Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 24 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
CPS1 [1] CPS1 💬Alanine, aspartate and glutamate metabolism
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Carglumic acid Carglumic acid 💬Alanine, aspartate and glutamate metabolism
| Carglumic acid | 245 [3] 245, 246, 251 💬
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| 2 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A [1] PDE2A 💬Aldosterone synthesis and secretion
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Bucladesine Bucladesine 💬Aldosterone synthesis and secretion
| Bucladesine | 246 [1] 246 💬2. Aldosterone synthesis and secretion
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| 3 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬Apelin signaling pathway
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Bucladesine Bucladesine 💬Apelin signaling pathway
| Bucladesine | 246 [1] 246 💬3. Apelin signaling pathway
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| 4 | Arginine biosynthesis 💬 1 gene, 1 drug (DrugBank) and 3 diseases |
CPS1 [1] CPS1 💬Arginine biosynthesis
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Carglumic acid Carglumic acid 💬Arginine biosynthesis
| Carglumic acid | 245 [3] 245, 246, 251 💬
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| 5 | Biosynthesis of amino acids 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬Arginine biosynthesis
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Carglumic acid Carglumic acid 💬Biosynthesis of amino acids
| Carglumic acid | 245 [3] 245, 246, 251 💬
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| 6 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬
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Bucladesine Bucladesine 💬Calcium signaling pathway
| Bucladesine | 246 [1] 246 💬6. Calcium signaling pathway
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| 7 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
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Bucladesine Bucladesine 💬cAMP signaling pathway
| Bucladesine | 246 [1] 246 💬7. cAMP signaling pathway
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| 8 | Carbon metabolism 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬Carbon metabolism
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Carglumic acid Carglumic acid 💬Carbon metabolism
| Carglumic acid | 245 [3] 245, 246, 251 💬
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| 9 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬
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Bucladesine Bucladesine 💬cGMP-PKG signaling pathway
| Bucladesine | 246 [1] 246 💬9. cGMP-PKG signaling pathway
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| 10 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬
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Bucladesine Bucladesine 💬Cortisol synthesis and secretion
| Bucladesine | 246 [1] 246 💬10. Cortisol synthesis and secretion
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