phenylpropionate | 113 [1] 113 💬 💬 |
856 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone propionate Testosterone propionate 💬 |
Testosterone propionate | 113 [1] 113 💬 💬 |
857 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone undecanoate Testosterone undecanoate 💬 |
Testosterone undecanoate | 013 [2] 13, 60 💬 💬 |
858 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [3] AR, ESR1, ESR2 💬 |
Prasterone Prasterone 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 💬 |
859 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [3] AR, ESR1, PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
860 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
861 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
862 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
863 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
864 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
865 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
866 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
867 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
868 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
869 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
870 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
871 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
872 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 💬 |
873 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CHRNA4 [2] CHRNA4, CHRNB2 💬 |
Varenicline Varenicline 💬 |
Varenicline | 006 [3] 6 , 18, 53 💬 💬 |
874 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
875 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
876 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
877 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
878 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
879 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
880 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
881 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [1] ESR1 💬 |
Ethinyl estradiol Ethinyl estradiol 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 💬 |
882 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Clomifene Clomifene 💬 |
Clomifene | 074 [1] 74 💬 💬 |
883 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
884 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
885 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol Estradiol 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 💬 |
886 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol valerate Estradiol valerate 💬 |
Estradiol valerate | 065 [1] 65 💬 💬 |
887 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol Estriol 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
888 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol tripropionate Estriol tripropionate 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
889 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Fulvestrant Fulvestrant 💬 |
Fulvestrant | 049 [2] 49, 86 💬 💬 |
890 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Mestranol Mestranol 💬 |
Mestranol | 046 [2] 46, 49 💬 💬 |
891 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Raloxifene Raloxifene 💬 |
Raloxifene | 046 [1] 46 💬 💬 |
892 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Tamoxifen Tamoxifen 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 💬 |
893 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, PGR 💬 |
Desogestrel Desogestrel 💬 |
Desogestrel | 230 [1] 230 💬 💬 |
894 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 [1] JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
895 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 [1] JAK2 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
896 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 [1] JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
897 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 [1] JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
898 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
899 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
900 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
901 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
902 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
903 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
904 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
905 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
906 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
907 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Dydrogesterone Dydrogesterone 💬 |
Dydrogesterone | 013 [1] 13 💬 💬 |
908 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Levonorgestrel Levonorgestrel 💬 |
Levonorgestrel | 013 [1] 13 💬 💬 |
909 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬 |
Medroxyprogesterone acetate | 013 [8] 13, 35, 46, 49, 50, 51, 60, 107 💬 💬 |
910 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Megestrol acetate Megestrol acetate 💬 |
Megestrol acetate | 076 [1] 76 💬 💬 |
911 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Mifepristone Mifepristone 💬 |
Mifepristone | 075 [1] 75 💬 💬 |
912 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Nomegestrol Nomegestrol 💬 |
Nomegestrol | 013 [1] 13 💬 💬 |
913 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Nomegestrol acetate Nomegestrol acetate 💬 |
Nomegestrol acetate | 013 [1] 13 💬 💬 |
914 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Norethindrone Norethindrone 💬 |
Norethisterone | 013 [4] 13, 46, 49, 299 💬 💬 |
915 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Norgestimate Norgestimate 💬 |
Norgestimate | 299 [1] 299 💬 💬 |
916 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Progesterone Progesterone 💬 |
Progesterone | 076 [2] 76, 299 💬 💬 |
917 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
918 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
919 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
920 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
921 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
922 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬 |
Elafibranor Elafibranor 💬 |
Elafibranor | 093 [2] 93, 94 💬 💬 |
923 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬 💬 |
924 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬 |
Pemafibrate Pemafibrate 💬 |
Pemafibrate | 093 [1] 93 💬 💬 |
925 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
926 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
927 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
928 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
929 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Alitretinoin Alitretinoin 💬 |
Alitretinoin | 049 [1] 49 💬 💬 |
930 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Bexarotene Bexarotene 💬 |
Bexarotene | 013 [2] 13, 75 💬 💬 |
931 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
932 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
933 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
934 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
935 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
TNFSF11 [1] TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
936 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Alfacalcidol Alfacalcidol 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 💬 |
937 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Calcifediol Calcifediol 💬 |
Calcifediol | 113 [2] 113, 299 💬 💬 |
938 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Calcipotriene Calcipotriene 💬 |
Calcipotriol | 036 [2] 36, 51 💬 💬 |
939 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
940 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
941 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Dihydrotachysterol Dihydrotachysterol 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 💬 |
942 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Eldecalcitol Eldecalcitol 💬 |
Eldecalcitol | 046 [1] 46 💬 💬 |
943 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 💬 |
944 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Paricalcitol Paricalcitol 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 💬 |
945 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
946 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
947 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
948 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
949 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
950 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 [1] CCL2 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
951 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCR2 [2] CCR2, CCR5 💬 |
Cenicriviroc Cenicriviroc 💬 |
Cenicriviroc | 094 [1] 94 💬 💬 |
952 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCR4 [1] CCR4 💬 |
Mogamulizumab Mogamulizumab 💬 |
Mogamulizumab | 026 [1] 26 💬 💬 |
953 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCR5 [1] CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 [2] 46, 84 💬 💬 |
954 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CXCR1 [2] CXCR1, CXCR2 💬 |
Reparixin Reparixin 💬 |
Reparixin | 298 [2] 298, 299 💬 💬 |
955 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CXCR4 [1] CXCR4 💬 |
Plerixafor Plerixafor 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 💬 |
956 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 [1] JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
957 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 [1] JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
958 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 [2] JAK2, JAK3 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
959 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 [2] JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
960 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
961 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
962 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
963 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
964 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
965 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
966 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
967 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
968 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
969 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
970 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
PRKCD [1] PRKCD 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
971 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
972 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
973 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
974 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
975 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
976 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
977 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
978 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
ANGPTL3 [1] ANGPTL3 💬 |
Evinacumab Evinacumab 💬 |
Evinacumab | 079 [1] 79 💬 💬 |
979 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
APOC3 [1] APOC3 💬 |
Volanesorsen Volanesorsen 💬 |
Volanesorsen | 265 [1] 265 💬 💬 |
980 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
CETP [1] CETP 💬 |
Anacetrapib Anacetrapib 💬 |
Anacetrapib | 079 [1] 79 💬 💬 |
981 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
LIPA [1] LIPA 💬 |
Sebelipase alfa Sebelipase alfa 💬 |
Sebelipase alfa | 019 [1] 19 💬 💬 |
982 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
PCSK9 [1] PCSK9 💬 |
Alirocumab Alirocumab 💬 |
Alirocumab | 079 [1] 79 💬 💬 |
983 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
PCSK9 [1] PCSK9 💬 |
Evolocumab Evolocumab 💬 |
Evolocumab | 079 [2] 79, 222 💬 💬 |
984 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
PCSK9 [1] PCSK9 💬 |
Inclisiran Inclisiran 💬 |
Inclisiran | 079 [1] 79 💬 💬 |
985 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
SORT1 [1] SORT1 💬 |
Latozinemab Latozinemab 💬 |
Latozinemab | 002 [2] 2 , 127 💬 💬 |
986 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
987 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
988 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
989 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
990 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
991 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
992 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
993 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
994 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
995 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
996 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
997 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
998 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
999 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
1000 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
1001 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
1002 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
1003 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
1004 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
1005 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1006 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1007 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1008 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1009 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1010 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1011 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
1012 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬 |
Donepezil Donepezil 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 💬 |
1013 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬 |
Galantamine Galantamine 💬 |
Galantamine | 006 [2] 6 , 127 💬 💬 |
1014 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
1015 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬 |
Rivastigmine Rivastigmine 💬 |
Rivastigmine | 005 [3] 5 , 6 , 13 💬 💬 |
1016 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬 |
Tacrine Tacrine 💬 |
Tacrine | 046 [2] 46, 271 💬 💬 |
1017 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
1018 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
1019 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
1020 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
1021 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
1022 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
1023 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
1024 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
1025 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
1026 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1027 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
1028 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
1029 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
1030 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
1031 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
1032 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
1033 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
1034 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
1035 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
1036 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
1037 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM2 [2] CHRM2, CHRM3 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
1038 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM3 [1] CHRM3 💬 |
Cevimeline Cevimeline 💬 |
Cevimeline | 053 [1] 53 💬 💬 |
1039 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM3 [1] CHRM3 💬 |
Darifenacin Darifenacin 💬 |
Darifenacin | 006 [2] 6 , 13 💬 💬 |
1040 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM3 [1] CHRM3 💬 |
Solifenacin Solifenacin 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 💬 |
1041 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM3 [1] CHRM3 💬 |
Tolterodine Tolterodine 💬 |
Tolterodine | 017 [2] 17, 53 💬 💬 |
1042 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 💬 |
1043 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRNA4 [2] CHRNA4, CHRNB2 💬 |
Varenicline Varenicline 💬 |
Varenicline | 006 [3] 6 , 18, 53 💬 💬 |
1044 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1045 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1046 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 [1] JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
1047 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 [1] JAK2 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
1048 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 [1] JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
1049 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 [1] JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
1050 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
KCNJ12 [3] KCNJ12, KCNJ3, KCNQ1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
1051 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
KCNQ1 [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 |
Ezogabine Ezogabine 💬 |
Ezogabine | 002 [2] 2 , 144 💬 💬 |
1052 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1053 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1054 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1055 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1056 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1057 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1058 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1059 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1060 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
1061 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
1062 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1063 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1064 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
1065 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
1066 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
1067 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1068 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1069 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
1070 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 [2] 75, 96 💬 💬 |
1071 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1072 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1073 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1074 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1075 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1076 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1077 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1078 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1079 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1080 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
1081 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
1082 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
1083 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
1084 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
1085 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
1086 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
1087 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
1088 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
1089 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
1090 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
1091 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
1092 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1093 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Flunarizine Flunarizine 💬 |
Flunarizine | 149 [1] 149 💬 💬 |
1094 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
1095 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Zonisamide Zonisamide 💬 |
Zonisamide | 006 [1] 6 💬 💬 |
1096 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Perampanel Perampanel 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 💬 |
1097 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Talampanel Talampanel 💬 |
Talampanel | 002 [2] 2 , 6 💬 💬 |
1098 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
1099 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
1100 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
1101 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
1102 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
1103 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
1104 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
1105 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
1106 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
1107 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
1108 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
1109 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Agomelatine Agomelatine 💬 |
Agomelatine | 006 [1] 6 💬 💬 |
1110 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Melatonin Melatonin 💬 |
Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬 |
1111 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Ramelteon Ramelteon 💬 |
Ramelteon | 006 [3] 6 , 8 , 46 💬 💬 |
1112 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Tasimelteon Tasimelteon 💬 |
Tasimelteon | 202 [1] 202 💬 💬 |
1113 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
1114 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
1115 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DDC [1] DDC 💬 |
Benserazide Benserazide 💬 |
Benserazide | 006 [1] 6 💬 💬 |
1116 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
1117 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [1] DRD1 💬 |
Tavapadon Tavapadon 💬 |
Tavapadon | 006 [1] 6 💬 💬 |
1118 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Apomorphine Apomorphine 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 💬 |
1119 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Dexpramipexole Dexpramipexole 💬 |
Dexpramipexole | 002 [1] 2 💬 💬 |
1120 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Dopamine Dopamine 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 💬 |
1121 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Flupentixol Flupentixol 💬 |
Flupentixol | 097 [1] 97 💬 💬 |
1122 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Foslevodopa Foslevodopa 💬 |
Foslevodopa | 006 [1] 6 💬 💬 |
1123 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
1124 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Pergolide Pergolide 💬 |
Pergolide | 006 [1] 6 💬 💬 |
1125 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Aripiprazole Aripiprazole 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 💬 |
1126 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
1127 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Buspirone Buspirone 💬 |
Buspirone | 006 [2] 6 , 51 💬 💬 |
1128 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
1129 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Cariprazine Cariprazine 💬 |
Cariprazine | 021 [1] 21 💬 💬 |
1130 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
1131 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Domperidone Domperidone 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
1132 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Domperidone maleate Domperidone maleate 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
1133 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Haloperidol Haloperidol 💬 |
Haloperidol | 008 [1] 8 💬 💬 |
1134 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Iloperidone Iloperidone 💬 |
Iloperidone | 006 [1] 6 💬 💬 |
1135 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Lisuride Lisuride 💬 |
Lisuride | 006 [2] 6 , 86 💬 💬 |
1136 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Melperone Melperone 💬 |
Melperone | 006 [1] 6 💬 💬 |
1137 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Metoclopramide Metoclopramide 💬 |
Metoclopramide | 046 [2] 46, 51 💬 💬 |
1138 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Olanzapine Olanzapine 💬 |
Olanzapine | 002 [2] 2 , 8 💬 💬 |
1139 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Pardoprunox Pardoprunox 💬 |
Pardoprunox | 006 [1] 6 💬 💬 |
1140 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Pimozide Pimozide 💬 |
Pimozide | 002 [1] 2 💬 💬 |
1141 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Piribedil Piribedil 💬 |
Piribedil | 006 [1] 6 💬 💬 |
1142 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Pramipexole Pramipexole 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 💬 |
1143 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Pridopidine Pridopidine 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 💬 |
1144 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Quetiapine Quetiapine 💬 |
Quetiapine | 006 [2] 6 , 13 💬 💬 |
1145 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Risperidone Risperidone 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 💬 |
1146 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Ropinirole Ropinirole 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 💬 |
1147 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Rotigotine Rotigotine 💬 |
Rotigotine | 006 [1] 6 💬 💬 |
1148 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Sulpiride Sulpiride 💬 |
Sulpiride | 006 [2] 6 , 70 💬 💬 |
1149 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
1150 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Tiapride Tiapride 💬 |
Tiapride | 008 [1] 8 💬 💬 |
1151 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
1152 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
1153 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬 |
Perampanel Perampanel 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 💬 |
1154 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬 |
Talampanel Talampanel 💬 |
Talampanel | 002 [2] 2 , 6 💬 💬 |
1155 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1156 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
1157 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
1158 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
1159 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
1160 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
1161 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
1162 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
1163 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
1164 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOA [1] MAOA 💬 |
Moclobemide Moclobemide 💬 |
Moclobemide | 006 [1] 6 💬 💬 |
1165 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOA [2] MAOA, MAOB 💬 |
Iproniazid Iproniazid 💬 |
Iproniazid | 006 [1] 6 💬 💬 |
1166 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phenelzine Phenelzine 💬 |
Phenelzine | 006 [1] 6 💬 💬 |
1167 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
1168 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
Rasagiline Rasagiline 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
1169 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
Rasagiline tartrate Rasagiline tartrate 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
1170 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
Safinamide Safinamide 💬 |
Safinamide | 006 [2] 6 , 17 💬 💬 |
1171 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
Selegiline Selegiline 💬 |
Selegiline | 006 [1] 6 💬 💬 |
1172 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1173 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
1174 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬 |
Deutetrabenazine Deutetrabenazine 💬 |
Deutetrabenazine | 008 [1] 8 💬 💬 |
1175 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬 |
Tetrabenazine Tetrabenazine 💬 |
Tetrabenazine | 008 [1] 8 💬 💬 |
1176 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬 |
Valbenazine Valbenazine 💬 |
Valbenazine | 008 [1] 8 💬 💬 |
1177 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 💬 |
1178 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
Bupropion Bupropion 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 💬 |
1179 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
Lisdexamfetamine Lisdexamfetamine 💬 |
Lisdexamfetamine | 013 [1] 13 💬 💬 |
1180 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
1181 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Dexlansoprazole Dexlansoprazole 💬 |
Dexlansoprazole | 098 [1] 98 💬 💬 |
1182 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Esomeprazole Esomeprazole 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 💬 |
1183 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 💬 |
1184 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Omeprazole Omeprazole 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 💬 |
1185 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Pantoprazole Pantoprazole 💬 |
Pantoprazole | 013 [2] 13, 65 💬 💬 |
1186 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Rabeprazole Rabeprazole 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 💬 |
1187 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 [2] 63, 98 💬 💬 |
1188 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
CA2 [1] CA2 💬 |
Acetazolamide Acetazolamide 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬 |
1189 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
CA2 [1] CA2 💬 |
Dichlorphenamide Dichlorphenamide 💬 |
Diclofenamide | 114 [1] 114 💬 💬 |
1190 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
CA2 [1] CA2 💬 |
Dorzolamide Dorzolamide 💬 |
Dorzolamide | 090 [1] 90 💬 💬 |
1191 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1192 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
1193 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1194 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1195 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
1196 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
1197 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
1198 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
1199 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
1200 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
1201 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
1202 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
1203 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1204 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1205 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1206 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1207 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1208 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
1209 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
1210 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
1211 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1212 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1213 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1214 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
1215 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C1R [3] C1R, C1S, KLKB1 💬 |
Conestat alfa Conestat alfa 💬 |
Conestat alfa | 061 [1] 61 💬 💬 |
1216 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C1S [1] C1S 💬 |
Sutimlimab Sutimlimab 💬 |
Sutimlimab | 061 [1] 61 💬 💬 |
1217 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C3 [1] C3 💬 |
Pegcetacoplan Pegcetacoplan 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 💬 |
1218 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Crovalimab Crovalimab 💬 |
Crovalimab | 062 [2] 62, 109 💬 💬 |
1219 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Eculizumab Eculizumab 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 💬 |
1220 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Nomacopan Nomacopan 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 💬 |
1221 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Pozelimab Pozelimab 💬 |
Pozelimab | 011 [2] 11, 62 💬 💬 |
1222 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Ravulizumab Ravulizumab 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 💬 |
1223 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Vilobelimab Vilobelimab 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 💬 |
1224 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬 |
Zilucoplan Zilucoplan 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 💬 |
1225 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5AR1 [1] C5AR1 💬 |
Avacopan Avacopan 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 💬 |
1226 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
CFB [1] CFB 💬 |
Iptacopan Iptacopan 💬 |
Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬 💬 |
1227 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
CFD [1] CFD 💬 |
Danicopan Danicopan 💬 |
Danicopan | 062 [1] 62 💬 💬 |
1228 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F10 [1] F10 💬 |
Apixaban Apixaban 💬 |
Apixaban | 222 [1] 222 💬 💬 |
1229 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F10 [1] F10 💬 |
Edoxaban Edoxaban 💬 |
Edoxaban | 046 [2] 46, 88 💬 💬 |
1230 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F10 [1] F10 💬 |
Rivaroxaban Rivaroxaban 💬 |
Rivaroxaban | 046 [4] 46, 49, 91, 210 💬 💬 |
1231 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F10 [2] F10, F9 💬 |
Emicizumab Emicizumab 💬 |
Emicizumab | 288 [1] 288 💬 💬 |
1232 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
1233 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
1234 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
1235 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F8 [1] F8 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |
1236 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
MASP2 [1] MASP2 💬 |
Narsoplimab Narsoplimab 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 💬 |
1237 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
PLG [1] PLG 💬 |
Aminocaproic acid Aminocaproic acid 💬 |
Aminocaproic acid | 070 [1] 70 💬 💬 |
1238 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
PLG [1] PLG 💬 |
Tranexamic acid Tranexamic acid 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 💬 |
1239 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 [1] SERPINC1 💬 |
Adomiparin Adomiparin 💬 |
Enoxaparin | 046 [1] 46 💬 💬 |
1240 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 [1] SERPINC1 💬 |
Adomiparin Adomiparin 💬 |
Heparin | 047 [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 💬 |
1241 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 [1] SERPINC1 💬 |
Adomiparin Adomiparin 💬 |
Parnaparin | 097 [1] 97 💬 💬 |
1242 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 [2] SERPINC1, SERPIND1 💬 |
Sulodexide Sulodexide 💬 |
Sulodexide | 051 [2] 51, 271 💬 💬 |
1243 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
VWF [1] VWF 💬 |
Caplacizumab Caplacizumab 💬 |
Caplacizumab | 064 [1] 64 💬 💬 |
1244 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
1245 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Captopril Captopril 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 💬 |
1246 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Cilazapril Cilazapril 💬 |
Cilazapril | 066 [1] 66 💬 💬 |
1247 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Cilazapril Cilazapril 💬 |
Cilazapril | 066 [1] 66 💬 💬 |
1248 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Enalapril Enalapril 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 💬 |
1249 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Imidapril Imidapril 💬 |
Imidapril | 067 [1] 67 💬 💬 |
1250 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Lisinopril Lisinopril 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 💬 |
1251 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Lisinopril Lisinopril 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 💬 |
1252 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Moexipril Moexipril 💬 |
Moexipril | 093 [1] 93 💬 💬 |
1253 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Perindopril Perindopril 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 💬 |
1254 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Quinapril Quinapril 💬 |
Quinapril | 019 [1] 19 💬 💬 |
1255 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Ramipril Ramipril 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 💬 |
1256 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ADAM17 [1] ADAM17 💬 |
Apratastat Apratastat 💬 |
Apratastat | 046 [1] 46 💬 💬 |
1257 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1258 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1259 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
1260 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
1261 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
1262 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
1263 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
1264 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
1265 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
1266 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C1R [2] C1R, C1S 💬 |
Conestat alfa Conestat alfa 💬 |
Conestat alfa | 061 [1] 61 💬 💬 |
1267 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C1S [1] C1S 💬 |
Sutimlimab Sutimlimab 💬 |
Sutimlimab | 061 [1] 61 💬 💬 |
1268 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C3 [1] C3 💬 |
Pegcetacoplan Pegcetacoplan 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 💬 |
1269 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Crovalimab Crovalimab 💬 |
Crovalimab | 062 [2] 62, 109 💬 💬 |
1270 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Eculizumab Eculizumab 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 💬 |
1271 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Nomacopan Nomacopan 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 💬 |
1272 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Pozelimab Pozelimab 💬 |
Pozelimab | 011 [2] 11, 62 💬 💬 |
1273 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Ravulizumab Ravulizumab 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 💬 |
1274 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Vilobelimab Vilobelimab 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 💬 |
1275 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬 |
Zilucoplan Zilucoplan 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 💬 |
1276 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5AR1 [1] C5AR1 💬 |
Avacopan Avacopan 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 💬 |
1277 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
1278 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CFB [1] CFB 💬 |
Iptacopan Iptacopan 💬 |
Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬 💬 |
1279 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CFD [1] CFD 💬 |
Danicopan Danicopan 💬 |
Danicopan | 062 [1] 62 💬 💬 |
1280 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CSF2 [1] CSF2 💬 |
Otilimab Otilimab 💬 |
Otilimab | 046 [1] 46 💬 💬 |
1281 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
1282 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
1283 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
1284 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
1285 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
1286 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
1287 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
1288 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
1289 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
1290 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
1291 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
1292 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
1293 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 💬 |
1294 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 💬 |
1295 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 [1] 56 💬 💬 |
1296 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 💬 |
1297 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 💬 |
1298 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 [1] 13 💬 💬 |
1299 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 💬 |
1300 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
1301 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
1302 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
1303 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
1304 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
1305 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
1306 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
1307 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
1308 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R [1] IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 💬 |
1309 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R [1] IL6R 💬 |
Satralizumab Satralizumab 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 💬 |
1310 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R [1] IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
1311 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
1312 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
1313 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
1314 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
1315 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
1316 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
1317 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
1318 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [2] JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
1319 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
1320 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
1321 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
MASP2 [1] MASP2 💬 |
Narsoplimab Narsoplimab 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 💬 |
1322 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1323 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1324 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1325 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1326 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
1327 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
1328 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
SYK [1] SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 💬 |
1329 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TLR7 [1] TLR7 💬 |
Imiquimod Imiquimod 💬 |
Imiquimod | 034 [2] 34, 51 💬 💬 |
1330 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
1331 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
1332 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
1333 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
1334 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
1335 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
1336 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
1337 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
1338 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
1339 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TYK2 [1] TYK2 💬 |
Deucravacitinib Deucravacitinib 💬 |
Deucravacitinib | 049 [3] 49, 96, 97 💬 💬 |
1340 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
VWF [1] VWF 💬 |
Caplacizumab Caplacizumab 💬 |
Caplacizumab | 064 [1] 64 💬 💬 |
1341 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1342 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1343 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
1344 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
1345 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
1346 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
1347 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
1348 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
1349 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
1350 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
1351 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
1352 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
1353 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
1354 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
1355 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
1356 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
1357 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
1358 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
1359 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1360 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
1361 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Flunarizine Flunarizine 💬 |
Flunarizine | 149 [1] 149 💬 💬 |
1362 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
1363 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Zonisamide Zonisamide 💬 |
Zonisamide | 006 [1] 6 💬 💬 |
1364 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CYP11A1 [3] CYP11A1, CYP11B1, CYP17A1 💬 |
Levoketoconazole Levoketoconazole 💬 |
Levoketoconazole | 075 [1] 75 💬 💬 |
1365 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CYP11B1 [1] CYP11B1 💬 |
Metyrapone Metyrapone 💬 |
Metyrapone | 075 [1] 75 💬 💬 |
1366 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CYP17A1 [1] CYP17A1 💬 |
Ketoconazole Ketoconazole 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 💬 |
1367 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
KCNA4 [1] KCNA4 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
1368 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
KCNA4 [1] KCNA4 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
1369 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R [1] MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
1370 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R [1] MC2R 💬 |
Cosyntropin Cosyntropin 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 💬 |
1371 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
1372 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
1373 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
1374 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1375 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1376 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1377 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
1378 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
1379 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
1380 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
1381 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
1382 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
1383 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
1384 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
1385 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1386 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1387 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
1388 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
1389 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
1390 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
1391 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
1392 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
1393 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
1394 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
1395 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
1396 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1397 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
1398 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Flunarizine Flunarizine 💬 |
Flunarizine | 149 [1] 149 💬 💬 |
1399 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
1400 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Zonisamide Zonisamide 💬 |
Zonisamide | 006 [1] 6 💬 💬 |
1401 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
1402 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CRHR1 [2] CRHR1, CRHR2 💬 |
Corticorelin Corticorelin 💬 |
Corticorelin | 075 [1] 75 💬 💬 |
1403 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CRHR1 [2] CRHR1, CRHR2 💬 |
Corticorelin ovine triflutate Corticorelin ovine triflutate 💬 |
Corticorelin ovine triflutate | 075 [1] 75 💬 💬 |
1404 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CYP11A1 [3] CYP11A1, CYP11B1, CYP17A1 💬 |
Levoketoconazole Levoketoconazole 💬 |
Levoketoconazole | 075 [1] 75 💬 💬 |
1405 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CYP11B1 [1] CYP11B1 💬 |
Metyrapone Metyrapone 💬 |
Metyrapone | 075 [1] 75 💬 💬 |
1406 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CYP17A1 [1] CYP17A1 💬 |
Ketoconazole Ketoconazole 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 💬 |
1407 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
1408 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
1409 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
1410 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
1411 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
1412 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
1413 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
1414 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
KCNA4 [1] KCNA4 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
1415 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
KCNA4 [1] KCNA4 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
1416 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1417 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1418 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1419 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1420 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1421 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R [1] MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
1422 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R [1] MC2R 💬 |
Cosyntropin Cosyntropin 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 💬 |
1423 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
1424 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
1425 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
1426 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1427 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1428 | Cysteine and methionine metabolism 💬 3 genes, 1 drug (DrugBank) and 3 diseases |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 💬 |
1429 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
ACVR2A [1] ACVR2A 💬 |
Sotatercept Sotatercept 💬 |
Sotatercept | 086 [2] 86, 284 💬 💬 |
1430 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
ACVR2A [2] ACVR2A, ACVR2B 💬 |
Bimagrumab Bimagrumab 💬 |
Bimagrumab | 015 [1] 15 💬 💬 |
1431 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
ACVR2B [1] ACVR2B 💬 |
Luspatercept Luspatercept 💬 |
Luspatercept | 060 [1] 60 💬 💬 |
1432 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
1433 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCR2 [2] CCR2, CCR5 💬 |
Cenicriviroc Cenicriviroc 💬 |
Cenicriviroc | 094 [1] 94 💬 💬 |
1434 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCR4 [1] CCR4 💬 |
Mogamulizumab Mogamulizumab 💬 |
Mogamulizumab | 026 [1] 26 💬 💬 |
1435 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCR5 [1] CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 [2] 46, 84 💬 💬 |
1436 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD4 [1] CD4 💬 |
Zanolimumab Zanolimumab 💬 |
Zanolimumab | 046 [1] 46 💬 💬 |
1437 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD40 [1] CD40 💬 |
Bleselumab Bleselumab 💬 |
Bleselumab | 222 [1] 222 💬 💬 |
1438 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD40 [1] CD40 💬 |
Iscalimab Iscalimab 💬 |
Iscalimab | 049 [2] 49, 53 💬 💬 |
1439 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD40 [1] CD40 💬 |
Ravagalimab Ravagalimab 💬 |
Ravagalimab | 053 [2] 53, 97 💬 💬 |
1440 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD40LG [1] CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 [1] 63 💬 💬 |
1441 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF1R [1] CSF1R 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
1442 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF1R [1] CSF1R 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
1443 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2 [1] CSF2 💬 |
Otilimab Otilimab 💬 |
Otilimab | 046 [1] 46 💬 💬 |
1444 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2RA [1] CSF2RA 💬 |
Mavrilimumab Mavrilimumab 💬 |
Mavrilimumab | 041 [2] 41, 46 💬 💬 |
1445 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2RA [1] CSF2RA 💬 |
Molgramostim Molgramostim 💬 |
Molgramostim | 097 [3] 97, 229, 299 💬 💬 |
1446 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2RA [1] CSF2RA 💬 |
Regramostim Regramostim 💬 |
Regramostim | 229 [1] 229 💬 💬 |
1447 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2RA [1] CSF2RA 💬 |
Sargramostim Sargramostim 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 💬 |
1448 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
1449 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
1450 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
Pegfilgrastim Pegfilgrastim 💬 |
Pegfilgrastim | 060 [1] 60 💬 💬 |
1451 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CXCR1 [2] CXCR1, CXCR2 💬 |
Reparixin Reparixin 💬 |
Reparixin | 298 [2] 298, 299 💬 💬 |
1452 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CXCR4 [1] CXCR4 💬 |
Plerixafor Plerixafor 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 💬 |
1453 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
EPOR [1] EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 [1] 283 💬 💬 |
1454 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR [1] GHR 💬 |
Lonapegsomatropin Lonapegsomatropin 💬 |
Lonapegsomatropin | 078 [1] 78 💬 💬 |
1455 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR [1] GHR 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
1456 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR [1] GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 [2] 78, 265 💬 💬 |
1457 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR [1] GHR 💬 |
Somapacitan Somapacitan 💬 |
Somapacitan | 078 [2] 78, 195 💬 💬 |
1458 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR [1] GHR 💬 |
Somavaratan Somavaratan 💬 |
Somavaratan | 078 [1] 78 💬 💬 |
1459 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
1460 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
1461 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 💬 |
1462 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 💬 |
1463 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 [1] 56 💬 💬 |
1464 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 💬 |
1465 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 💬 |
1466 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 [1] 13 💬 💬 |
1467 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 💬 |
1468 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
1469 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
1470 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
Interferon gamma-1b Interferon gamma-1b 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 💬 |
1471 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL11RA [1] IL11RA 💬 |
Oprelvekin Oprelvekin 💬 |
Oprelvekin | 096 [2] 96, 288 💬 💬 |
1472 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
1473 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬 |
Anrukinzumab Anrukinzumab 💬 |
Anrukinzumab | 097 [1] 97 💬 💬 |
1474 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬 |
Lebrikizumab Lebrikizumab 💬 |
Lebrikizumab | 085 [1] 85 💬 💬 |
1475 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬 |
Tralokinumab Tralokinumab 💬 |
Tralokinumab | 085 [2] 85, 97 💬 💬 |
1476 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
1477 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
1478 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [2] IL17A, IL17F 💬 |
Bimekizumab Bimekizumab 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 💬 |
1479 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [2] IL17A, TNFSF13B 💬 |
Tibulizumab Tibulizumab 💬 |
Tibulizumab | 053 [1] 53 💬 💬 |
1480 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17RA [1] IL17RA 💬 |
Brodalumab Brodalumab 💬 |
Brodalumab | 037 [2] 37, 51 💬 💬 |
1481 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
1482 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
1483 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
1484 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
1485 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
1486 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1RL2 [1] IL1RL2 💬 |
Imsidolimab Imsidolimab 💬 |
Imsidolimab | 037 [1] 37 💬 💬 |
1487 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1RL2 [1] IL1RL2 💬 |
Spesolimab Spesolimab 💬 |
Spesolimab | 037 [3] 37, 96, 97 💬 💬 |
1488 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL20 [1] IL20 💬 |
Fletikumab Fletikumab 💬 |
Fletikumab | 046 [1] 46 💬 💬 |
1489 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL22 [1] IL22 💬 |
Efmarodocokin alfa Efmarodocokin alfa 💬 |
Efmarodocokin alfa | 096 [2] 96, 97 💬 💬 |
1490 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Brazikumab Brazikumab 💬 |
Brazikumab | 096 [2] 96, 97 💬 💬 |
1491 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
1492 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
1493 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
1494 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Tildrakizumab Tildrakizumab 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 💬 |
1495 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
Basiliximab Basiliximab 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 💬 |
1496 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
1497 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
Aldesleukin Aldesleukin 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 💬 |
1498 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL31RA [1] IL31RA 💬 |
Nemolizumab Nemolizumab 💬 |
Nemolizumab | 051 [1] 51 💬 💬 |
1499 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL4 [1] IL4 💬 |
Binetrakin Binetrakin 💬 |
Binetrakin | 046 [1] 46 💬 💬 |
1500 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL4R [1] IL4R 💬 |
Dupilumab Dupilumab 💬 |
Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬 💬 |
1501 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5 [1] IL5 💬 |
Mepolizumab Mepolizumab 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 💬 |
1502 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5 [1] IL5 💬 |
Reslizumab Reslizumab 💬 |
Reslizumab | 044 [2] 44, 98 💬 💬 |
1503 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5RA [1] IL5RA 💬 |
Benralizumab Benralizumab 💬 |
Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬 💬 |
1504 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
1505 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
1506 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
1507 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
1508 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 💬 |
1509 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬 |
Satralizumab Satralizumab 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 💬 |
1510 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
1511 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LEPR [1] LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 [1] 265 💬 💬 |
1512 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA [1] LTA 💬 |
Pateclizumab Pateclizumab 💬 |
Pateclizumab | 046 [1] 46 💬 💬 |
1513 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA [2] LTA, TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
1514 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTB [1] LTB 💬 |
Baminercept Baminercept 💬 |
Baminercept | 013 [4] 13, 46, 53, 97 💬 💬 |
1515 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MPL [1] MPL 💬 |
Avatrombopag Avatrombopag 💬 |
Avatrombopag | 060 [2] 60, 63 💬 💬 |
1516 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MPL [1] MPL 💬 |
Romiplostim Romiplostim 💬 |
Romiplostim | 060 [4] 60, 63, 64, 65 💬 💬 |
1517 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Apitegromab Apitegromab 💬 |
Apitegromab | 003 [1] 3 💬 💬 |
1518 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Domagrozumab Domagrozumab 💬 |
Domagrozumab | 113 [1] 113 💬 💬 |
1519 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Stamulumab Stamulumab 💬 |
Stamulumab | 113 [1] 113 💬 💬 |
1520 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Taldefgrobep alfa Taldefgrobep alfa 💬 |
Talditercept alfa | 003 [1] 3 💬 💬 |
1521 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
NGF [1] NGF 💬 |
Tanezumab Tanezumab 💬 |
Tanezumab | 226 [2] 226, 298 💬 💬 |
1522 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
NGFR [1] NGFR 💬 |
Cenegermin Cenegermin 💬 |
Cenegermin | 053 [2] 53, 90 💬 💬 |
1523 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
PRL [1] PRL 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
1524 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
PRL [1] PRL 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
1525 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
PRL [1] PRL 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
1526 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
1527 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
1528 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
1529 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
1530 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
1531 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
1532 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
1533 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
1534 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
1535 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFRSF13C [1] TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 [7] 35, 46, 49, 53, 61, 63, 95 💬 💬 |
1536 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFRSF17 [1] TNFRSF17 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
1537 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFRSF8 [1] TNFRSF8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
1538 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF11 [1] TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
1539 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF13 [2] TNFSF13, TNFSF13B 💬 |
Atacicept Atacicept 💬 |
Atacicept | 013 [4] 13, 46, 49, 66 💬 💬 |
1540 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF13B [1] TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 [13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
1541 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF13B [1] TNFSF13B 💬 |
Tabalumab Tabalumab 💬 |
Tabalumab | 046 [2] 46, 49 💬 💬 |
1542 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TSLP [1] TSLP 💬 |
Tezepelumab Tezepelumab 💬 |
Tezepelumab | 098 [1] 98 💬 💬 |
1543 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
1544 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
1545 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
1546 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
1547 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
1548 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [2] IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
1549 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
1550 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
1551 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
1552 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
1553 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1554 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |