Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
2 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 [1] CD40 💬 |
Bleselumab Bleselumab 💬 |
Bleselumab | 222 [1] 222 💬 💬 |
3 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 [1] CD40 💬 |
Iscalimab Iscalimab 💬 |
Iscalimab | 049 [2] 49, 53 💬 💬 |
4 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 [1] CD40 💬 |
Ravagalimab Ravagalimab 💬 |
Ravagalimab | 053 [2] 53, 97 💬 💬 |
5 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40LG [1] CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 [1] 63 💬 💬 |
6 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
7 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
8 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A [1] IL12A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
9 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
10 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
11 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
12 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
13 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
14 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
15 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
16 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
17 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
18 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
19 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TLR9 [1] TLR9 💬 |
Cobitolimod Cobitolimod 💬 |
Cobitolimod | 097 [1] 97 💬 💬 |
20 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
21 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
22 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
23 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
24 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
25 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
26 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
27 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
28 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
29 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
30 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
31 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
32 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
33 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
34 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
35 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
36 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
37 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
38 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
39 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
40 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
41 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
42 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Flunarizine Flunarizine 💬 |
Flunarizine | 149 [1] 149 💬 💬 |
43 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
44 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Zonisamide Zonisamide 💬 |
Zonisamide | 006 [1] 6 💬 💬 |
45 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
Mirogabalin Mirogabalin 💬 |
Mirogabalin | 070 [1] 70 💬 💬 |
46 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Gabapentin Gabapentin 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 💬 |
47 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Pregabalin Pregabalin 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 💬 |
48 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
49 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
50 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
51 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
52 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
53 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
54 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
55 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
56 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
57 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
58 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
59 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
60 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
61 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
62 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
63 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Axitinib Axitinib 💬 |
Axitinib | 034 [1] 34 💬 💬 |
64 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Cediranib Cediranib 💬 |
Cediranib | 034 [1] 34 💬 💬 |
65 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
66 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
67 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
68 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
69 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
70 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [3] IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
71 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
72 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
73 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
74 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
75 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
76 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
77 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KDR [2] KDR, MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
78 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
79 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
80 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
81 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
82 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
83 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
84 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
85 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
86 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
87 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
88 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
89 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPT [1] MAPT 💬 |
Flortaucipir F 18 Flortaucipir F 18 💬 |
Flortaucipir | 005 [3] 5 , 7 , 127 💬 💬 |
90 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPT [1] MAPT 💬 |
Gosuranemab Gosuranemab 💬 |
Gosuranemab | 005 [1] 5 💬 💬 |
91 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPT [1] MAPT 💬 |
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬 |
Hydromethylthionine mesylate | 127 [1] 127 💬 💬 |
92 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
93 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
NGF [1] NGF 💬 |
Tanezumab Tanezumab 💬 |
Tanezumab | 226 [2] 226, 298 💬 💬 |
94 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
NGFR [1] NGFR 💬 |
Cenegermin Cenegermin 💬 |
Cenegermin | 053 [2] 53, 90 💬 💬 |
95 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PGF [3] PGF, VEGFA, VEGFB 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
96 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
97 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
98 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
99 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
100 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
101 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
102 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
103 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
104 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
105 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
106 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
107 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
108 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
109 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
110 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
111 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
112 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
113 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
114 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
115 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
116 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
117 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
118 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Otelixizumab Otelixizumab 💬 |
Otelixizumab | 046 [1] 46 💬 💬 |
119 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Visilizumab Visilizumab 💬 |
Visilizumab | 096 [2] 96, 97 💬 💬 |
120 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CD3E [1] CD3E 💬 |
Mosunetuzumab Mosunetuzumab 💬 |
Mosunetuzumab | 049 [1] 49 💬 💬 |
121 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
122 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
123 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
124 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 💬 |
125 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 💬 |
126 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 [1] 56 💬 💬 |
127 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 💬 |
128 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 💬 |
129 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 [1] 13 💬 💬 |
130 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 💬 |
131 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
132 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
133 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
134 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [3] IL1A, IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
135 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
136 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
137 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [1] IL2RA 💬 |
Basiliximab Basiliximab 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 💬 |
138 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [1] IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
139 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
Aldesleukin Aldesleukin 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 💬 |
140 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
141 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
142 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
143 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
144 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
145 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
146 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
147 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
148 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
149 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
150 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [2] JAK1, JAK3 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
151 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
152 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
153 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
154 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
155 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
156 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
157 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
TLR7 [1] TLR7 💬 |
Imiquimod Imiquimod 💬 |
Imiquimod | 034 [2] 34, 51 💬 💬 |
158 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
TLR9 [1] TLR9 💬 |
Cobitolimod Cobitolimod 💬 |
Cobitolimod | 097 [1] 97 💬 💬 |
159 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
TYK2 [1] TYK2 💬 |
Deucravacitinib Deucravacitinib 💬 |
Deucravacitinib | 049 [3] 49, 96, 97 💬 💬 |
160 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
161 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
162 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬 |
Macitentan Macitentan 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 💬 |
163 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
164 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
165 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
166 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
167 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
168 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
169 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
170 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [2] KIT, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
171 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
172 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
173 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
174 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
175 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
176 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MC1R [1] MC1R 💬 |
Afamelanotide Afamelanotide 💬 |
Afamelanotide | 159 [3] 159, 161, 254 💬 💬 |
177 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
178 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
179 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
180 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
181 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
182 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
183 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
184 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
185 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
186 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
187 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
188 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
189 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [1] FGFR1 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
190 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
191 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
192 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
193 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
194 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
195 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
196 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
197 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
198 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
199 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
200 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
201 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
202 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
203 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
204 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
205 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
206 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
207 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
208 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [1] ABAT 💬 |
Vigabatrin Vigabatrin 💬 |
Vigabatrin | 145 [2] 145, 158 💬 💬 |
209 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
210 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
Fomepizole Fomepizole 💬 |
Fomepizole | 301 [1] 301 💬 💬 |
211 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALAS1 [1] ALAS1 💬 |
Givosiran Givosiran 💬 |
Givosiran | 254 [1] 254 💬 💬 |
212 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALAS1 [2] ALAS1, ALAS2 💬 |
Hemin Hemin 💬 |
Hemin | 254 [1] 254 💬 💬 |
213 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬 |
Oxatomide Oxatomide 💬 |
Oxatomide | 113 [1] 113 💬 💬 |
214 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬 |
Zileuton Zileuton 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 💬 |
215 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALPL [1] ALPL 💬 |
Asfotase alfa Asfotase alfa 💬 |
Asfotase alfa | 172 [1] 172 💬 💬 |
216 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
Acarbose Acarbose 💬 |
Acarbose | 298 [1] 298 💬 💬 |
217 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ANPEP [1] ANPEP 💬 |
Ubenimex Ubenimex 💬 |
Ubenimex | 086 [1] 86 💬 💬 |
218 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
AOC3 [1] AOC3 💬 |
Hydralazine Hydralazine 💬 |
Hydralazine | 067 [1] 67 💬 💬 |
219 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ARSB [1] ARSB 💬 |
Galsulfase Galsulfase 💬 |
Galsulfase | 019 [1] 19 💬 💬 |
220 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Dexlansoprazole Dexlansoprazole 💬 |
Dexlansoprazole | 098 [1] 98 💬 💬 |
221 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Esomeprazole Esomeprazole 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 💬 |
222 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 💬 |
223 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Omeprazole Omeprazole 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 💬 |
224 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Pantoprazole Pantoprazole 💬 |
Pantoprazole | 013 [2] 13, 65 💬 💬 |
225 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Rabeprazole Rabeprazole 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 💬 |
226 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 [2] 63, 98 💬 💬 |
227 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Acetazolamide Acetazolamide 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬 |
228 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Dichlorphenamide Dichlorphenamide 💬 |
Diclofenamide | 114 [1] 114 💬 💬 |
229 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Dorzolamide Dorzolamide 💬 |
Dorzolamide | 090 [1] 90 💬 💬 |
230 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
231 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬 💬 |
232 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 [3] 28, 61, 283 💬 💬 |
233 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 [2] 63, 66 💬 💬 |
234 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Entacapone Entacapone 💬 |
Entacapone | 006 [2] 6 , 17 💬 💬 |
235 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Opicapone Opicapone 💬 |
Opicapone | 006 [1] 6 💬 💬 |
236 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Tolcapone Tolcapone 💬 |
Tolcapone | 006 [3] 6 , 28, 127 💬 💬 |
237 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CPS1 [1] CPS1 💬 |
Carglumic acid Carglumic acid 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 💬 |
238 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11A1 [3] CYP11A1, CYP11B1, CYP17A1 💬 |
Levoketoconazole Levoketoconazole 💬 |
Levoketoconazole | 075 [1] 75 💬 💬 |
239 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11B1 [1] CYP11B1 💬 |
Metyrapone Metyrapone 💬 |
Metyrapone | 075 [1] 75 💬 💬 |
240 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11B2 [1] CYP11B2 💬 |
Osilodrostat Osilodrostat 💬 |
Osilodrostat | 075 [1] 75 💬 💬 |
241 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP17A1 [1] CYP17A1 💬 |
Ketoconazole Ketoconazole 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 💬 |
242 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP19A1 [1] CYP19A1 💬 |
Anastrozole Anastrozole 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 💬 |
243 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP19A1 [1] CYP19A1 💬 |
Letrozole Letrozole 💬 |
Letrozole | 081 [2] 81, 89 💬 💬 |
244 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DDC [1] DDC 💬 |
Benserazide Benserazide 💬 |
Benserazide | 006 [1] 6 💬 💬 |
245 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
246 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR [2] DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
247 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHODH [1] DHODH 💬 |
Leflunomide Leflunomide 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 💬 |
248 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHODH [1] DHODH 💬 |
Teriflunomide Teriflunomide 💬 |
Teriflunomide | 013 [3] 13, 25, 26 💬 💬 |
249 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 💬 |
250 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ENPP2 [1] ENPP2 💬 |
Ziritaxestat Ziritaxestat 💬 |
Ziritaxestat | 051 [2] 51, 85 💬 💬 |
251 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Alendronic acid Alendronic acid 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 💬 |
252 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Pamidronic acid Pamidronic acid 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 💬 |
253 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Risedronic acid Risedronic acid 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 💬 |
254 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Zoledronic acid Zoledronic acid 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 💬 |
255 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Zoledronic acid Zoledronic acid 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 💬 |
256 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Alglucosidase alfa Alglucosidase alfa 💬 |
Alglucosidase alfa | 256 [1] 256 💬 💬 |
257 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Avalglucosidase alfa Avalglucosidase alfa 💬 |
Avalglucosidase alfa | 256 [1] 256 💬 💬 |
258 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Cipaglucosidase alfa Cipaglucosidase alfa 💬 |
Cipaglucosidase alfa | 256 [1] 256 💬 💬 |
259 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Duvoglustat Duvoglustat 💬 |
Duvoglustat | 256 [1] 256 💬 💬 |
260 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GALNS [1] GALNS 💬 |
Elosulfase alfa Elosulfase alfa 💬 |
Elosulfase alfa | 019 [1] 19 💬 💬 |
261 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Alglucerase Alglucerase 💬 |
Alglucerase | 019 [1] 19 💬 💬 |
262 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Imiglucerase Imiglucerase 💬 |
Imiglucerase | 019 [1] 19 💬 💬 |
263 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Taliglucerase alfa Taliglucerase alfa 💬 |
Taliglucerase alfa | 019 [1] 19 💬 💬 |
264 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Velaglucerase alfa Velaglucerase alfa 💬 |
Velaglucerase alfa | 019 [1] 19 💬 💬 |
265 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GLA [1] GLA 💬 |
Agalsidase alfa Agalsidase alfa 💬 |
Agalsidase alfa | 019 [1] 19 💬 💬 |
266 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GLA [1] GLA 💬 |
Agalsidase beta Agalsidase beta 💬 |
Agalsidase beta | 019 [1] 19 💬 💬 |
267 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
268 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
269 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY2C [1] GUCY2C 💬 |
Linaclotide Linaclotide 💬 |
Linaclotide | 006 [2] 6 , 97 💬 💬 |
270 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUSB [1] GUSB 💬 |
Vestronidase alfa Vestronidase alfa 💬 |
Vestronidase alfa | 019 [1] 19 💬 💬 |
271 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HAO1 [1] HAO1 💬 |
Lumasiran Lumasiran 💬 |
Lumasiran | 234 [1] 234 💬 💬 |
272 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
273 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Fluvastatin Fluvastatin 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 💬 |
274 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Lovastatin Lovastatin 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬 |
275 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
276 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Rosuvastatin Rosuvastatin 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 💬 |
277 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
278 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMOX1 [2] HMOX1, HMOX2 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
279 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPD [1] HPD 💬 |
Nitisinone Nitisinone 💬 |
Nitisinone | 006 [3] 6 , 164, 241 💬 💬 |
280 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
281 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
282 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
283 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Idursulfase Idursulfase 💬 |
Idursulfase | 019 [1] 19 💬 💬 |
284 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Idursulfase beta Idursulfase beta 💬 |
Idursulfase beta | 019 [1] 19 💬 💬 |
285 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Pabinafusp alfa Pabinafusp alfa 💬 |
Pabinafusp alfa | 019 [1] 19 💬 💬 |
286 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDUA [1] IDUA 💬 |
Laronidase Laronidase 💬 |
Laronidase | 019 [2] 19, 256 💬 💬 |
287 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mizoribine Mizoribine 💬 |
Mizoribine | 046 [8] 46, 49, 51, 53, 66, 94, 222, 224 💬 💬 |
288 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬 |
289 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
290 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [1] MAOA 💬 |
Moclobemide Moclobemide 💬 |
Moclobemide | 006 [1] 6 💬 💬 |
291 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Iproniazid Iproniazid 💬 |
Iproniazid | 006 [1] 6 💬 💬 |
292 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phenelzine Phenelzine 💬 |
Phenelzine | 006 [1] 6 💬 💬 |
293 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
294 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Rasagiline Rasagiline 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
295 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Rasagiline tartrate Rasagiline tartrate 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
296 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Safinamide Safinamide 💬 |
Safinamide | 006 [2] 6 , 17 💬 💬 |
297 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Selegiline Selegiline 💬 |
Selegiline | 006 [1] 6 💬 💬 |
298 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR1 [1] NPR1 💬 |
Nesiritide Nesiritide 💬 |
Nesiritide | 046 [2] 46, 58 💬 💬 |
299 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR1 [2] NPR1, NPR2 💬 |
Erythrityl tetranitrate Erythrityl tetranitrate 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 💬 |
300 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR2 [1] NPR2 💬 |
Vosoritide Vosoritide 💬 |
Vosoritide | 276 [1] 276 💬 💬 |
301 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
Warfarin Warfarin 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬 |
302 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ODC1 [1] ODC1 💬 |
Eflornithine Eflornithine 💬 |
Eflornithine | 065 [1] 65 💬 💬 |
303 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PAH [1] PAH 💬 |
Pegvaliase Pegvaliase 💬 |
Pegvaliase | 240 [1] 240 💬 💬 |
304 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
305 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
306 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
307 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
308 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
309 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
310 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
311 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
312 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
313 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
314 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
315 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
316 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
317 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
318 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [2] PDE4A, PDE5A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
319 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
320 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
321 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
322 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Udenafil Udenafil 💬 |
Udenafil | 086 [2] 86, 210 💬 💬 |
323 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Vardenafil Vardenafil 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 💬 |
324 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
325 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
326 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
327 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGES [3] PTGES, PTGS1, PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
328 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
329 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
330 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
331 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
332 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
333 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
334 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
335 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
336 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
337 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
338 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
339 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
340 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
341 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
342 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
343 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
344 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
345 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
346 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
347 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
348 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
349 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
350 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
351 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Cladribine Cladribine 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 💬 |
352 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Clofarabine Clofarabine 💬 |
Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬 💬 |
353 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
354 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
355 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SMPD1 [1] SMPD1 💬 |
Olipudase alfa Olipudase alfa 💬 |
Olipudase alfa | 019 [1] 19 💬 💬 |
356 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬 |
Dutasteride Dutasteride 💬 |
Dutasteride | 001 [2] 1 , 2 💬 💬 |
357 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SRD5A2 [1] SRD5A2 💬 |
Finasteride Finasteride 💬 |
Finasteride | 006 [1] 6 💬 💬 |
358 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TPH1 [2] TPH1, TPH2 💬 |
Telotristat Telotristat 💬 |
Telotristat | 097 [1] 97 💬 💬 |
359 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TPO [1] TPO 💬 |
Methimazole Methimazole 💬 |
Methimazole | 050 [1] 50 💬 💬 |
360 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TYMS [1] TYMS 💬 |
Tegafur Tegafur 💬 |
Tegafur | 046 [1] 46 💬 💬 |
361 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Eliglustat Eliglustat 💬 |
Eliglustat | 019 [1] 19 💬 💬 |
362 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Lucerastat Lucerastat 💬 |
Lucerastat | 019 [1] 19 💬 💬 |
363 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Miglustat Miglustat 💬 |
Miglustat | 019 [3] 19, 256, 299 💬 💬 |
364 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Venglustat Venglustat 💬 |
Venglustat | 006 [3] 6 , 19, 67 💬 💬 |
365 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
VKORC1 [1] VKORC1 💬 |
Phenindione Phenindione 💬 |
Phenindione | 065 [1] 65 💬 💬 |
366 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
367 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬 |
Febuxostat Febuxostat 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 💬 |
368 | Metabolism of xenobiotics by cytochrome P450 💬 3 genes, 1 drug (DrugBank) and 1 disease |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
Fomepizole Fomepizole 💬 |
Fomepizole | 301 [1] 301 💬 💬 |
369 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [1] ABL1 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
370 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
371 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
372 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
373 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
374 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
375 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
376 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
CDK6 [1] CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
377 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 💬 |
378 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
379 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
380 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
381 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
382 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
383 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
384 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
385 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
FGFR3 [1] FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
386 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
387 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
HDAC1 [4] HDAC1, HDAC2, HDAC4, HDAC5 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 [2] 75, 96 💬 💬 |
388 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
HMOX1 [1] HMOX1 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
389 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
390 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
391 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
392 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
393 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
394 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
395 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
396 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
397 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
398 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
399 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
400 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
401 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
402 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
403 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
404 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
405 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PRKCE [1] PRKCE 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
406 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
407 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
408 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
409 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
410 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
411 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
412 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
413 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
414 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
415 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
416 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
417 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
418 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
419 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
420 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
421 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
422 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
423 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
424 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
425 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
426 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
427 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
428 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
429 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
430 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ROCK1 [1] ROCK1 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
431 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
TGFB2 [1] TGFB2 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
432 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
433 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
434 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
435 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
436 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
437 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
CLCN2 [1] CLCN2 💬 |
Lubiprostone Lubiprostone 💬 |
Lubiprostone | 006 [4] 6 , 13, 290, 299 💬 💬 |
438 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
HMOX1 [2] HMOX1, HMOX2 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
439 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Alfacalcidol Alfacalcidol 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 💬 |
440 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Calcifediol Calcifediol 💬 |
Calcifediol | 113 [2] 113, 299 💬 💬 |
441 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Calcipotriene Calcipotriene 💬 |
Calcipotriol | 036 [2] 36, 51 💬 💬 |
442 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
443 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
444 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Dihydrotachysterol Dihydrotachysterol 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 💬 |
445 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Eldecalcitol Eldecalcitol 💬 |
Eldecalcitol | 046 [1] 46 💬 💬 |
446 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 💬 |
447 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Paricalcitol Paricalcitol 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 💬 |
448 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
449 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
450 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
451 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
452 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
453 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬 |
Adenosine Adenosine 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 💬 |
454 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬 |
Adenosine phosphate Adenosine phosphate 💬 |
Adenosine phosphate | 046 [1] 46 💬 💬 |
455 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
456 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
457 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
458 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
459 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
460 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
CACNA1B [1] CACNA1B 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
461 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Apomorphine Apomorphine 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 💬 |
462 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Dexpramipexole Dexpramipexole 💬 |
Dexpramipexole | 002 [1] 2 💬 💬 |
463 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Dopamine Dopamine 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 💬 |
464 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Flupentixol Flupentixol 💬 |
Flupentixol | 097 [1] 97 💬 💬 |
465 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Foslevodopa Foslevodopa 💬 |
Foslevodopa | 006 [1] 6 💬 💬 |
466 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
467 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Pergolide Pergolide 💬 |
Pergolide | 006 [1] 6 💬 💬 |
468 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Tavapadon Tavapadon 💬 |
Tavapadon | 006 [1] 6 💬 💬 |
469 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Arbaclofen Arbaclofen 💬 |
Arbaclofen | 013 [2] 13, 206 💬 💬 |
470 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Arbaclofen placarbil Arbaclofen placarbil 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 💬 |
471 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
472 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Valiloxybate Valiloxybate 💬 |
Valiloxybate | 006 [1] 6 💬 💬 |
473 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [1] GABRA1 💬 |
Etomidate Etomidate 💬 |
Etomidate | 006 [1] 6 💬 💬 |
474 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Alprazolam Alprazolam 💬 |
Alprazolam | 008 [2] 8 , 75 💬 💬 |
475 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Brexanolone Brexanolone 💬 |
Brexanolone | 205 [1] 205 💬 💬 |
476 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
477 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clonazepam Clonazepam 💬 |
Clonazepam | 006 [1] 6 💬 💬 |
478 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Delorazepam Delorazepam 💬 |
Delorazepam | 006 [3] 6 , 46, 97 💬 💬 |
479 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Diazepam Diazepam 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 💬 |
480 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Eszopiclone Eszopiclone 💬 |
Eszopiclone | 006 [3] 6 , 13, 46 💬 💬 |
481 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Flumazenil Flumazenil 💬 |
Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬 💬 |
482 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Gaboxadol Gaboxadol 💬 |
Gaboxadol | 201 [2] 201, 206 💬 💬 |
483 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Ganaxolone Ganaxolone 💬 |
Ganaxolone | 145 [4] 145, 152, 158, 206 💬 💬 |
484 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Lorazepam Lorazepam 💬 |
Lorazepam | 036 [1] 36 💬 💬 |
485 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
486 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Propofol Propofol 💬 |
Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 💬 |
487 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
488 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Zolpidem Zolpidem 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 💬 |
489 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Zopiclone Zopiclone 💬 |
Zopiclone | 006 [1] 6 💬 💬 |
490 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
491 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Buprenorphine Buprenorphine 💬 |
Buprenorphine | 046 [2] 46, 70 💬 💬 |
492 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Dezocine Dezocine 💬 |
Dezocine | 046 [1] 46 💬 💬 |
493 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Dihydrocodeine Dihydrocodeine 💬 |
Dihydrocodeine | 310 [1] 310 💬 💬 |
494 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Fentanyl Fentanyl 💬 |
Fentanyl | 046 [3] 46, 70, 215 💬 💬 |
495 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Hydromorphone Hydromorphone 💬 |
Hydromorphone | 070 [1] 70 💬 💬 |
496 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Loperamide Loperamide 💬 |
Loperamide | 013 [2] 13, 97 💬 💬 |
497 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Morphine Morphine 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 💬 |
498 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Nalbuphine Nalbuphine 💬 |
Nalbuphine | 085 [1] 85 💬 💬 |
499 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Nalmefene Nalmefene 💬 |
Nalmefene | 006 [1] 6 💬 💬 |
500 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Naloxone Naloxone 💬 |
Naloxone | 006 [2] 6 , 226 💬 💬 |
501 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
502 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Oxycodone Oxycodone 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 💬 |
503 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Oxymorphone Oxymorphone 💬 |
Oxymorphone | 070 [1] 70 💬 💬 |
504 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Remifentanil Remifentanil 💬 |
Remifentanil | 006 [2] 6 , 70 💬 💬 |
505 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Sufentanil Sufentanil 💬 |
Sufentanil | 070 [2] 70, 280 💬 💬 |
506 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Tramadol Tramadol 💬 |
Tramadol | 046 [5] 46, 70, 78, 226, 271 💬 💬 |
507 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Trimebutine Trimebutine 💬 |
Trimebutine | 051 [1] 51 💬 💬 |
508 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
509 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
510 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
511 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
512 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
513 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
514 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [1] PDE4A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
515 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
516 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
517 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
518 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
519 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
520 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
521 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
522 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
523 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
524 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
525 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
526 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
527 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
528 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
529 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
530 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
531 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
532 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
533 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
534 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
535 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
536 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
537 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
538 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
539 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
540 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
541 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
542 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
543 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
544 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
545 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
546 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
547 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
548 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
549 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
550 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
551 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |