Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [1] ADRA1A 💬
|
Alfuzosin Alfuzosin 💬
| Alfuzosin | 013 [1] 13 💬
|
| 2 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [1] ADRA1A 💬
|
Silodosin Silodosin 💬
| Silodosin | 006 [2] 6 , 13 💬
|
| 3 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Doxazosin Doxazosin 💬
| Doxazosin | 057 [2] 57, 67 💬
|
| 4 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 [1] 280 💬
|
| 5 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Midodrine Midodrine 💬
| Midodrine | 006 [3] 6 , 17, 58 💬
|
| 6 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 7 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Phenylephrine Phenylephrine 💬
| Phenylephrine | 022 [1] 22 💬
|
| 8 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Tamsulosin Tamsulosin 💬
| Tamsulosin | 013 [1] 13 💬
|
| 9 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Terazosin Terazosin 💬
| Terazosin | 006 [1] 6 💬
|
| 10 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 [2] 28, 127 💬
|
| 11 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
|
Carvedilol Carvedilol 💬
| Carvedilol | 057 [4] 57, 86, 113, 210 💬
|
| 12 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Dipivefrin Dipivefrin 💬
| Dipivefrin | 006 [1] 6 💬
|
| 13 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Droxidopa Droxidopa 💬
| Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬
|
| 14 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Ephedrine Ephedrine 💬
| Ephedrine | 011 [1] 11 💬
|
| 15 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Epinephrine Epinephrine 💬
| Epinephrine | 046 [3] 46, 70, 96 💬
|
| 16 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Noradrenaline Noradrenaline 💬
| Norepinephrine | 022 [2] 22, 296 💬
|
| 17 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬
|
Pseudoephedrine Pseudoephedrine 💬
| Pseudoephedrine | 017 [1] 17 💬
|
| 18 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Atenolol Atenolol 💬
| Atenolol | 167 [1] 167 💬
|
| 19 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Bisoprolol Bisoprolol 💬
| Bisoprolol | 058 [4] 58, 67, 86, 113 💬
|
| 20 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Celiprolol Celiprolol 💬
| Celiprolol | 168 [1] 168 💬
|
| 21 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Dobutamine Dobutamine 💬
| Dobutamine | 057 [4] 57, 58, 86, 215 💬
|
| 22 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Esmolol Esmolol 💬
| Esmolol | 058 [1] 58 💬
|
| 23 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Metoprolol Metoprolol 💬
| Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬
|
| 24 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 25 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Nadolol Nadolol 💬
| Nadolol | 006 [1] 6 💬
|
| 26 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Timolol Timolol 💬
| Timolol | 157 [2] 157, 227 💬
|
| 27 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Timolol Timolol 💬
| Timolol | 157 [2] 157, 227 💬
|
| 28 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬
|
Propranolol Propranolol 💬
| Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬
|
| 29 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 30 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 31 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Isoxsuprine Isoxsuprine 💬
| Isoxsuprine | 013 [1] 13 💬
|
| 32 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Levosalbutamol Levosalbutamol 💬
| Levosalbutamol | 049 [1] 49 💬
|
| 33 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 34 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Salmeterol Salmeterol 💬
| Salmeterol | 299 [1] 299 💬
|
| 35 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Terbutaline Terbutaline 💬
| Terbutaline | 118 [1] 118 💬
|
| 36 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Tulobuterol Tulobuterol 💬
| Tulobuterol | 006 [1] 6 💬
|
| 37 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB3 [1] ADRB3 💬
|
Mirabegron Mirabegron 💬
| Mirabegron | 006 [4] 6 , 13, 53, 226 💬
|
| 38 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
AMY2A [2] AMY2A, AMY2B 💬
|
Acarbose Acarbose 💬
| Acarbose | 298 [1] 298 💬
|
| 39 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digitoxin Digitoxin 💬
| Digitoxin | 299 [1] 299 💬
|
| 40 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
| 41 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CD38 [1] CD38 💬
|
Daratumumab Daratumumab 💬
| Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬
|
| 42 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CD38 [1] CD38 💬
|
Isatuximab Isatuximab 💬
| Isatuximab | 028 [3] 28, 61, 283 💬
|
| 43 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CD38 [1] CD38 💬
|
Mezagitamab Mezagitamab 💬
| Mezagitamab | 063 [2] 63, 66 💬
|
| 44 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 45 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Blarcamesine Blarcamesine 💬
| Blarcamesine | 156 [1] 156 💬
|
| 46 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Cevimeline Cevimeline 💬
| Cevimeline | 053 [1] 53 💬
|
| 47 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Chlorpromazine Chlorpromazine 💬
| Chlorpromazine | 254 [1] 254 💬
|
| 48 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Darifenacin Darifenacin 💬
| Darifenacin | 006 [2] 6 , 13 💬
|
| 49 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Fesoterodine Fesoterodine 💬
| Fesoterodine | 006 [1] 6 💬
|
| 50 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Oxybutynin Oxybutynin 💬
| Oxybutynin | 006 [3] 6 , 13, 53 💬
|
| 51 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Pilocarpine Pilocarpine 💬
| Pilocarpine | 006 [3] 6 , 53, 299 💬
|
| 52 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 [1] 226 💬
|
| 53 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 54 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Solifenacin Solifenacin 💬
| Solifenacin | 006 [3] 6 , 13, 53 💬
|
| 55 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Tolterodine Tolterodine 💬
| Tolterodine | 017 [2] 17, 53 💬
|
| 56 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Trihexyphenidyl Trihexyphenidyl 💬
| Trihexyphenidyl | 005 [2] 5 , 6 💬
|
| 57 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Tropicamide Tropicamide 💬
| Tropicamide | 006 [1] 6 💬
|
| 58 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
|
Amyl nitrite Amyl nitrite 💬
| Amyl Nitrite | 058 [1] 58 💬
|
| 59 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
|
Riociguat Riociguat 💬
| Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
|
| 60 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
| 61 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
SLC12A2 [1] SLC12A2 💬
|
Bumetanide Bumetanide 💬
| Bumetanide | 006 [2] 6 , 158 💬
|
| 62 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
SLC12A2 [1] SLC12A2 💬
|
Furosemide Furosemide 💬
| Furosemide | 006 [2] 6 , 86 💬
|
| 63 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
| 64 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 65 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
| 66 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
| 67 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 68 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 [2] 46, 96 💬
|
| 69 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 [2] 28, 331 💬
|
| 70 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 [2] 41, 46 💬
|
| 71 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 72 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
| 73 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
| 74 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
| 75 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
| 76 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 77 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
| 78 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
| 79 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
| 80 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 81 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 82 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 83 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
| 84 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
| 85 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 86 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
ROCK2 [1] ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 87 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TLR9 [1] TLR9 💬
|
Cobitolimod Cobitolimod 💬
| Cobitolimod | 097 [1] 97 💬
|
| 88 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
| 89 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
| 90 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 91 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 92 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 93 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 94 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
| 95 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
| 96 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 97 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Belantamab mafodotin Belantamab mafodotin 💬
| Belantamab mafodotin | 028 [1] 28 💬
|
| 98 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Brentuximab vedotin Brentuximab vedotin 💬
| Brentuximab vedotin | 049 [2] 49, 51 💬
|
| 99 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 100 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 101 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
| 102 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
| 103 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
ALOX5 [1] ALOX5 💬
|
Oxatomide Oxatomide 💬
| Oxatomide | 113 [1] 113 💬
|
| 104 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 105 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
| 106 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
| 107 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Cilnidipine Cilnidipine 💬
| Cilnidipine | 067 [1] 67 💬
|
| 108 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Amlodipine Amlodipine 💬
| Amlodipine | 013 [4] 13, 51, 67, 298 💬
|
| 109 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Diltiazem Diltiazem 💬
| Diltiazem | 051 [3] 51, 58, 86 💬
|
| 110 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Isradipine Isradipine 💬
| Isradipine | 006 [1] 6 💬
|
| 111 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nicardipine Nicardipine 💬
| Nicardipine | 070 [2] 70, 86 💬
|
| 112 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 [2] 50, 81 💬
|
| 113 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nilvadipine Nilvadipine 💬
| Nilvadipine | 090 [1] 90 💬
|
| 114 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Perhexiline Perhexiline 💬
| Perhexiline | 058 [2] 58, 272 💬
|
| 115 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 [1] 226 💬
|
| 116 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Verapamil Verapamil 💬
| Verapamil | 058 [4] 58, 96, 140, 167 💬
|
| 117 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬
|
| 118 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
DDC [1] DDC 💬
|
Benserazide Benserazide 💬
| Benserazide | 006 [1] 6 💬
|
| 119 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
DDC [1] DDC 💬
|
Carbidopa Carbidopa 💬
| Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬
|
| 120 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
| 121 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Brexanolone Brexanolone 💬
| Brexanolone | 205 [1] 205 💬
|
| 122 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Clobazam Clobazam 💬
| Clobazam | 140 [2] 140, 144 💬
|
| 123 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Clonazepam Clonazepam 💬
| Clonazepam | 006 [1] 6 💬
|
| 124 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Delorazepam Delorazepam 💬
| Delorazepam | 006 [3] 6 , 46, 97 💬
|
| 125 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Diazepam Diazepam 💬
| Diazepam | 046 [3] 46, 155, 298 💬
|
| 126 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Eszopiclone Eszopiclone 💬
| Eszopiclone | 006 [3] 6 , 13, 46 💬
|
| 127 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Flumazenil Flumazenil 💬
| Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬
|
| 128 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Gaboxadol Gaboxadol 💬
| Gaboxadol | 201 [2] 201, 206 💬
|
| 129 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Ganaxolone Ganaxolone 💬
| Ganaxolone | 145 [4] 145, 152, 158, 206 💬
|
| 130 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Lorazepam Lorazepam 💬
| Lorazepam | 036 [1] 36 💬
|
| 131 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 132 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
| 133 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Zolpidem Zolpidem 💬
| Zolpidem | 005 [3] 5 , 6 , 46 💬
|
| 134 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Zopiclone Zopiclone 💬
| Zopiclone | 006 [1] 6 💬
|
| 135 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1A [1] HTR1A 💬
|
Buspirone Buspirone 💬
| Buspirone | 006 [2] 6 , 51 💬
|
| 136 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1A [1] HTR1A 💬
|
Pardoprunox Pardoprunox 💬
| Pardoprunox | 006 [1] 6 💬
|
| 137 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1A [2] HTR1A, HTR2A 💬
|
Aripiprazole Aripiprazole 💬
| Aripiprazole | 006 [2] 6 , 206 💬
|
| 138 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1A [2] HTR1A, HTR2A 💬
|
Cariprazine Cariprazine 💬
| Cariprazine | 021 [1] 21 💬
|
| 139 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1A [7] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E, SLC6A4 💬
|
Vortioxetine Vortioxetine 💬
| Vortioxetine | 006 [1] 6 💬
|
| 140 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1B [2] HTR1B, HTR1D 💬
|
Zolmitriptan Zolmitriptan 💬
| Zolmitriptan | 006 [1] 6 💬
|
| 141 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1D [4] HTR1D, HTR2A, HTR2C, SLC6A4 💬
|
Fenfluramine Fenfluramine 💬
| Fenfluramine | 140 [4] 140, 144, 145, 149 💬
|
| 142 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [1] HTR2A 💬
|
Nelotanserin Nelotanserin 💬
| Nelotanserin | 006 [1] 6 💬
|
| 143 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [1] HTR2A 💬
|
Quetiapine Quetiapine 💬
| Quetiapine | 006 [2] 6 , 13 💬
|
| 144 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
| 145 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Chlorpromazine Chlorpromazine 💬
| Chlorpromazine | 254 [1] 254 💬
|
| 146 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Iloperidone Iloperidone 💬
| Iloperidone | 006 [1] 6 💬
|
| 147 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 148 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 149 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [7] HTR2A, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬
|
Clozapine Clozapine 💬
| Clozapine | 006 [1] 6 💬
|
| 150 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [3] HTR2A, HTR3A, HTR4 💬
|
Cisapride Cisapride 💬
| Cisapride | 013 [1] 13 💬
|
| 151 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [3] HTR2A, HTR3A, HTR4 💬
|
Cisapride Cisapride 💬
| Cisapride | 013 [1] 13 💬
|
| 152 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2C [1] HTR2C 💬
|
Agomelatine Agomelatine 💬
| Agomelatine | 006 [1] 6 💬
|
| 153 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬
|
Dolasetron Dolasetron 💬
| Dolasetron | 046 [1] 46 💬
|
| 154 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬
|
Ondansetron Ondansetron 💬
| Ondansetron | 006 [3] 6 , 97, 107 💬
|
| 155 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR4 [1] HTR4 💬
|
Mosapride Mosapride 💬
| Mosapride | 096 [1] 96 💬
|
| 156 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR4 [1] HTR4 💬
|
Prucalopride Prucalopride 💬
| Prucalopride | 013 [3] 13, 51, 96 💬
|
| 157 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR4 [1] HTR4 💬
|
Velusetrag Velusetrag 💬
| Velusetrag | 099 [1] 99 💬
|
| 158 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCND2 [1] KCND2 💬
|
Amifampridine Amifampridine 💬
| Amifampridine | 003 [3] 3 , 11, 12 💬
|
| 159 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCND2 [1] KCND2 💬
|
Dalfampridine Dalfampridine 💬
| Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬
|
| 160 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCNJ3 [2] KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 [2] 28, 127 💬
|
| 161 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOA [1] MAOA 💬
|
Moclobemide Moclobemide 💬
| Moclobemide | 006 [1] 6 💬
|
| 162 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOA [2] MAOA, MAOB 💬
|
Iproniazid Iproniazid 💬
| Iproniazid | 006 [1] 6 💬
|
| 163 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOA [2] MAOA, MAOB 💬
|
Phenelzine Phenelzine 💬
| Phenelzine | 006 [1] 6 💬
|
| 164 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOA [3] MAOA, MAOB, SLC6A4 💬
|
Phentermine Phentermine 💬
| Phentermine | 097 [1] 97 💬
|
| 165 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 166 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 167 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Safinamide Safinamide 💬
| Safinamide | 006 [2] 6 , 17 💬
|
| 168 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Selegiline Selegiline 💬
| Selegiline | 006 [1] 6 💬
|
| 169 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
| 170 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
| 171 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
| 172 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
| 173 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 174 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
| 175 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Aceclofenac Aceclofenac 💬
| Aceclofenac | 046 [1] 46 💬
|
| 176 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
| 177 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Aspirin Aspirin 💬
| Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
|
| 178 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
| 179 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Flurbiprofen Flurbiprofen 💬
| Flurbiprofen | 013 [3] 13, 21, 46 💬
|
| 180 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Ibuprofen Ibuprofen 💬
| Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬
|
| 181 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Indomethacin Indomethacin 💬
| Indomethacin | 225 [3] 225, 271, 298 💬
|
| 182 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Ketoprofen Ketoprofen 💬
| Ketoprofen | 046 [1] 46 💬
|
| 183 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Ketorolac Ketorolac 💬
| Ketorolac | 070 [2] 70, 226 💬
|
| 184 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Loxoprofen Loxoprofen 💬
| Loxoprofen | 046 [2] 46, 271 💬
|
| 185 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Naproxen Naproxen 💬
| Naproxen | 013 [4] 13, 46, 107, 271 💬
|
| 186 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Salsalate Salsalate 💬
| Salsalate | 005 [1] 5 💬
|
| 187 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Sulindac Sulindac 💬
| Sulindac | 206 [1] 206 💬
|
| 188 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Tolfenamic acid Tolfenamic acid 💬
| Tolfenamic acid | 005 [1] 5 💬
|
| 189 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 190 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Diflunisal Diflunisal 💬
| Diflunisal | 028 [1] 28 💬
|
| 191 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Etodolac Etodolac 💬
| Etodolac | 046 [1] 46 💬
|
| 192 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Etoricoxib Etoricoxib 💬
| Etoricoxib | 046 [2] 46, 271 💬
|
| 193 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Lumiracoxib Lumiracoxib 💬
| Lumiracoxib | 046 [1] 46 💬
|
| 194 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Meloxicam Meloxicam 💬
| Meloxicam | 046 [4] 46, 49, 271, 296 💬
|
| 195 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Nimesulide Nimesulide 💬
| Nimesulide | 046 [1] 46 💬
|
| 196 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Parecoxib Parecoxib 💬
| Parecoxib | 046 [2] 46, 271 💬
|
| 197 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Rofecoxib Rofecoxib 💬
| Rofecoxib | 046 [1] 46 💬
|
| 198 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Valdecoxib Valdecoxib 💬
| Valdecoxib | 046 [1] 46 💬
|
| 199 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
| 200 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
| 201 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
| 202 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Amitriptyline Amitriptyline 💬
| Amitriptyline | 078 [4] 78, 97, 226, 299 💬
|
| 203 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Amoxapine Amoxapine 💬
| Amoxapine | 046 [1] 46 💬
|
| 204 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Ampreloxetine Ampreloxetine 💬
| Ampreloxetine | 006 [2] 6 , 17 💬
|
| 205 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬
|
| 206 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Desipramine Desipramine 💬
| Desipramine | 120 [2] 120, 156 💬
|
| 207 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Doxepin Doxepin 💬
| Doxepin | 006 [1] 6 💬
|
| 208 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Duloxetine Duloxetine 💬
| Duloxetine | 006 [2] 6 , 13 💬
|
| 209 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Escitalopram Escitalopram 💬
| Escitalopram | 002 [4] 2 , 6 , 13, 46 💬
|
| 210 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Fluoxetine Fluoxetine 💬
| Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
|
| 211 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Milnacipran Milnacipran 💬
| Milnacipran | 046 [2] 46, 49 💬
|
| 212 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Nortriptyline Nortriptyline 💬
| Nortriptyline | 006 [2] 6 , 226 💬
|
| 213 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
| 214 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Sertraline Sertraline 💬
| Sertraline | 006 [2] 6 , 206 💬
|
| 215 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Venlafaxine Venlafaxine 💬
| Venlafaxine | 006 [3] 6 , 13, 46 💬
|
| 216 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
TPH1 [2] TPH1, TPH2 💬
|
Telotristat Telotristat 💬
| Telotristat | 097 [1] 97 💬
|
| 217 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
| 218 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 219 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
CSF2 [1] CSF2 💬
|
Otilimab Otilimab 💬
| Otilimab | 046 [1] 46 💬
|
| 220 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 [2] 51, 86 💬
|
| 221 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 [1] 94 💬
|
| 222 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 [1] 75 💬
|
| 223 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
| 224 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 225 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 226 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 227 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 228 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
| 229 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
| 230 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 231 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 232 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
| 233 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
| 234 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
| 235 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 236 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 [1] 13 💬
|
| 237 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
| 238 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 239 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 240 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 241 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
PRKCD [3] PRKCD, PRKCE, PRKCQ 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 [1] 97 💬
|
| 242 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
| 243 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 244 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 245 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 246 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 247 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 248 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 [3] 6 , 89, 272 💬
|
| 249 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
| 250 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
| 251 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 252 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 253 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 254 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 255 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
| 256 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
| 257 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 258 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 259 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
ACVR2A [1] ACVR2A 💬
|
Sotatercept Sotatercept 💬
| Sotatercept | 086 [2] 86, 284 💬
|
| 260 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
ACVR2A [2] ACVR2A, ACVR2B 💬
|
Bimagrumab Bimagrumab 💬
| Bimagrumab | 015 [1] 15 💬
|
| 261 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
ACVR2B [1] ACVR2B 💬
|
Luspatercept Luspatercept 💬
| Luspatercept | 060 [1] 60 💬
|
| 262 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
|
Infigratinib Infigratinib 💬
| Infigratinib | 276 [1] 276 💬
|
| 263 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 264 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR2 [1] FGFR2 💬
|
Palifermin Palifermin 💬
| Palifermin | 013 [5] 13, 36, 38, 39, 65 💬
|
| 265 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 266 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 267 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 268 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [1] JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 084 [1] 84 💬
|
| 269 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [1] JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬
|
| 270 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [1] JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 [4] 46, 51, 97, 228 💬
|
| 271 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [1] JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
|
| 272 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 273 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 [3] 60, 65, 228 💬
|
| 274 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 [1] 46 💬
|
| 275 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 276 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
| 277 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
| 278 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
| 279 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
| 280 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 281 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
| 282 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
| 283 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 284 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 285 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 286 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
| 287 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
| 288 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
CASP9 [1] CASP9 💬
|
Rimiducid Rimiducid 💬
| Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬
|
| 289 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
| 290 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
| 291 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 292 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 293 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 294 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Aceclofenac Aceclofenac 💬
| Aceclofenac | 046 [1] 46 💬
|
| 295 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
| 296 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Aspirin Aspirin 💬
| Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
|
| 297 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 298 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
| 299 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Diflunisal Diflunisal 💬
| Diflunisal | 028 [1] 28 💬
|
| 300 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Etodolac Etodolac 💬
| Etodolac | 046 [1] 46 💬
|
| 301 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Etoricoxib Etoricoxib 💬
| Etoricoxib | 046 [2] 46, 271 💬
|
| 302 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Flurbiprofen Flurbiprofen 💬
| Flurbiprofen | 013 [3] 13, 21, 46 💬
|
| 303 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Ibuprofen Ibuprofen 💬
| Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬
|
| 304 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Indomethacin Indomethacin 💬
| Indomethacin | 225 [3] 225, 271, 298 💬
|
| 305 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Ketoprofen Ketoprofen 💬
| Ketoprofen | 046 [1] 46 💬
|
| 306 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Ketorolac Ketorolac 💬
| Ketorolac | 070 [2] 70, 226 💬
|
| 307 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Loxoprofen Loxoprofen 💬
| Loxoprofen | 046 [2] 46, 271 💬
|
| 308 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Lumiracoxib Lumiracoxib 💬
| Lumiracoxib | 046 [1] 46 💬
|
| 309 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Meloxicam Meloxicam 💬
| Meloxicam | 046 [4] 46, 49, 271, 296 💬
|
| 310 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Naproxen Naproxen 💬
| Naproxen | 013 [4] 13, 46, 107, 271 💬
|
| 311 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Nimesulide Nimesulide 💬
| Nimesulide | 046 [1] 46 💬
|
| 312 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Parecoxib Parecoxib 💬
| Parecoxib | 046 [2] 46, 271 💬
|
| 313 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Rofecoxib Rofecoxib 💬
| Rofecoxib | 046 [1] 46 💬
|
| 314 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Salsalate Salsalate 💬
| Salsalate | 005 [1] 5 💬
|
| 315 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Sulindac Sulindac 💬
| Sulindac | 206 [1] 206 💬
|
| 316 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Tolfenamic acid Tolfenamic acid 💬
| Tolfenamic acid | 005 [1] 5 💬
|
| 317 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Valdecoxib Valdecoxib 💬
| Valdecoxib | 046 [1] 46 💬
|
| 318 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [1] RARB 💬
|
Fenretinide Fenretinide 💬
| Fenretinide | 299 [1] 299 💬
|
| 319 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [1] RARB 💬
|
Isotretinoin Isotretinoin 💬
| Isotretinoin | 036 [4] 36, 39, 159, 160 💬
|
| 320 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [1] RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 321 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [1] RARB 💬
|
Vitamin A Vitamin A 💬
| Vitamin A | 013 [3] 13, 53, 90 💬
|
| 322 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬
|
Acitretin Acitretin 💬
| Acitretin | 037 [1] 37 💬
|
| 323 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬
|
Alitretinoin Alitretinoin 💬
| Alitretinoin | 049 [1] 49 💬
|
| 324 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
| 325 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬
|
Bexarotene Bexarotene 💬
| Bexarotene | 013 [2] 13, 75 💬
|
| 326 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GBA1 [1] GBA1 💬
|
Alglucerase Alglucerase 💬
| Alglucerase | 019 [1] 19 💬
|
| 327 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GBA1 [1] GBA1 💬
|
Imiglucerase Imiglucerase 💬
| Imiglucerase | 019 [1] 19 💬
|
| 328 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GBA1 [1] GBA1 💬
|
Taliglucerase alfa Taliglucerase alfa 💬
| Taliglucerase alfa | 019 [1] 19 💬
|
| 329 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GBA1 [1] GBA1 💬
|
Velaglucerase alfa Velaglucerase alfa 💬
| Velaglucerase alfa | 019 [1] 19 💬
|
| 330 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GLA [1] GLA 💬
|
Agalsidase alfa Agalsidase alfa 💬
| Agalsidase alfa | 019 [1] 19 💬
|
| 331 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
GLA [1] GLA 💬
|
Agalsidase beta Agalsidase beta 💬
| Agalsidase beta | 019 [1] 19 💬
|
| 332 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
SMPD1 [1] SMPD1 💬
|
Olipudase alfa Olipudase alfa 💬
| Olipudase alfa | 019 [1] 19 💬
|
| 333 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
UGCG [1] UGCG 💬
|
Eliglustat Eliglustat 💬
| Eliglustat | 019 [1] 19 💬
|
| 334 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
UGCG [1] UGCG 💬
|
Lucerastat Lucerastat 💬
| Lucerastat | 019 [1] 19 💬
|
| 335 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
UGCG [1] UGCG 💬
|
Miglustat Miglustat 💬
| Miglustat | 019 [3] 19, 256, 299 💬
|
| 336 | Sphingolipid metabolism 💬 4 genes, 11 drugs (DrugBank) and 5 diseases |
UGCG [1] UGCG 💬
|
Venglustat Venglustat 💬
| Venglustat | 006 [3] 6 , 19, 67 💬
|
| 337 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 338 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 339 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 340 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 341 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 342 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [2] ADORA1, ADORA3 💬
|
Adenosine Adenosine 💬
| Adenosine | 013 [3] 13, 58, 65 💬
|
| 343 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [2] ADORA1, ADORA3 💬
|
Adenosine phosphate Adenosine phosphate 💬
| Adenosine phosphate | 046 [1] 46 💬
|
| 344 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA3 [1] ADORA3 💬
|
Piclidenoson Piclidenoson 💬
| Piclidenoson | 046 [1] 46 💬
|
| 345 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
| 346 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FCER1A [1] FCER1A 💬
|
Omalizumab Omalizumab 💬
| Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬
|
| 347 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 348 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 349 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
| 350 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
| 351 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
| 352 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
| 353 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 354 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP3K5 [1] MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 [1] 86 💬
|
| 355 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
| 356 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
| 357 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
| 358 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Loperamide Loperamide 💬
| Loperamide | 013 [2] 13, 97 💬
|
| 359 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 360 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Nalmefene Nalmefene 💬
| Nalmefene | 006 [1] 6 💬
|
| 361 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Naloxone Naloxone 💬
| Naloxone | 006 [2] 6 , 226 💬
|
| 362 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
| 363 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Oxycodone Oxycodone 💬
| Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬
|
| 364 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 365 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 366 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 367 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
| 368 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
PRKCE [1] PRKCE 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 [1] 97 💬
|
| 369 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
| 370 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
| 371 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 372 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 373 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [1] S1PR1 💬
|
Cenerimod Cenerimod 💬
| Cenerimod | 049 [1] 49 💬
|
| 374 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [1] S1PR1 💬
|
Fingolimod Fingolimod 💬
| Fingolimod | 013 [3] 13, 14, 156 💬
|
| 375 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [1] S1PR1 💬
|
Ponesimod Ponesimod 💬
| Ponesimod | 013 [1] 13 💬
|
| 376 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Amiselimod Amiselimod 💬
| Amiselimod | 097 [1] 97 💬
|
| 377 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Etrasimod Etrasimod 💬
| Etrasimod | 096 [3] 96, 97, 98 💬
|
| 378 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Ozanimod Ozanimod 💬
| Ozanimod | 013 [3] 13, 96, 97 💬
|
| 379 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [2] S1PR1, S1PR5 💬
|
Siponimod Siponimod 💬
| Siponimod | 013 [2] 13, 50 💬
|
| 380 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
SMPD1 [1] SMPD1 💬
|
Olipudase alfa Olipudase alfa 💬
| Olipudase alfa | 019 [1] 19 💬
|
| 381 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
| 382 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
| 383 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 384 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 385 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 386 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 387 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
| 388 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
| 389 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 390 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 391 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 392 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 393 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 394 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬
|
| 395 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 396 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Acamprosate Acamprosate 💬
| Acamprosate | 006 [2] 6 , 206 💬
|
| 397 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
| 398 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 399 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 400 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 401 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
| 402 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 403 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCNC3 [2] KCNC3, KCND3 💬
|
Amifampridine Amifampridine 💬
| Amifampridine | 003 [3] 3 , 11, 12 💬
|
| 404 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCNC3 [2] KCNC3, KCND3 💬
|
Dalfampridine Dalfampridine 💬
| Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬
|
| 405 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCND3 [1] KCND3 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 [2] 28, 127 💬
|
| 406 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MAP3K5 [1] MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 [1] 86 💬
|
| 407 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
| 408 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 409 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 [1] 13 💬
|
| 410 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
| 411 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
| 412 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
| 413 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
| 414 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PSMB5 [1] PSMB5 💬
|
Bortezomib Bortezomib 💬
| Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
|
| 415 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PSMB5 [1] PSMB5 💬
|
Carfilzomib Carfilzomib 💬
| Carfilzomib | 028 [1] 28 💬
|
| 416 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PSMB5 [1] PSMB5 💬
|
Ixazomib Ixazomib 💬
| Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬
|
| 417 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C1R [2] C1R, C1S 💬
|
Conestat alfa Conestat alfa 💬
| Conestat alfa | 061 [1] 61 💬
|
| 418 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C1S [1] C1S 💬
|
Sutimlimab Sutimlimab 💬
| Sutimlimab | 061 [1] 61 💬
|
| 419 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 420 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Crovalimab Crovalimab 💬
| Crovalimab | 062 [2] 62, 109 💬
|
| 421 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Eculizumab Eculizumab 💬
| Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬
|
| 422 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Nomacopan Nomacopan 💬
| Nomacopan | 062 [3] 62, 109, 162 💬
|
| 423 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Pozelimab Pozelimab 💬
| Pozelimab | 011 [2] 11, 62 💬
|
| 424 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 425 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Vilobelimab Vilobelimab 💬
| Vilobelimab | 043 [3] 43, 44, 269 💬
|
| 426 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 427 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5AR1 [1] C5AR1 💬
|
Avacopan Avacopan 💬
| Avacopan | 043 [3] 43, 44, 222 💬
|
| 428 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
CFB [1] CFB 💬
|
Iptacopan Iptacopan 💬
| Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬
|
| 429 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
CFD [1] CFD 💬
|
Danicopan Danicopan 💬
| Danicopan | 062 [1] 62 💬
|
| 430 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 431 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
ITGAL [1] ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
|
| 432 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
MASP2 [1] MASP2 💬
|
Narsoplimab Narsoplimab 💬
| Narsoplimab | 064 [4] 64, 66, 109, 222 💬
|
| 433 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
PLG [1] PLG 💬
|
Aminocaproic acid Aminocaproic acid 💬
| Aminocaproic acid | 070 [1] 70 💬
|
| 434 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
PLG [1] PLG 💬
|
Tranexamic acid Tranexamic acid 💬
| Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬
|
| 435 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
PTAFR [1] PTAFR 💬
|
Rupatadine Rupatadine 💬
| Rupatadine | 046 [1] 46 💬
|
| 436 | Starch and sucrose metabolism 💬 5 genes, 5 drugs (DrugBank) and 2 diseases |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬
|
Acarbose Acarbose 💬
| Acarbose | 298 [1] 298 💬
|
| 437 | Starch and sucrose metabolism 💬 5 genes, 5 drugs (DrugBank) and 2 diseases |
GAA [1] GAA 💬
|
Alglucosidase alfa Alglucosidase alfa 💬
| Alglucosidase alfa | 256 [1] 256 💬
|
| 438 | Starch and sucrose metabolism 💬 5 genes, 5 drugs (DrugBank) and 2 diseases |
GAA [1] GAA 💬
|
Avalglucosidase alfa Avalglucosidase alfa 💬
| Avalglucosidase alfa | 256 [1] 256 💬
|
| 439 | Starch and sucrose metabolism 💬 5 genes, 5 drugs (DrugBank) and 2 diseases |
GAA [1] GAA 💬
|
Cipaglucosidase alfa Cipaglucosidase alfa 💬
| Cipaglucosidase alfa | 256 [1] 256 💬
|
| 440 | Starch and sucrose metabolism 💬 5 genes, 5 drugs (DrugBank) and 2 diseases |
GAA [1] GAA 💬
|
Duvoglustat Duvoglustat 💬
| Duvoglustat | 256 [1] 256 💬
|
| 441 | Steroid biosynthesis 💬 1 gene, 1 drug (DrugBank) and 1 disease |
LIPA [1] LIPA 💬
|
Sebelipase alfa Sebelipase alfa 💬
| Sebelipase alfa | 019 [1] 19 💬
|
| 442 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
COMT [1] COMT 💬
|
Entacapone Entacapone 💬
| Entacapone | 006 [2] 6 , 17 💬
|
| 443 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
COMT [1] COMT 💬
|
Opicapone Opicapone 💬
| Opicapone | 006 [1] 6 💬
|
| 444 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
COMT [1] COMT 💬
|
Tolcapone Tolcapone 💬
| Tolcapone | 006 [3] 6 , 28, 127 💬
|
| 445 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP11A1 [3] CYP11A1, CYP11B1, CYP17A1 💬
|
Levoketoconazole Levoketoconazole 💬
| Levoketoconazole | 075 [1] 75 💬
|
| 446 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP11B1 [1] CYP11B1 💬
|
Metyrapone Metyrapone 💬
| Metyrapone | 075 [1] 75 💬
|
| 447 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP11B2 [1] CYP11B2 💬
|
Osilodrostat Osilodrostat 💬
| Osilodrostat | 075 [1] 75 💬
|
| 448 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
| 449 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP19A1 [1] CYP19A1 💬
|
Anastrozole Anastrozole 💬
| Anastrozole | 078 [3] 78, 86, 193 💬
|
| 450 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP19A1 [1] CYP19A1 💬
|
Letrozole Letrozole 💬
| Letrozole | 081 [2] 81, 89 💬
|
| 451 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬
|
Dutasteride Dutasteride 💬
| Dutasteride | 001 [2] 1 , 2 💬
|
| 452 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
SRD5A2 [1] SRD5A2 💬
|
Finasteride Finasteride 💬
| Finasteride | 006 [1] 6 💬
|
| 453 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
CACNA1B [1] CACNA1B 💬
|
Cilnidipine Cilnidipine 💬
| Cilnidipine | 067 [1] 67 💬
|
| 454 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
| 455 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
| 456 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
| 457 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A1 [1] SLC6A1 💬
|
Gabapentin Gabapentin 💬
| Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬
|
| 458 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [1] SLC6A2 💬
|
Atomoxetine Atomoxetine 💬
| Atomoxetine | 006 [4] 6 , 8 , 13, 17 💬
|
| 459 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
| 460 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Lisdexamfetamine Lisdexamfetamine 💬
| Lisdexamfetamine | 013 [1] 13 💬
|
| 461 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
| 462 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [3] SLC6A2, SLC6A3, SLC6A4 💬
|
Phentermine Phentermine 💬
| Phentermine | 097 [1] 97 💬
|
| 463 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Amitriptyline Amitriptyline 💬
| Amitriptyline | 078 [4] 78, 97, 226, 299 💬
|
| 464 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Amoxapine Amoxapine 💬
| Amoxapine | 046 [1] 46 💬
|
| 465 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Ampreloxetine Ampreloxetine 💬
| Ampreloxetine | 006 [2] 6 , 17 💬
|
| 466 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Desipramine Desipramine 💬
| Desipramine | 120 [2] 120, 156 💬
|
| 467 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Doxepin Doxepin 💬
| Doxepin | 006 [1] 6 💬
|
| 468 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Duloxetine Duloxetine 💬
| Duloxetine | 006 [2] 6 , 13 💬
|
| 469 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Milnacipran Milnacipran 💬
| Milnacipran | 046 [2] 46, 49 💬
|
| 470 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Nortriptyline Nortriptyline 💬
| Nortriptyline | 006 [2] 6 , 226 💬
|
| 471 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A4 💬
|
Venlafaxine Venlafaxine 💬
| Venlafaxine | 006 [3] 6 , 13, 46 💬
|
| 472 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A3 [1] SLC6A3 💬
|
Armodafinil Armodafinil 💬
| Armodafinil | 006 [3] 6 , 13, 84 💬
|
| 473 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬
|
| 474 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Escitalopram Escitalopram 💬
| Escitalopram | 002 [4] 2 , 6 , 13, 46 💬
|
| 475 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Fenfluramine Fenfluramine 💬
| Fenfluramine | 140 [4] 140, 144, 145, 149 💬
|
| 476 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Fluoxetine Fluoxetine 💬
| Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
|
| 477 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
| 478 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Sertraline Sertraline 💬
| Sertraline | 006 [2] 6 , 206 💬
|
| 479 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 480 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Vortioxetine Vortioxetine 💬
| Vortioxetine | 006 [1] 6 💬
|
| 481 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SNAP25 [1] SNAP25 💬
|
Botulinum toxin type A Botulinum toxin type A 💬
| Botulinum toxin type A | 002 [14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
|
| 482 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SNAP25 [1] SNAP25 💬
|
Rimabotulinumtoxin B Rimabotulinumtoxin B 💬
| Botulinum toxin type B | 002 [4] 2 , 6 , 13, 51 💬
|
| 483 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C1R [2] C1R, C1S 💬
|
Conestat alfa Conestat alfa 💬
| Conestat alfa | 061 [1] 61 💬
|
| 484 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C1S [1] C1S 💬
|
Sutimlimab Sutimlimab 💬
| Sutimlimab | 061 [1] 61 💬
|
| 485 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 486 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Crovalimab Crovalimab 💬
| Crovalimab | 062 [2] 62, 109 💬
|
| 487 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Eculizumab Eculizumab 💬
| Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬
|
| 488 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Nomacopan Nomacopan 💬
| Nomacopan | 062 [3] 62, 109, 162 💬
|
| 489 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Pozelimab Pozelimab 💬
| Pozelimab | 011 [2] 11, 62 💬
|
| 490 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 491 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Vilobelimab Vilobelimab 💬
| Vilobelimab | 043 [3] 43, 44, 269 💬
|
| 492 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 493 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD40 [1] CD40 💬
|
Bleselumab Bleselumab 💬
| Bleselumab | 222 [1] 222 💬
|
| 494 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD40 [1] CD40 💬
|
Iscalimab Iscalimab 💬
| Iscalimab | 049 [2] 49, 53 💬
|
| 495 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD40 [1] CD40 💬
|
Ravagalimab Ravagalimab 💬
| Ravagalimab | 053 [2] 53, 97 💬
|
| 496 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD40LG [1] CD40LG 💬
|
Toralizumab Toralizumab 💬
| Toralizumab | 063 [1] 63 💬
|
| 497 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD80 [2] CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 498 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD80 [2] CD80, CD86 💬
|
Belatacept Belatacept 💬
| Belatacept | 046 [1] 46 💬
|
| 499 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
| 500 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Acamprosate Acamprosate 💬
| Acamprosate | 006 [2] 6 , 206 💬
|
| 501 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
| 502 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 503 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 504 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 505 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
| 506 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 507 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 508 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IFNG [1] IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 [3] 49, 65, 107 💬
|
| 509 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IFNG [1] IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 [1] 46 💬
|
| 510 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 511 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
| 512 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
| 513 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 514 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 515 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 516 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 517 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
| 518 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
| 519 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 520 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|