Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 45 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬Alcoholism
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Chlorpromazine Chlorpromazine 💬Alcoholism
| Chlorpromazine | 254 [1] 254 💬1. Alcoholism
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| 2 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬
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Chlorpromazine Chlorpromazine 💬Alzheimer disease
| Chlorpromazine | 254 [1] 254 💬2. Alzheimer disease
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| 3 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
ALAS1 [1] ALAS1 💬Biosynthesis of cofactors
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Givosiran Givosiran 💬Biosynthesis of cofactors
| Givosiran | 254 [1] 254 💬3. Biosynthesis of cofactors
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| 4 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
ALAS1 [2] ALAS1, ALAS2 💬
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Hemin Hemin 💬Biosynthesis of cofactors
| Hemin | 254 [1] 254 💬4. Biosynthesis of cofactors
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| 5 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬Calcium signaling pathway |
Chlorpromazine Chlorpromazine 💬Calcium signaling pathway
| Chlorpromazine | 254 [1] 254 💬5. Calcium signaling pathway
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| 6 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬Calcium signaling pathway
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Cimetidine Cimetidine 💬Calcium signaling pathway
| Cimetidine | 002 [2] 2 , 254 💬
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| 7 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬
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Chlorpromazine Chlorpromazine 💬cAMP signaling pathway
| Chlorpromazine | 254 [1] 254 💬7. cAMP signaling pathway
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| 8 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
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Chlorpromazine Chlorpromazine 💬cGMP-PKG signaling pathway
| Chlorpromazine | 254 [1] 254 💬8. cGMP-PKG signaling pathway
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| 9 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
HMOX1 [1] HMOX1 💬Chemical carcinogenesis - reactive oxygen species
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Stannsoporfin Stannsoporfin 💬Chemical carcinogenesis - reactive oxygen species
| Stannsoporfin | 254 [1] 254 💬9. Chemical carcinogenesis - reactive oxygen species
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| 10 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
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Chlorpromazine Chlorpromazine 💬Cholinergic synapse
| Chlorpromazine | 254 [1] 254 💬10. Cholinergic synapse
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