Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Fat digestion and absorption 💬

[1] MTTP 💬

Lomitapide 💬

[1] 79 💬

2

Fat digestion and absorption 💬

[1] NPC1L1 💬

[4] 49, 79, 93, 260 💬

3

Fatty acid degradation 💬

[3] ADH1A, ADH1B, ADH1C 💬

Fomepizole 💬

[1] 301 💬

4

Fatty acid degradation 💬

[4] CPT1A, CPT1B, CPT1C, CPT2 💬

Perhexiline 💬

[2] 58, 272 💬

5

Fatty acid metabolism 💬

[4] CPT1A, CPT1B, CPT1C, CPT2 💬

Perhexiline 💬

[2] 58, 272 💬

6

Fc epsilon RI signaling pathway 💬

[1] ALOX5 💬

[1] 113 💬

7

Fc epsilon RI signaling pathway 💬

[1] ALOX5 💬

[3] 85, 160, 164 💬

8

Fc epsilon RI signaling pathway 💬

[1] BTK 💬

Acalabrutinib 💬

[2] 46, 61 💬

9

Fc epsilon RI signaling pathway 💬

[1] BTK 💬

Branebrutinib 💬

[3] 46, 49, 53 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;

10

Fc epsilon RI signaling pathway 💬

[1] BTK 💬

Evobrutinib 💬

[3] 13, 46, 49 💬

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