Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
2 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
3 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
4 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
5 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
6 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
7 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
8 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
9 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
10 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
11 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
12 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
13 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
14 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
15 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
16 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
17 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
18 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
19 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
20 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
21 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
22 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
23 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
24 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
25 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
26 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
27 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
28 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
29 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
30 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
31 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
32 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
33 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
34 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
35 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
36 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
37 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
38 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
39 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
40 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
41 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
AMY2A [2] AMY2A, AMY2B 💬 |
Acarbose Acarbose 💬 |
Acarbose | 298 [1] 298 💬 💬 |
42 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
43 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
44 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CA2 [1] CA2 💬 |
Acetazolamide Acetazolamide 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬 |
45 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CA2 [1] CA2 💬 |
Dichlorphenamide Dichlorphenamide 💬 |
Diclofenamide | 114 [1] 114 💬 💬 |
46 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CA2 [1] CA2 💬 |
Dorzolamide Dorzolamide 💬 |
Dorzolamide | 090 [1] 90 💬 💬 |
47 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
48 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CD38 [1] CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬 💬 |
49 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CD38 [1] CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 [3] 28, 61, 283 💬 💬 |
50 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CD38 [1] CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 [2] 63, 66 💬 💬 |
51 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Deutivacaftor Deutivacaftor 💬 |
Deutivacaftor | 299 [1] 299 💬 💬 |
52 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Elexacaftor Elexacaftor 💬 |
Elexacaftor | 299 [1] 299 💬 💬 |
53 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Galicaftor Galicaftor 💬 |
Galicaftor | 299 [1] 299 💬 💬 |
54 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Ivacaftor Ivacaftor 💬 |
Ivacaftor | 299 [1] 299 💬 💬 |
55 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Lumacaftor Lumacaftor 💬 |
Lumacaftor | 299 [1] 299 💬 💬 |
56 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CFTR [1] CFTR 💬 |
Tezacaftor Tezacaftor 💬 |
Tezacaftor | 299 [1] 299 💬 💬 |
57 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
58 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
59 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Cevimeline Cevimeline 💬 |
Cevimeline | 053 [1] 53 💬 💬 |
60 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
61 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Darifenacin Darifenacin 💬 |
Darifenacin | 006 [2] 6 , 13 💬 💬 |
62 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
63 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
64 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
65 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
66 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
67 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Solifenacin Solifenacin 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 💬 |
68 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Tolterodine Tolterodine 💬 |
Tolterodine | 017 [2] 17, 53 💬 💬 |
69 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
70 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
71 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
KCNQ1 [1] KCNQ1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
72 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
KCNQ1 [1] KCNQ1 💬 |
Ezogabine Ezogabine 💬 |
Ezogabine | 002 [2] 2 , 144 💬 💬 |
73 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
74 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
SLC12A2 [1] SLC12A2 💬 |
Bumetanide Bumetanide 💬 |
Bumetanide | 006 [2] 6 , 158 💬 💬 |
75 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
SLC12A2 [1] SLC12A2 💬 |
Furosemide Furosemide 💬 |
Furosemide | 006 [2] 6 , 86 💬 💬 |
76 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
77 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
78 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
79 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
CASR [1] CASR 💬 |
Cinacalcet Cinacalcet 💬 |
Cinacalcet | 238 [1] 238 💬 💬 |
80 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
81 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
82 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
83 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
84 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
85 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
86 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
87 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
88 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGFR1 [1] FGFR1 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
89 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGFR1 [1] FGFR1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
90 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
91 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
92 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
93 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
94 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
95 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MMP13 [1] MMP13 💬 |
Apratastat Apratastat 💬 |
Apratastat | 046 [1] 46 💬 💬 |
96 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [1] PDE4A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
97 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
98 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
99 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
100 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
101 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
102 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
103 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
104 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
105 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
106 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
107 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
108 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
109 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
110 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PTH1R [1] PTH1R 💬 |
Parathyroid hormone Parathyroid hormone 💬 |
Parathyroid hormone | 065 [4] 65, 70, 235, 326 💬 💬 |
111 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PTH1R [1] PTH1R 💬 |
Teriparatide Teriparatide 💬 |
Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬 💬 |
112 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
113 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Alitretinoin Alitretinoin 💬 |
Alitretinoin | 049 [1] 49 💬 💬 |
114 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Bexarotene Bexarotene 💬 |
Bexarotene | 013 [2] 13, 75 💬 💬 |
115 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
SOST [1] SOST 💬 |
Romosozumab Romosozumab 💬 |
Romosozumab | 274 [1] 274 💬 💬 |
116 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
TNFSF11 [1] TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
117 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Alfacalcidol Alfacalcidol 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 💬 |
118 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Calcifediol Calcifediol 💬 |
Calcifediol | 113 [2] 113, 299 💬 💬 |
119 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Calcipotriene Calcipotriene 💬 |
Calcipotriol | 036 [2] 36, 51 💬 💬 |
120 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
121 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
122 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Dihydrotachysterol Dihydrotachysterol 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 💬 |
123 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Eldecalcitol Eldecalcitol 💬 |
Eldecalcitol | 046 [1] 46 💬 💬 |
124 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 💬 |
125 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Paricalcitol Paricalcitol 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 💬 |
126 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Adenosine Adenosine 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 💬 |
127 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Adenosine phosphate Adenosine phosphate 💬 |
Adenosine phosphate | 046 [1] 46 💬 💬 |
128 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
129 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
130 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Istradefylline Istradefylline 💬 |
Istradefylline | 006 [1] 6 💬 💬 |
131 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Preladenant Preladenant 💬 |
Preladenant | 006 [1] 6 💬 💬 |
132 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
133 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Regadenoson Regadenoson 💬 |
Regadenoson | 058 [1] 58 💬 💬 |
134 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬 |
Tozadenant Tozadenant 💬 |
Tozadenant | 006 [1] 6 💬 💬 |
135 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
136 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [1] DRD1 💬 |
Tavapadon Tavapadon 💬 |
Tavapadon | 006 [1] 6 💬 💬 |
137 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Apomorphine Apomorphine 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 💬 |
138 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Dexpramipexole Dexpramipexole 💬 |
Dexpramipexole | 002 [1] 2 💬 💬 |
139 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Dopamine Dopamine 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 💬 |
140 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Flupentixol Flupentixol 💬 |
Flupentixol | 097 [1] 97 💬 💬 |
141 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Foslevodopa Foslevodopa 💬 |
Foslevodopa | 006 [1] 6 💬 💬 |
142 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
143 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Pergolide Pergolide 💬 |
Pergolide | 006 [1] 6 💬 💬 |
144 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Aripiprazole Aripiprazole 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 💬 |
145 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
146 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Buspirone Buspirone 💬 |
Buspirone | 006 [2] 6 , 51 💬 💬 |
147 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
148 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Cariprazine Cariprazine 💬 |
Cariprazine | 021 [1] 21 💬 💬 |
149 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
150 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Domperidone Domperidone 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
151 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Domperidone maleate Domperidone maleate 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 💬 |
152 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Haloperidol Haloperidol 💬 |
Haloperidol | 008 [1] 8 💬 💬 |
153 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Iloperidone Iloperidone 💬 |
Iloperidone | 006 [1] 6 💬 💬 |
154 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Lisuride Lisuride 💬 |
Lisuride | 006 [2] 6 , 86 💬 💬 |
155 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Melperone Melperone 💬 |
Melperone | 006 [1] 6 💬 💬 |
156 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Metoclopramide Metoclopramide 💬 |
Metoclopramide | 046 [2] 46, 51 💬 💬 |
157 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Olanzapine Olanzapine 💬 |
Olanzapine | 002 [2] 2 , 8 💬 💬 |
158 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Pardoprunox Pardoprunox 💬 |
Pardoprunox | 006 [1] 6 💬 💬 |
159 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Pimozide Pimozide 💬 |
Pimozide | 002 [1] 2 💬 💬 |
160 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Piribedil Piribedil 💬 |
Piribedil | 006 [1] 6 💬 💬 |
161 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Pramipexole Pramipexole 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 💬 |
162 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Pridopidine Pridopidine 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 💬 |
163 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Quetiapine Quetiapine 💬 |
Quetiapine | 006 [2] 6 , 13 💬 💬 |
164 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Risperidone Risperidone 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 💬 |
165 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Ropinirole Ropinirole 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 💬 |
166 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Rotigotine Rotigotine 💬 |
Rotigotine | 006 [1] 6 💬 💬 |
167 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Sulpiride Sulpiride 💬 |
Sulpiride | 006 [2] 6 , 70 💬 💬 |
168 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
169 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Tiapride Tiapride 💬 |
Tiapride | 008 [1] 8 💬 💬 |
170 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
171 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 💬 |
172 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
KEAP1 [1] KEAP1 💬 |
Dimethyl fumarate Dimethyl fumarate 💬 |
Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬 💬 |
173 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOA [1] MAOA 💬 |
Moclobemide Moclobemide 💬 |
Moclobemide | 006 [1] 6 💬 💬 |
174 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOA [2] MAOA, MAOB 💬 |
Iproniazid Iproniazid 💬 |
Iproniazid | 006 [1] 6 💬 💬 |
175 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phenelzine Phenelzine 💬 |
Phenelzine | 006 [1] 6 💬 💬 |
176 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
177 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬 |
Rasagiline Rasagiline 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
178 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬 |
Rasagiline tartrate Rasagiline tartrate 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
179 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬 |
Safinamide Safinamide 💬 |
Safinamide | 006 [2] 6 , 17 💬 💬 |
180 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬 |
Selegiline Selegiline 💬 |
Selegiline | 006 [1] 6 💬 💬 |
181 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
182 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAPT [1] MAPT 💬 |
Flortaucipir F 18 Flortaucipir F 18 💬 |
Flortaucipir | 005 [3] 5 , 7 , 127 💬 💬 |
183 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAPT [1] MAPT 💬 |
Gosuranemab Gosuranemab 💬 |
Gosuranemab | 005 [1] 5 💬 💬 |
184 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAPT [1] MAPT 💬 |
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬 |
Hydromethylthionine mesylate | 127 [1] 127 💬 💬 |
185 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
NFE2L2 [1] NFE2L2 💬 |
Omaveloxolone Omaveloxolone 💬 |
Omaveloxolone | 018 [1] 18 💬 💬 |
186 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
187 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
PSMB5 [1] PSMB5 💬 |
Carfilzomib Carfilzomib 💬 |
Carfilzomib | 028 [1] 28 💬 💬 |
188 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
PSMB5 [1] PSMB5 💬 |
Ixazomib Ixazomib 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 💬 |
189 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬 |
Deutetrabenazine Deutetrabenazine 💬 |
Deutetrabenazine | 008 [1] 8 💬 💬 |
190 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬 |
Tetrabenazine Tetrabenazine 💬 |
Tetrabenazine | 008 [1] 8 💬 💬 |
191 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬 |
Valbenazine Valbenazine 💬 |
Valbenazine | 008 [1] 8 💬 💬 |
192 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 💬 |
193 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬 |
Bupropion Bupropion 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 💬 |
194 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬 |
Lisdexamfetamine Lisdexamfetamine 💬 |
Lisdexamfetamine | 013 [1] 13 💬 💬 |
195 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
196 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SNCA [1] SNCA 💬 |
Prasinezumab Prasinezumab 💬 |
Prasinezumab | 006 [1] 6 💬 💬 |
197 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |
198 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
199 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
200 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
201 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 [2] 46, 85 💬 💬 |
202 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 [2] 34, 65 💬 💬 |
203 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 💬 |
204 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
205 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
206 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
207 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
208 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [2] ABL1, SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
209 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
210 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
211 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
212 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
213 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
214 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
215 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
216 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
217 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
218 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
219 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
220 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
221 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
222 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
223 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
224 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
225 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
226 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
227 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
228 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
229 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
230 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
231 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
232 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
233 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
234 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
235 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
236 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
237 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
238 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
239 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
240 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
241 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 [2] 46, 85 💬 💬 |
242 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 [2] 34, 65 💬 💬 |
243 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 💬 |
244 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [1] ABL1 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
245 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
246 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
247 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
248 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
249 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
250 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
251 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
252 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
253 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
254 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
255 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
256 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
257 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
258 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [2] AGTR1, EDNRA 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
259 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ALK [1] ALK 💬 |
Brigatinib Brigatinib 💬 |
Brigatinib | 034 [1] 34 💬 💬 |
260 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ALK [1] ALK 💬 |
Crizotinib Crizotinib 💬 |
Crizotinib | 034 [1] 34 💬 💬 |
261 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Calusterone Calusterone 💬 |
Calusterone | 002 [1] 2 💬 💬 |
262 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Flutamide Flutamide 💬 |
Flutamide | 081 [1] 81 💬 💬 |
263 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Nandrolone Nandrolone 💬 |
Nandrolone | 060 [2] 60, 85 💬 💬 |
264 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Nandrolone decanoate Nandrolone decanoate 💬 |
Nandrolone decanoate | 060 [2] 60, 85 💬 💬 |
265 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
266 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Stanozolol Stanozolol 💬 |
Stanozolol | 060 [1] 60 💬 💬 |
267 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
268 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone decanoate Testosterone decanoate 💬 |
Testosterone decanoate | 113 [1] 113 💬 💬 |
269 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone enanthate Testosterone enanthate 💬 |
Testosterone enanthate | 113 [1] 113 💬 💬 |
270 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone phenylpropionate Testosterone phenylpropionate 💬 |
Testosterone phenylpropionate | 113 [1] 113 💬 💬 |
271 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone propionate Testosterone propionate 💬 |
Testosterone propionate | 113 [1] 113 💬 💬 |
272 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone undecanoate Testosterone undecanoate 💬 |
Testosterone undecanoate | 013 [2] 13, 60 💬 💬 |
273 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [2] AR, ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
274 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [3] AR, ESR1, ESR2 💬 |
Prasterone Prasterone 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 💬 |
275 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
276 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
277 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
278 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
279 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
280 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF1R [7] CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
281 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
282 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF2RA [1] CSF2RA 💬 |
Mavrilimumab Mavrilimumab 💬 |
Mavrilimumab | 041 [2] 41, 46 💬 💬 |
283 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF2RA [1] CSF2RA 💬 |
Molgramostim Molgramostim 💬 |
Molgramostim | 097 [3] 97, 229, 299 💬 💬 |
284 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF2RA [1] CSF2RA 💬 |
Regramostim Regramostim 💬 |
Regramostim | 229 [1] 229 💬 💬 |
285 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF2RA [1] CSF2RA 💬 |
Sargramostim Sargramostim 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 💬 |
286 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
287 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
288 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬 |
Pegfilgrastim Pegfilgrastim 💬 |
Pegfilgrastim | 060 [1] 60 💬 💬 |
289 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CXCR4 [1] CXCR4 💬 |
Plerixafor Plerixafor 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 💬 |
290 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
291 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬 |
Sitaxentan Sitaxentan 💬 |
Sitaxentan | 086 [1] 86 💬 💬 |
292 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬 |
Zibotentan Zibotentan 💬 |
Zibotentan | 051 [1] 51 💬 💬 |
293 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
294 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
295 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Macitentan Macitentan 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 💬 |
296 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
297 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
298 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
299 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
300 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
301 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
302 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [3] EGFR, ERBB2, FLT4 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
303 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EPOR [1] EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 [1] 283 💬 💬 |
304 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [1] ESR1 💬 |
Desogestrel Desogestrel 💬 |
Desogestrel | 230 [1] 230 💬 💬 |
305 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [1] ESR1 💬 |
Ethinyl estradiol Ethinyl estradiol 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 💬 |
306 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Clomifene Clomifene 💬 |
Clomifene | 074 [1] 74 💬 💬 |
307 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
308 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
309 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol Estradiol 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 💬 |
310 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol valerate Estradiol valerate 💬 |
Estradiol valerate | 065 [1] 65 💬 💬 |
311 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol Estriol 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
312 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol tripropionate Estriol tripropionate 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
313 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Fulvestrant Fulvestrant 💬 |
Fulvestrant | 049 [2] 49, 86 💬 💬 |
314 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Mestranol Mestranol 💬 |
Mestranol | 046 [2] 46, 49 💬 💬 |
315 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Raloxifene Raloxifene 💬 |
Raloxifene | 046 [1] 46 💬 💬 |
316 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Tamoxifen Tamoxifen 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 💬 |
317 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
318 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
319 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
320 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
321 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
322 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR1 [6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
323 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
324 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FLT4 [1] FLT4 💬 |
Axitinib Axitinib 💬 |
Axitinib | 034 [1] 34 💬 💬 |
325 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FLT4 [1] FLT4 💬 |
Cediranib Cediranib 💬 |
Cediranib | 034 [1] 34 💬 💬 |
326 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 [2] 75, 96 💬 💬 |
327 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
HMOX1 [1] HMOX1 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
328 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
329 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
330 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 💬 |
331 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 💬 |
332 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 [1] 56 💬 💬 |
333 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 💬 |
334 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 💬 |
335 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 [1] 13 💬 💬 |
336 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 💬 |
337 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
338 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
339 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
Interferon gamma-1b Interferon gamma-1b 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 💬 |
340 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
341 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
342 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
343 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
344 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬 |
Anrukinzumab Anrukinzumab 💬 |
Anrukinzumab | 097 [1] 97 💬 💬 |
345 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬 |
Lebrikizumab Lebrikizumab 💬 |
Lebrikizumab | 085 [1] 85 💬 💬 |
346 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬 |
Tralokinumab Tralokinumab 💬 |
Tralokinumab | 085 [2] 85, 97 💬 💬 |
347 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Brazikumab Brazikumab 💬 |
Brazikumab | 096 [2] 96, 97 💬 💬 |
348 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
349 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
350 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
351 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Tildrakizumab Tildrakizumab 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 💬 |
352 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [1] IL2RA 💬 |
Basiliximab Basiliximab 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 💬 |
353 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [1] IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
354 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
Aldesleukin Aldesleukin 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 💬 |
355 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL4 [1] IL4 💬 |
Binetrakin Binetrakin 💬 |
Binetrakin | 046 [1] 46 💬 💬 |
356 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL4R [1] IL4R 💬 |
Dupilumab Dupilumab 💬 |
Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬 💬 |
357 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5 [1] IL5 💬 |
Mepolizumab Mepolizumab 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 💬 |
358 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5 [1] IL5 💬 |
Reslizumab Reslizumab 💬 |
Reslizumab | 044 [2] 44, 98 💬 💬 |
359 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5RA [1] IL5RA 💬 |
Benralizumab Benralizumab 💬 |
Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬 💬 |
360 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
361 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
362 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
363 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
364 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
365 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R [1] IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 💬 |
366 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R [1] IL6R 💬 |
Satralizumab Satralizumab 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 💬 |
367 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R [1] IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
368 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
369 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
370 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
371 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
372 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
373 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
374 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
375 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
376 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
KEAP1 [1] KEAP1 💬 |
Dimethyl fumarate Dimethyl fumarate 💬 |
Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬 💬 |
377 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
378 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
379 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
380 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
381 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
382 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
383 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
384 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
385 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
386 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
387 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NFE2L2 [1] NFE2L2 💬 |
Omaveloxolone Omaveloxolone 💬 |
Omaveloxolone | 018 [1] 18 💬 💬 |
388 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
389 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NQO1 [1] NQO1 💬 |
Warfarin Warfarin 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬 |
390 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PGF [3] PGF, VEGFA, VEGFB 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
391 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
392 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
393 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
394 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PML [3] PML, RARA, RARB 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 💬 |
395 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬 |
Bocidelpar Bocidelpar 💬 |
Bocidelpar | 113 [1] 113 💬 💬 |
396 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬 |
Leriglitazone Leriglitazone 💬 |
Leriglitazone | 020 [1] 20 💬 💬 |
397 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
398 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 💬 |
399 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬 |
Seladelpar Seladelpar 💬 |
Seladelpar | 093 [2] 93, 94 💬 💬 |
400 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
401 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGER1 [1] PTGER1 💬 |
Alprostadil Alprostadil 💬 |
Alprostadil | 051 [2] 51, 70 💬 💬 |
402 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGER1 [1] PTGER1 💬 |
Limaprost Limaprost 💬 |
Limaprost | 070 [1] 70 💬 💬 |
403 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGER2 [3] PTGER2, PTGER3, PTGER4 💬 |
Misoprostol Misoprostol 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 💬 |
404 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
405 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
406 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
407 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
408 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
409 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
410 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
411 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
412 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
413 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
414 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
415 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
416 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
417 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
418 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
419 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
420 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
421 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
422 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
423 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
424 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
425 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
426 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
427 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
428 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [1] RARA 💬 |
Tamibarotene Tamibarotene 💬 |
Tamibarotene | 026 [2] 26, 96 💬 💬 |
429 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [2] RARA, RARB 💬 |
Fenretinide Fenretinide 💬 |
Fenretinide | 299 [1] 299 💬 💬 |
430 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [2] RARA, RARB 💬 |
Isotretinoin Isotretinoin 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 💬 |
431 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [2] RARA, RARB 💬 |
Vitamin A Vitamin A 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 💬 |
432 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [5] RARA, RARB, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
433 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [5] RARA, RARB, RXRA, RXRB, RXRG 💬 |
Alitretinoin Alitretinoin 💬 |
Alitretinoin | 049 [1] 49 💬 💬 |
434 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
435 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
436 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
437 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Bexarotene Bexarotene 💬 |
Bexarotene | 013 [2] 13, 75 💬 💬 |
438 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬 |
Taladegib Taladegib 💬 |
Taladegib | 085 [1] 85 💬 💬 |
439 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬 |
Vismodegib Vismodegib 💬 |
Vismodegib | 085 [1] 85 💬 💬 |
440 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
441 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
442 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
443 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
444 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
445 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
446 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
447 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
448 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
449 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
450 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
451 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
452 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
453 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
454 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
455 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
456 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
457 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
458 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
459 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
460 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
461 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
462 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
463 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
464 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [4] CHRM1, CHRM3, CHRM5, SIGMAR1 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
465 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Cevimeline Cevimeline 💬 |
Cevimeline | 053 [1] 53 💬 💬 |
466 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Darifenacin Darifenacin 💬 |
Darifenacin | 006 [2] 6 , 13 💬 💬 |
467 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
468 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
469 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Solifenacin Solifenacin 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 💬 |
470 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM3 [1] CHRM3 💬 |
Tolterodine Tolterodine 💬 |
Tolterodine | 017 [2] 17, 53 💬 💬 |
471 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRNA7 [1] CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 💬 |
472 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Perampanel Perampanel 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 💬 |
473 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Talampanel Talampanel 💬 |
Talampanel | 002 [2] 2 , 6 💬 💬 |
474 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
475 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
476 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
477 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
478 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
479 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
480 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
481 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
482 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
483 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
484 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
485 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
486 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
487 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
488 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
489 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
490 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
491 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
492 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
493 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
494 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
495 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
496 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
497 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
498 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
499 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPT [1] MAPT 💬 |
Flortaucipir F 18 Flortaucipir F 18 💬 |
Flortaucipir | 005 [3] 5 , 7 , 127 💬 💬 |
500 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPT [1] MAPT 💬 |
Gosuranemab Gosuranemab 💬 |
Gosuranemab | 005 [1] 5 💬 💬 |
501 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPT [1] MAPT 💬 |
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬 |
Hydromethylthionine mesylate | 127 [1] 127 💬 💬 |
502 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
503 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
504 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
505 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
506 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
507 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
508 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
509 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
510 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
511 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
512 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSEN1 [1] PSEN1 💬 |
Tarenflurbil Tarenflurbil 💬 |
Tarenflurbil | 013 [1] 13 💬 💬 |
513 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
514 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSMB5 [1] PSMB5 💬 |
Carfilzomib Carfilzomib 💬 |
Carfilzomib | 028 [1] 28 💬 💬 |
515 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSMB5 [1] PSMB5 💬 |
Ixazomib Ixazomib 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 💬 |
516 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
517 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
518 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
519 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
520 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
521 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
522 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
523 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
524 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
525 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
526 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
527 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
528 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
529 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
530 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
531 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
532 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
533 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
534 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
535 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
536 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
537 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
538 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
539 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
540 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
541 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SIGMAR1 [1] SIGMAR1 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
542 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 💬 |
543 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬 |
Bupropion Bupropion 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 💬 |
544 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬 |
Lisdexamfetamine Lisdexamfetamine 💬 |
Lisdexamfetamine | 013 [1] 13 💬 💬 |
545 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
546 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
547 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SNCA [1] SNCA 💬 |
Prasinezumab Prasinezumab 💬 |
Prasinezumab | 006 [1] 6 💬 💬 |
548 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |
549 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
550 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
551 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
552 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
553 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
554 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
555 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
556 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
557 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
558 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
559 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
560 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
561 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 [2] 46, 85 💬 💬 |
562 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 [2] 34, 65 💬 💬 |
563 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 💬 |
564 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
ALK [1] ALK 💬 |
Brigatinib Brigatinib 💬 |
Brigatinib | 034 [1] 34 💬 💬 |
565 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
ALK [1] ALK 💬 |
Crizotinib Crizotinib 💬 |
Crizotinib | 034 [1] 34 💬 💬 |
566 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬 |
Atezolizumab Atezolizumab 💬 |
Atezolizumab | 085 [1] 85 💬 💬 |
567 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬 |
Durvalumab Durvalumab 💬 |
Durvalumab | 085 [1] 85 💬 💬 |
568 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Otelixizumab Otelixizumab 💬 |
Otelixizumab | 046 [1] 46 💬 💬 |
569 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
Visilizumab Visilizumab 💬 |
Visilizumab | 096 [2] 96, 97 💬 💬 |
570 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD3E [1] CD3E 💬 |
Mosunetuzumab Mosunetuzumab 💬 |
Mosunetuzumab | 049 [1] 49 💬 💬 |
571 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD4 [1] CD4 💬 |
Zanolimumab Zanolimumab 💬 |
Zanolimumab | 046 [1] 46 💬 💬 |
572 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
573 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
574 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
575 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
576 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
577 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
578 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
579 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
580 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
581 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
Interferon gamma-1b Interferon gamma-1b 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 💬 |
582 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
583 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
584 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
585 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
586 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
587 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
588 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
589 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
590 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
591 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
592 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
593 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
594 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
595 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
596 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
597 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
598 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
599 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
600 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
601 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
602 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
603 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 [1] PDCD1 💬 |
Nivolumab Nivolumab 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 💬 |
604 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 [1] PDCD1 💬 |
Pembrolizumab Pembrolizumab 💬 |
Pembrolizumab | 025 [2] 25, 285 💬 💬 |
605 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
606 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
607 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
608 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
609 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
610 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
611 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
612 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
613 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PRKCQ [1] PRKCQ 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
614 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
615 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
616 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
TLR9 [1] TLR9 💬 |
Cobitolimod Cobitolimod 💬 |
Cobitolimod | 097 [1] 97 💬 💬 |
617 | Pentose and glucuronate interconversions 💬 1 gene, 1 drug (DrugBank) and 1 disease |
GUSB [1] GUSB 💬 |
Vestronidase alfa Vestronidase alfa 💬 |
Vestronidase alfa | 019 [1] 19 💬 💬 |
618 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
ABCD1 [1] ABCD1 💬 |
Elivaldogene autotemcel Elivaldogene autotemcel 💬 |
Elivaldogene autotemcel | 020 [1] 20 💬 💬 |
619 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
HAO1 [1] HAO1 💬 |
Lumasiran Lumasiran 💬 |
Lumasiran | 234 [1] 234 💬 💬 |
620 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |
621 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
622 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
XDH [1] XDH 💬 |
Febuxostat Febuxostat 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 💬 |
623 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C1R [2] C1R, C1S 💬 |
Conestat alfa Conestat alfa 💬 |
Conestat alfa | 061 [1] 61 💬 💬 |
624 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C1S [1] C1S 💬 |
Sutimlimab Sutimlimab 💬 |
Sutimlimab | 061 [1] 61 💬 💬 |
625 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C3 [1] C3 💬 |
Pegcetacoplan Pegcetacoplan 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 💬 |
626 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Crovalimab Crovalimab 💬 |
Crovalimab | 062 [2] 62, 109 💬 💬 |
627 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Eculizumab Eculizumab 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 💬 |
628 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Nomacopan Nomacopan 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 💬 |
629 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Pozelimab Pozelimab 💬 |
Pozelimab | 011 [2] 11, 62 💬 💬 |
630 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Ravulizumab Ravulizumab 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 💬 |
631 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Vilobelimab Vilobelimab 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 💬 |
632 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬 |
Zilucoplan Zilucoplan 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 💬 |
633 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
634 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
635 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
636 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
637 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
638 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
639 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Brazikumab Brazikumab 💬 |
Brazikumab | 096 [2] 96, 97 💬 💬 |
640 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
641 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
642 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
643 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Tildrakizumab Tildrakizumab 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 💬 |
644 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
645 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
646 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
647 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
648 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
649 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
650 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
651 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
652 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
653 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
654 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
655 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
656 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
657 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
658 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
659 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
660 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
661 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
C1R [1] C1R 💬 |
Conestat alfa Conestat alfa 💬 |
Conestat alfa | 061 [1] 61 💬 💬 |
662 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
C3 [1] C3 💬 |
Pegcetacoplan Pegcetacoplan 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 💬 |
663 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
MPO [1] MPO 💬 |
Verdiperstat Verdiperstat 💬 |
Verdiperstat | 002 [3] 2 , 17, 127 💬 💬 |
664 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TFRC [1] TFRC 💬 |
Pabinafusp alfa Pabinafusp alfa 💬 |
Pabinafusp alfa | 019 [1] 19 💬 💬 |
665 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
666 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
667 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
668 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 [2] 46, 85 💬 💬 |
669 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 [2] 34, 65 💬 💬 |
670 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 💬 |
671 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
AOC3 [1] AOC3 💬 |
Hydralazine Hydralazine 💬 |
Hydralazine | 067 [1] 67 💬 💬 |
672 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
DDC [1] DDC 💬 |
Benserazide Benserazide 💬 |
Benserazide | 006 [1] 6 💬 💬 |
673 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
674 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
HPD [1] HPD 💬 |
Nitisinone Nitisinone 💬 |
Nitisinone | 006 [3] 6 , 164, 241 💬 💬 |
675 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOA [1] MAOA 💬 |
Moclobemide Moclobemide 💬 |
Moclobemide | 006 [1] 6 💬 💬 |
676 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOA [2] MAOA, MAOB 💬 |
Iproniazid Iproniazid 💬 |
Iproniazid | 006 [1] 6 💬 💬 |
677 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phenelzine Phenelzine 💬 |
Phenelzine | 006 [1] 6 💬 💬 |
678 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
679 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬 |
Rasagiline Rasagiline 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
680 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬 |
Rasagiline tartrate Rasagiline tartrate 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
681 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬 |
Safinamide Safinamide 💬 |
Safinamide | 006 [2] 6 , 17 💬 💬 |
682 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬 |
Selegiline Selegiline 💬 |
Selegiline | 006 [1] 6 💬 💬 |
683 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
PAH [1] PAH 💬 |
Pegvaliase Pegvaliase 💬 |
Pegvaliase | 240 [1] 240 💬 💬 |
684 | Phenylalanine, tyrosine and tryptophan biosynthesis 💬 1 gene, 1 drug (DrugBank) and 1 disease |
PAH [1] PAH 💬 |
Pegvaliase Pegvaliase 💬 |
Pegvaliase | 240 [1] 240 💬 💬 |
685 | Phosphatidylinositol signaling system 💬 4 genes, 4 drugs (DrugBank) and 6 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
686 | Phosphatidylinositol signaling system 💬 4 genes, 4 drugs (DrugBank) and 6 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
687 | Phosphatidylinositol signaling system 💬 4 genes, 4 drugs (DrugBank) and 6 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
688 | Phosphatidylinositol signaling system 💬 4 genes, 4 drugs (DrugBank) and 6 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
689 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
690 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Angiotensin II Angiotensin II 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 💬 |
691 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan Candesartan 💬 |
Candesartan | 058 [2] 58, 67 💬 💬 |
692 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Candesartan cilexetil Candesartan cilexetil 💬 |
Candesartan cilexetil | 067 [1] 67 💬 💬 |
693 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Irbesartan Irbesartan 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 💬 |
694 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Losartan Losartan 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬 |
695 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Sparsentan Sparsentan 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 💬 |
696 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Telmisartan Telmisartan 💬 |
Telmisartan | 066 [2] 66, 67 💬 💬 |
697 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
698 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR1A [3] AVPR1A, AVPR1B, AVPR2 💬 |
Terlipressin Terlipressin 💬 |
Terlipressin | 299 [1] 299 💬 💬 |
699 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR1A [3] AVPR1A, AVPR1B, AVPR2 💬 |
Vasopressin Vasopressin 💬 |
Vasopressin | 210 [1] 210 💬 💬 |
700 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬 |
Conivaptan Conivaptan 💬 |
Conivaptan | 086 [1] 86 💬 💬 |
701 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR2 [1] AVPR2 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |
702 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR2 [1] AVPR2 💬 |
Lixivaptan Lixivaptan 💬 |
Lixivaptan | 067 [1] 67 💬 💬 |
703 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR2 [1] AVPR2 💬 |
Tolvaptan Tolvaptan 💬 |
Tolvaptan | 067 [4] 67, 72, 86, 225 💬 💬 |
704 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
CXCR1 [2] CXCR1, CXCR2 💬 |
Reparixin Reparixin 💬 |
Reparixin | 298 [2] 298, 299 💬 💬 |
705 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
706 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
707 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
708 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
709 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
710 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
711 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
712 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
713 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
714 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
715 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FCER1A [1] FCER1A 💬 |
Omalizumab Omalizumab 💬 |
Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬 💬 |
716 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
717 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
718 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
719 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
720 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
721 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
722 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [1] KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
723 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
724 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
725 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
726 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
727 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
728 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
729 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
730 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
731 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
732 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
733 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
734 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
735 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
736 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
737 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
738 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
739 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PTGFR [1] PTGFR 💬 |
Tafluprost Tafluprost 💬 |
Tafluprost | 299 [1] 299 💬 💬 |
740 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PTGFR [1] PTGFR 💬 |
Unoprostone Unoprostone 💬 |
Unoprostone | 090 [1] 90 💬 💬 |
741 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
SYK [1] SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 💬 |
742 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
743 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
744 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CD19 [1] CD19 💬 |
Inebilizumab Inebilizumab 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 💬 |
745 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CD19 [1] CD19 💬 |
Obexelimab Obexelimab 💬 |
Obexelimab | 300 [1] 300 💬 💬 |
746 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
747 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Atropine Atropine 💬 |
Atropine | 002 [2] 2 , 299 💬 💬 |
748 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 [1] 156 💬 💬 |
749 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Chlorpromazine Chlorpromazine 💬 |
Chlorpromazine | 254 [1] 254 💬 💬 |
750 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Oxybutynin Oxybutynin 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 💬 |
751 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
752 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Scopolamine Scopolamine 💬 |
Scopolamine | 002 [1] 2 💬 💬 |
753 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Trihexyphenidyl Trihexyphenidyl 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 💬 |
754 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
Tropicamide Tropicamide 💬 |
Tropicamide | 006 [1] 6 💬 💬 |
755 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM2 [1] CHRM2 💬 |
Fesoterodine Fesoterodine 💬 |
Fesoterodine | 006 [1] 6 💬 💬 |
756 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM2 [1] CHRM2 💬 |
Pilocarpine Pilocarpine 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 💬 |
757 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
758 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 [1] 34 💬 💬 |
759 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
760 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
761 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬 |
Pegfilgrastim Pegfilgrastim 💬 |
Pegfilgrastim | 060 [1] 60 💬 💬 |
762 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
763 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
764 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
765 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
766 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
767 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
768 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
769 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
770 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
771 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPOR [1] EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 [1] 283 💬 💬 |
772 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
773 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
774 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
775 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
776 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Axitinib Axitinib 💬 |
Axitinib | 034 [1] 34 💬 💬 |
777 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬 |
Cediranib Cediranib 💬 |
Cediranib | 034 [1] 34 💬 💬 |
778 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
779 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [1] GHR 💬 |
Lonapegsomatropin Lonapegsomatropin 💬 |
Lonapegsomatropin | 078 [1] 78 💬 💬 |
780 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [1] GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 [2] 78, 265 💬 💬 |
781 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [1] GHR 💬 |
Somapacitan Somapacitan 💬 |
Somapacitan | 078 [2] 78, 195 💬 💬 |
782 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [1] GHR 💬 |
Somavaratan Somavaratan 💬 |
Somavaratan | 078 [1] 78 💬 💬 |
783 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [2] GHR, IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
784 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Rontalizumab Rontalizumab 💬 |
Rontalizumab | 049 [1] 49 💬 💬 |
785 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
Sifalimumab Sifalimumab 💬 |
Sifalimumab | 049 [1] 49 💬 💬 |
786 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 💬 |
787 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 💬 |
788 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 [1] 56 💬 💬 |
789 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 💬 |
790 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 💬 |
791 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 [1] 13 💬 💬 |
792 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 💬 |
793 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
794 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
795 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [1] IL2RA 💬 |
Basiliximab Basiliximab 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 💬 |
796 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [1] IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
797 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
Aldesleukin Aldesleukin 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 💬 |
798 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL4 [1] IL4 💬 |
Binetrakin Binetrakin 💬 |
Binetrakin | 046 [1] 46 💬 💬 |
799 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL4R [1] IL4R 💬 |
Dupilumab Dupilumab 💬 |
Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬 💬 |
800 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
801 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
802 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
803 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
804 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
805 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R [1] IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 💬 |
806 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R [1] IL6R 💬 |
Satralizumab Satralizumab 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 💬 |
807 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R [1] IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
808 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
809 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
810 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
811 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGA4 [1] ITGA4 💬 |
Firategrast Firategrast 💬 |
Firategrast | 013 [1] 13 💬 💬 |
812 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGA4 [1] ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 💬 |
813 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Abrilumab Abrilumab 💬 |
Abrilumab | 096 [2] 96, 97 💬 💬 |
814 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Vedolizumab Vedolizumab 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 💬 |
815 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGB7 [1] ITGB7 💬 |
Etrolizumab Etrolizumab 💬 |
Etrolizumab | 096 [2] 96, 97 💬 💬 |
816 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [1] JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 [1] 84 💬 💬 |
817 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [1] JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 💬 |
818 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [1] JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 💬 |
819 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [1] JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
820 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
821 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [2] JAK1, JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
822 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
823 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
824 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KDR [2] KDR, MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
825 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [1] KIT 💬 |
Masitinib Masitinib 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 💬 |
826 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
827 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
828 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
829 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
830 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
831 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
832 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
833 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
834 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
835 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
836 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
837 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
NGF [1] NGF 💬 |
Tanezumab Tanezumab 💬 |
Tanezumab | 226 [2] 226, 298 💬 💬 |
838 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
NGFR [1] NGFR 💬 |
Cenegermin Cenegermin 💬 |
Cenegermin | 053 [2] 53, 90 💬 💬 |
839 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PGF [3] PGF, VEGFA, VEGFB 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
840 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
841 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
842 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
843 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
844 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRL [1] PRL 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
845 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRL [1] PRL 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
846 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRL [1] PRL 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
847 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
848 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
RXRA [1] RXRA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
849 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
RXRA [1] RXRA 💬 |
Alitretinoin Alitretinoin 💬 |
Alitretinoin | 049 [1] 49 💬 💬 |
850 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
RXRA [1] RXRA 💬 |
Bexarotene Bexarotene 💬 |
Bexarotene | 013 [2] 13, 75 💬 💬 |
851 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
SYK [1] SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 💬 |
852 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
853 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
854 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VWF [1] VWF 💬 |
Caplacizumab Caplacizumab 💬 |
Caplacizumab | 064 [1] 64 💬 💬 |
855 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Acalabrutinib Acalabrutinib 💬 |
Acalabrutinib | 046 [2] 46, 61 💬 💬 |
856 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Branebrutinib Branebrutinib 💬 |
Branebrutinib | 046 [3] 46, 49, 53 💬 💬 |
857 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Evobrutinib Evobrutinib 💬 |
Evobrutinib | 013 [3] 13, 46, 49 💬 💬 |
858 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Fenebrutinib Fenebrutinib 💬 |
Fenebrutinib | 013 [1] 13 💬 💬 |
859 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Ibrutinib Ibrutinib 💬 |
Ibrutinib | 028 [3] 28, 60, 61 💬 💬 |
860 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 [4] 13, 49, 61, 63 💬 💬 |
861 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Remibrutinib Remibrutinib 💬 |
Remibrutinib | 013 [2] 13, 53 💬 💬 |
862 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK [1] BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬 💬 |
863 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬 |
Dabigatran Dabigatran 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 💬 |
864 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬 |
Dabigatran etexilate Dabigatran etexilate 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 💬 |
865 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬 |
Thrombomodulin alfa Thrombomodulin alfa 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 💬 |
866 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
867 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
868 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
869 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
870 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
871 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
872 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬 |
Clopidogrel Clopidogrel 💬 |
Clopidogrel | 049 [3] 49, 51, 86 💬 💬 |
873 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬 |
Clopidogrel hydrochloride Clopidogrel hydrochloride 💬 |
Clopidogrel | 049 [3] 49, 51, 86 💬 💬 |
874 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬 |
Clopidogrel besilate Clopidogrel besilate 💬 |
Clopidogrel | 049 [3] 49, 51, 86 💬 💬 |
875 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬 |
Ticagrelor Ticagrelor 💬 |
Ticagrelor | 036 [3] 36, 46, 85 💬 💬 |
876 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
877 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
878 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
879 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Beraprost Beraprost 💬 |
Beraprost | 086 [1] 86 💬 💬 |
880 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Epoprostenol Epoprostenol 💬 |
Epoprostenol | 086 [1] 86 💬 💬 |
881 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
882 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Iloprost Iloprost 💬 |
Iloprost | 051 [4] 51, 84, 85, 86 💬 💬 |
883 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Ralinepag Ralinepag 💬 |
Ralinepag | 086 [1] 86 💬 💬 |
884 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Selexipag Selexipag 💬 |
Selexipag | 051 [5] 51, 70, 84, 86, 88 💬 💬 |
885 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬 |
Treprostinil Treprostinil 💬 |
Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬 💬 |
886 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
887 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
888 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
889 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
890 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
891 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
892 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
893 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
894 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
895 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
896 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
897 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
898 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
899 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
900 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
901 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
902 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
903 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
904 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
SYK [1] SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 💬 |
905 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
TBXA2R [1] TBXA2R 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
906 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
TBXA2R [1] TBXA2R 💬 |
Ifetroban Ifetroban 💬 |
Ifetroban | 085 [2] 85, 113 💬 💬 |
907 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
TBXA2R [1] TBXA2R 💬 |
Ramatroban Ramatroban 💬 |
Ramatroban | 013 [1] 13 💬 💬 |
908 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
VWF [1] VWF 💬 |
Caplacizumab Caplacizumab 💬 |
Caplacizumab | 064 [1] 64 💬 💬 |
909 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
910 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
911 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
912 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
913 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
914 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
915 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
916 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
917 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
918 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Daunorubicin Daunorubicin 💬 |
Daunorubicin | 065 [1] 65 💬 💬 |
919 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Dexrazoxane Dexrazoxane 💬 |
Dexrazoxane | 013 [1] 13 💬 💬 |
920 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Doxorubicin Doxorubicin 💬 |
Doxorubicin | 026 [5] 26, 28, 34, 65, 331 💬 💬 |
921 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Etoposide Etoposide 💬 |
Etoposide | 011 [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬 💬 |
922 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Mitoxantrone Mitoxantrone 💬 |
Mitoxantrone | 013 [1] 13 💬 💬 |
923 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬 |
Pixantrone Pixantrone 💬 |
Pixantrone | 011 [2] 11, 13 💬 💬 |
924 | Porphyrin metabolism 💬 5 genes, 4 drugs (DrugBank) and 2 diseases |
ALAS1 [1] ALAS1 💬 |
Givosiran Givosiran 💬 |
Givosiran | 254 [1] 254 💬 💬 |
925 | Porphyrin metabolism 💬 5 genes, 4 drugs (DrugBank) and 2 diseases |
ALAS1 [2] ALAS1, ALAS2 💬 |
Hemin Hemin 💬 |
Hemin | 254 [1] 254 💬 💬 |
926 | Porphyrin metabolism 💬 5 genes, 4 drugs (DrugBank) and 2 diseases |
GUSB [1] GUSB 💬 |
Vestronidase alfa Vestronidase alfa 💬 |
Vestronidase alfa | 019 [1] 19 💬 💬 |
927 | Porphyrin metabolism 💬 5 genes, 4 drugs (DrugBank) and 2 diseases |
HMOX1 [2] HMOX1, HMOX2 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
928 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
APOC3 [1] APOC3 💬 |
Volanesorsen Volanesorsen 💬 |
Volanesorsen | 265 [1] 265 💬 💬 |
929 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
930 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
931 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬 |
Elafibranor Elafibranor 💬 |
Elafibranor | 093 [2] 93, 94 💬 💬 |
932 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬 💬 |
933 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬 |
Pemafibrate Pemafibrate 💬 |
Pemafibrate | 093 [1] 93 💬 💬 |
934 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬 |
Bocidelpar Bocidelpar 💬 |
Bocidelpar | 113 [1] 113 💬 💬 |
935 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬 |
Leriglitazone Leriglitazone 💬 |
Leriglitazone | 020 [1] 20 💬 💬 |
936 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
937 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 💬 |
938 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬 |
Seladelpar Seladelpar 💬 |
Seladelpar | 093 [2] 93, 94 💬 💬 |
939 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
940 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Alitretinoin Alitretinoin 💬 |
Alitretinoin | 049 [1] 49 💬 💬 |
941 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Bexarotene Bexarotene 💬 |
Bexarotene | 013 [2] 13, 75 💬 💬 |
942 | Primary bile acid biosynthesis 💬 1 gene, 1 drug (DrugBank) and 2 diseases |
CYP46A1 [1] CYP46A1 💬 |
Soticlestat Soticlestat 💬 |
Soticlestat | 140 [2] 140, 144 💬 💬 |
943 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Acalabrutinib Acalabrutinib 💬 |
Acalabrutinib | 046 [2] 46, 61 💬 💬 |
944 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Branebrutinib Branebrutinib 💬 |
Branebrutinib | 046 [3] 46, 49, 53 💬 💬 |
945 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Evobrutinib Evobrutinib 💬 |
Evobrutinib | 013 [3] 13, 46, 49 💬 💬 |
946 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Fenebrutinib Fenebrutinib 💬 |
Fenebrutinib | 013 [1] 13 💬 💬 |
947 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Ibrutinib Ibrutinib 💬 |
Ibrutinib | 028 [3] 28, 60, 61 💬 💬 |
948 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 [4] 13, 49, 61, 63 💬 💬 |
949 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Remibrutinib Remibrutinib 💬 |
Remibrutinib | 013 [2] 13, 53 💬 💬 |
950 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK [1] BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬 💬 |
951 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD19 [1] CD19 💬 |
Inebilizumab Inebilizumab 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 💬 |
952 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD19 [1] CD19 💬 |
Obexelimab Obexelimab 💬 |
Obexelimab | 300 [1] 300 💬 💬 |
953 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD3D [2] CD3D, CD3E 💬 |
Otelixizumab Otelixizumab 💬 |
Otelixizumab | 046 [1] 46 💬 💬 |
954 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD3D [2] CD3D, CD3E 💬 |
Visilizumab Visilizumab 💬 |
Visilizumab | 096 [2] 96, 97 💬 💬 |
955 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD3E [1] CD3E 💬 |
Mosunetuzumab Mosunetuzumab 💬 |
Mosunetuzumab | 049 [1] 49 💬 💬 |
956 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD4 [1] CD4 💬 |
Zanolimumab Zanolimumab 💬 |
Zanolimumab | 046 [1] 46 💬 💬 |
957 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD40 [1] CD40 💬 |
Bleselumab Bleselumab 💬 |
Bleselumab | 222 [1] 222 💬 💬 |
958 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD40 [1] CD40 💬 |
Iscalimab Iscalimab 💬 |
Iscalimab | 049 [2] 49, 53 💬 💬 |
959 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD40 [1] CD40 💬 |
Ravagalimab Ravagalimab 💬 |
Ravagalimab | 053 [2] 53, 97 💬 💬 |
960 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD40LG [1] CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 [1] 63 💬 💬 |
961 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
IL2RG [1] IL2RG 💬 |
Aldesleukin Aldesleukin 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 💬 |
962 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
JAK3 [1] JAK3 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
963 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
JAK3 [1] JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
964 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
965 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
966 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
TNFRSF13C [1] TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 [7] 35, 46, 49, 53, 61, 63, 95 💬 💬 |
967 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Crovalimab Crovalimab 💬 |
Crovalimab | 062 [2] 62, 109 💬 💬 |
968 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Eculizumab Eculizumab 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 💬 |
969 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Nomacopan Nomacopan 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 💬 |
970 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Pozelimab Pozelimab 💬 |
Pozelimab | 011 [2] 11, 62 💬 💬 |
971 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Ravulizumab Ravulizumab 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 💬 |
972 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Vilobelimab Vilobelimab 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 💬 |
973 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬 |
Zilucoplan Zilucoplan 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 💬 |
974 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
975 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
976 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
977 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
978 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
979 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
980 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
981 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
982 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
983 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
984 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
985 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
986 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
987 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
988 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 [2] 6 , 206 💬 💬 |
989 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 💬 |
990 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
991 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 💬 |
992 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
993 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 [1] 8 💬 💬 |
994 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
995 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
996 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [1] IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 [1] 51 💬 💬 |
997 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [2] IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
998 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
999 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
1000 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
1001 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
1002 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
1003 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
1004 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
1005 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
1006 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
1007 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1008 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1009 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1010 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
1011 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 [1] 160 💬 💬 |
1012 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
1013 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
1014 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 [2] 49, 222 💬 💬 |
1015 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PRKCD [1] PRKCD 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 [1] 97 💬 💬 |
1016 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
1017 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PSMB5 [1] PSMB5 💬 |
Carfilzomib Carfilzomib 💬 |
Carfilzomib | 028 [1] 28 💬 💬 |
1018 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PSMB5 [1] PSMB5 💬 |
Ixazomib Ixazomib 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 💬 |
1019 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |
1020 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
1021 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
1022 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
1023 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
1024 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
1025 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
1026 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
1027 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
1028 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
1029 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 [1] 28 💬 💬 |
1030 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 💬 |
1031 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
1032 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 [2] 46, 85 💬 💬 |
1033 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 [2] 34, 65 💬 💬 |
1034 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 💬 |
1035 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1036 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1037 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
1038 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
1039 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
1040 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1041 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1042 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1043 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1044 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1045 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
1046 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
1047 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
1048 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
1049 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
1050 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
1051 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
1052 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
1053 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
1054 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
1055 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
1056 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1057 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1058 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
1059 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Desogestrel Desogestrel 💬 |
Desogestrel | 230 [1] 230 💬 💬 |
1060 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Dydrogesterone Dydrogesterone 💬 |
Dydrogesterone | 013 [1] 13 💬 💬 |
1061 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Levonorgestrel Levonorgestrel 💬 |
Levonorgestrel | 013 [1] 13 💬 💬 |
1062 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬 |
Medroxyprogesterone acetate | 013 [8] 13, 35, 46, 49, 50, 51, 60, 107 💬 💬 |
1063 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Megestrol acetate Megestrol acetate 💬 |
Megestrol acetate | 076 [1] 76 💬 💬 |
1064 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Mifepristone Mifepristone 💬 |
Mifepristone | 075 [1] 75 💬 💬 |
1065 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Nomegestrol Nomegestrol 💬 |
Nomegestrol | 013 [1] 13 💬 💬 |
1066 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Nomegestrol acetate Nomegestrol acetate 💬 |
Nomegestrol acetate | 013 [1] 13 💬 💬 |
1067 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Norethindrone Norethindrone 💬 |
Norethisterone | 013 [4] 13, 46, 49, 299 💬 💬 |
1068 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Norgestimate Norgestimate 💬 |
Norgestimate | 299 [1] 299 💬 💬 |
1069 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Progesterone Progesterone 💬 |
Progesterone | 076 [2] 76, 299 💬 💬 |
1070 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
1071 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1072 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1073 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1074 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PLK1 [1] PLK1 💬 |
Rigosertib Rigosertib 💬 |
Rigosertib | 036 [1] 36 💬 💬 |
1075 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
CYP17A1 [1] CYP17A1 💬 |
Ketoconazole Ketoconazole 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 💬 |
1076 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
CYP17A1 [1] CYP17A1 💬 |
Levoketoconazole Levoketoconazole 💬 |
Levoketoconazole | 075 [1] 75 💬 💬 |
1077 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [1] ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
1078 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [1] ESR1 💬 |
Desogestrel Desogestrel 💬 |
Desogestrel | 230 [1] 230 💬 💬 |
1079 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [1] ESR1 💬 |
Ethinyl estradiol Ethinyl estradiol 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 💬 |
1080 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Clomifene Clomifene 💬 |
Clomifene | 074 [1] 74 💬 💬 |
1081 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
1082 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
1083 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol Estradiol 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 💬 |
1084 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estradiol valerate Estradiol valerate 💬 |
Estradiol valerate | 065 [1] 65 💬 💬 |
1085 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol Estriol 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
1086 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Estriol tripropionate Estriol tripropionate 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
1087 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Fulvestrant Fulvestrant 💬 |
Fulvestrant | 049 [2] 49, 86 💬 💬 |
1088 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Mestranol Mestranol 💬 |
Mestranol | 046 [2] 46, 49 💬 💬 |
1089 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Prasterone Prasterone 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 💬 |
1090 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Raloxifene Raloxifene 💬 |
Raloxifene | 046 [1] 46 💬 💬 |
1091 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬 |
Tamoxifen Tamoxifen 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 💬 |
1092 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 [1] JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
1093 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 [1] JAK2 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 [1] 46 💬 💬 |
1094 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 [1] JAK2 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 💬 |
1095 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 [1] JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
1096 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1097 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1098 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1099 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1100 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1101 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
1102 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
1103 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1104 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1105 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1106 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1107 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PRL [1] PRL 💬 |
Bromocriptine Bromocriptine 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 💬 |
1108 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PRL [1] PRL 💬 |
Cabergoline Cabergoline 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 💬 |
1109 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
PRL [1] PRL 💬 |
Terguride Terguride 💬 |
Terguride | 051 [2] 51, 86 💬 💬 |
1110 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
RAF1 [1] RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1111 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
1112 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
1113 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1114 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1115 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
1116 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
TNFSF11 [1] TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
1117 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
1118 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬 |
Vigabatrin Vigabatrin 💬 |
Vigabatrin | 145 [2] 145, 158 💬 💬 |
1119 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Calusterone Calusterone 💬 |
Calusterone | 002 [1] 2 💬 💬 |
1120 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
1121 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Flutamide Flutamide 💬 |
Flutamide | 081 [1] 81 💬 💬 |
1122 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Nandrolone Nandrolone 💬 |
Nandrolone | 060 [2] 60, 85 💬 💬 |
1123 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Nandrolone decanoate Nandrolone decanoate 💬 |
Nandrolone decanoate | 060 [2] 60, 85 💬 💬 |
1124 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
1125 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Prasterone Prasterone 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 💬 |
1126 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Stanozolol Stanozolol 💬 |
Stanozolol | 060 [1] 60 💬 💬 |
1127 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
1128 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone decanoate Testosterone decanoate 💬 |
Testosterone decanoate | 113 [1] 113 💬 💬 |
1129 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone enanthate Testosterone enanthate 💬 |
Testosterone enanthate | 113 [1] 113 💬 💬 |
1130 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone phenylpropionate Testosterone phenylpropionate 💬 |
Testosterone phenylpropionate | 113 [1] 113 💬 💬 |
1131 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone propionate Testosterone propionate 💬 |
Testosterone propionate | 113 [1] 113 💬 💬 |
1132 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone undecanoate Testosterone undecanoate 💬 |
Testosterone undecanoate | 013 [2] 13, 60 💬 💬 |
1133 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
1134 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1135 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1136 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
CASP9 [1] CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 💬 |
1137 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
1138 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
1139 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
1140 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
1141 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
1142 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
1143 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
1144 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR1 [2] FGFR1, FGFR2 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
1145 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR1 [4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
1146 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR2 [1] FGFR2 💬 |
Palifermin Palifermin 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 💬 |
1147 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
1148 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
1149 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
1150 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 [1] IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
1151 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1152 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1153 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1154 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1155 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1156 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
1157 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
1158 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
1159 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
1160 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
1161 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
1162 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
1163 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1164 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1165 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1166 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1167 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1168 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
1169 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
SRD5A2 [1] SRD5A2 💬 |
Dutasteride Dutasteride 💬 |
Dutasteride | 001 [2] 1 , 2 💬 💬 |
1170 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
SRD5A2 [1] SRD5A2 💬 |
Finasteride Finasteride 💬 |
Finasteride | 006 [1] 6 💬 💬 |
1171 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
1172 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
1173 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
1174 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
PSMB5 [1] PSMB5 💬 |
Carfilzomib Carfilzomib 💬 |
Carfilzomib | 028 [1] 28 💬 💬 |
1175 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
PSMB5 [1] PSMB5 💬 |
Ixazomib Ixazomib 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 💬 |
1176 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
1177 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
1178 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
DPP4 [1] DPP4 💬 |
Saxagliptin Saxagliptin 💬 |
Saxagliptin | 299 [1] 299 💬 💬 |
1179 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
DPP4 [1] DPP4 💬 |
Sitagliptin Sitagliptin 💬 |
Sitagliptin | 006 [4] 6 , 75, 233, 299 💬 💬 |
1180 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
KCNQ1 [1] KCNQ1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
1181 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
KCNQ1 [1] KCNQ1 💬 |
Ezogabine Ezogabine 💬 |
Ezogabine | 002 [2] 2 , 144 💬 💬 |
1182 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
MME [1] MME 💬 |
Sacubitril Sacubitril 💬 |
Sacubitril | 058 [2] 58, 222 💬 💬 |
1183 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
BCL2 [1] BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 [1] 28 💬 💬 |
1184 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
MAP3K5 [1] MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 [1] 86 💬 💬 |
1185 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
NFE2L2 [1] NFE2L2 💬 |
Omaveloxolone Omaveloxolone 💬 |
Omaveloxolone | 018 [1] 18 💬 💬 |
1186 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
1187 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [3] BRAF, KDR, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
1188 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
1189 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
1190 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
1191 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
1192 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
1193 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
1194 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
1195 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Clomifene Clomifene 💬 |
Clomifene | 074 [1] 74 💬 💬 |
1196 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 💬 |
1197 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Desogestrel Desogestrel 💬 |
Desogestrel | 230 [1] 230 💬 💬 |
1198 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
1199 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estetrol Estetrol 💬 |
Estetrol | 053 [1] 53 💬 💬 |
1200 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estradiol Estradiol 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 💬 |
1201 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estradiol valerate Estradiol valerate 💬 |
Estradiol valerate | 065 [1] 65 💬 💬 |
1202 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estriol Estriol 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
1203 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Estriol tripropionate Estriol tripropionate 💬 |
Estriol | 013 [2] 13, 227 💬 💬 |
1204 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Ethinyl estradiol Ethinyl estradiol 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 💬 |
1205 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Fulvestrant Fulvestrant 💬 |
Fulvestrant | 049 [2] 49, 86 💬 💬 |
1206 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Mestranol Mestranol 💬 |
Mestranol | 046 [2] 46, 49 💬 💬 |
1207 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Prasterone Prasterone 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 💬 |
1208 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Raloxifene Raloxifene 💬 |
Raloxifene | 046 [1] 46 💬 💬 |
1209 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬 |
Tamoxifen Tamoxifen 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 💬 |
1210 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [1] FGFR1 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
1211 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
1212 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
1213 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
1214 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
1215 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B [1] IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
1216 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬 |
Axitinib Axitinib 💬 |
Axitinib | 034 [1] 34 💬 💬 |
1217 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬 |
Cediranib Cediranib 💬 |
Cediranib | 034 [1] 34 💬 💬 |
1218 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
1219 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [2] KDR, MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
1220 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
1221 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
1222 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
1223 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
1224 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
1225 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
1226 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
1227 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
1228 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
1229 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
1230 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
1231 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
1232 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
1233 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |
1234 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
Fasudil Fasudil 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 💬 |
1235 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK2 [1] ROCK2 💬 |
Belumosudil Belumosudil 💬 |
Belumosudil | 051 [2] 51, 85 💬 💬 |
1236 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬 |
Taladegib Taladegib 💬 |
Taladegib | 085 [1] 85 💬 💬 |
1237 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬 |
Vismodegib Vismodegib 💬 |
Vismodegib | 085 [1] 85 💬 💬 |
1238 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
1239 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1240 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
1241 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
1242 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TGFB1 [2] TGFB1, TGFB2 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
1243 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
1244 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
1245 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
1246 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
1247 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
1248 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
1249 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
1250 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
1251 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
1252 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
1253 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
1254 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬 |
Aflibercept Aflibercept 💬 |
Aflibercept | 090 [2] 90, 166 💬 💬 |
1255 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬 |
Bevacizumab Bevacizumab 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 💬 |
1256 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬 |
Ranibizumab Ranibizumab 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 💬 |
1257 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digitoxin Digitoxin 💬 |
Digitoxin | 299 [1] 299 💬 💬 |
1258 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
Digoxin Digoxin 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 💬 |
1259 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
CA2 [2] CA2, CA4 💬 |
Acetazolamide Acetazolamide 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬 |
1260 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
CA2 [2] CA2, CA4 💬 |
Dichlorphenamide Dichlorphenamide 💬 |
Diclofenamide | 114 [1] 114 💬 💬 |
1261 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
CA2 [2] CA2, CA4 💬 |
Dorzolamide Dorzolamide 💬 |
Dorzolamide | 090 [1] 90 💬 💬 |
1262 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
1263 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
1264 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
1265 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
GUCY2C [1] GUCY2C 💬 |
Linaclotide Linaclotide 💬 |
Linaclotide | 006 [2] 6 , 97 💬 💬 |
1266 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
1267 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
1268 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
1269 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mizoribine Mizoribine 💬 |
Mizoribine | 046 [8] 46, 49, 51, 53, 66, 94, 222, 224 💬 💬 |
1270 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬 |
1271 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
1272 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
NPR1 [1] NPR1 💬 |
Nesiritide Nesiritide 💬 |
Nesiritide | 046 [2] 46, 58 💬 💬 |
1273 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
NPR1 [2] NPR1, NPR2 💬 |
Erythrityl tetranitrate Erythrityl tetranitrate 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 💬 |
1274 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
NPR2 [1] NPR2 💬 |
Vosoritide Vosoritide 💬 |
Vosoritide | 276 [1] 276 💬 💬 |
1275 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
1276 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
1277 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
1278 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1279 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
1280 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
1281 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
1282 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
1283 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
1284 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
1285 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
1286 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
1287 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
1288 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
1289 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [2] PDE4A, PDE5A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
1290 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
1291 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
1292 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
1293 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬 |
Udenafil Udenafil 💬 |
Udenafil | 086 [2] 86, 210 💬 💬 |
1294 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬 |
Vardenafil Vardenafil 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 💬 |
1295 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM1 [1] RRM1 💬 |
Cladribine Cladribine 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 💬 |
1296 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM1 [1] RRM1 💬 |
Clofarabine Clofarabine 💬 |
Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬 💬 |
1297 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM1 [1] RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
1298 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
1299 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
1300 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
XDH [1] XDH 💬 |
Febuxostat Febuxostat 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 💬 |
1301 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
DHODH [1] DHODH 💬 |
Leflunomide Leflunomide 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 💬 |
1302 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
DHODH [1] DHODH 💬 |
Teriflunomide Teriflunomide 💬 |
Teriflunomide | 013 [3] 13, 25, 26 💬 💬 |
1303 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM1 [1] RRM1 💬 |
Cladribine Cladribine 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 💬 |
1304 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM1 [1] RRM1 💬 |
Clofarabine Clofarabine 💬 |
Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬 💬 |
1305 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM1 [1] RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
1306 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
1307 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
TYMS [1] TYMS 💬 |
Tegafur Tegafur 💬 |
Tegafur | 046 [1] 46 💬 💬 |
1308 | Pyruvate metabolism 💬 3 genes, 1 drug (DrugBank) and 1 disease |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
Fomepizole Fomepizole 💬 |
Fomepizole | 301 [1] 301 💬 💬 |