Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 26 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR1 [1] FGFR1 💬Adherens junction
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Infigratinib Infigratinib 💬Adherens junction
| Infigratinib | 276 [1] 276 💬1. Adherens junction
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| 2 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
FGFR3 [1] FGFR3 💬Bladder cancer
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Infigratinib Infigratinib 💬Bladder cancer
| Infigratinib | 276 [1] 276 💬2. Bladder cancer
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| 3 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FGFR1 [1] FGFR1 💬Breast cancer
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Infigratinib Infigratinib 💬Breast cancer
| Infigratinib | 276 [1] 276 💬3. Breast cancer
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| 4 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
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Infigratinib Infigratinib 💬Calcium signaling pathway
| Infigratinib | 276 [1] 276 💬4. Calcium signaling pathway
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| 5 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
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Infigratinib Infigratinib 💬Central carbon metabolism in cancer
| Infigratinib | 276 [1] 276 💬5. Central carbon metabolism in cancer
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| 6 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
NPR2 [1] NPR2 💬cGMP-PKG signaling pathway
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Vosoritide Vosoritide 💬cGMP-PKG signaling pathway
| Vosoritide | 276 [1] 276 💬6. cGMP-PKG signaling pathway
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| 7 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 [2] FGFR2, FGFR3 💬
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Infigratinib Infigratinib 💬EGFR tyrosine kinase inhibitor resistance
| Infigratinib | 276 [1] 276 💬7. EGFR tyrosine kinase inhibitor resistance
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| 8 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
FGFR2 [2] FGFR2, FGFR3 💬
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Infigratinib Infigratinib 💬Endocytosis
| Infigratinib | 276 [1] 276 💬8. Endocytosis
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| 9 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
FGFR2 [1] FGFR2 💬Gastric cancer
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Infigratinib Infigratinib 💬Gastric cancer
| Infigratinib | 276 [1] 276 💬9. Gastric cancer
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| 10 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
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Infigratinib Infigratinib 💬MAPK signaling pathway
| Infigratinib | 276 [1] 276 💬10. MAPK signaling pathway
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