Gene

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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] BRAF 💬	Dabrafenib 💬	Dabrafenib	[1] 34 💬 💬
2	Acute myeloid leukemia 💬	[4] BRAF, FLT3, KIT, RAF1 💬	Sorafenib 💬	Sorafenib	[2] 34, 86 💬 💬
3	Acute myeloid leukemia 💬	[3] CSF1R, FLT3, KIT 💬	Pexidartinib 💬	Pexidartinib	[1] 34 💬 💬
4	Acute myeloid leukemia 💬	[3] CSF1R, FLT3, KIT 💬	Sunitinib 💬	Sunitinib	[2] 28, 34 💬 💬
5	Acute myeloid leukemia 💬	[1] CSF2 💬	Otilimab 💬	Otilimab	[1] 46 💬 💬
6	Acute myeloid leukemia 💬	[1] KIT 💬	Dasatinib 💬	Dasatinib	[2] 51, 85 💬 💬
7	Acute myeloid leukemia 💬	[1] KIT 💬	Dasatinib 💬	Dasatinib	[2] 51, 85 💬 💬
8	Acute myeloid leukemia 💬	[1] KIT 💬	Imatinib 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
9	Acute myeloid leukemia 💬	[1] KIT 💬	Masitinib 💬	Masitinib	[6] 2 , 5 , 6 , 13, 46, 96 💬 💬
10	Acute myeloid leukemia 💬	[1] KIT 💬	Nilotinib 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬 💬
11	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	Binimetinib 💬	Binimetinib	[1] 34 💬 💬
12	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	Cobimetinib 💬	Cobimetinib	[1] 280 💬 💬
13	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	Mirdametinib 💬	Mirdametinib	[1] 34 💬 💬
14	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	Selumetinib 💬	Selumetinib	[1] 34 💬 💬
15	Acute myeloid leukemia 💬	[2] MAP2K1, MAP2K2 💬	Trametinib 💬	Trametinib	[4] 2 , 34, 279, 280 💬 💬
16	Acute myeloid leukemia 💬	[1] MPO 💬	Verdiperstat 💬	Verdiperstat	[3] 2 , 17, 127 💬 💬
17	Acute myeloid leukemia 💬	[1] MTOR 💬	Everolimus 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
18	Acute myeloid leukemia 💬	[1] MTOR 💬	Sirolimus 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
19	Acute myeloid leukemia 💬	[1] MTOR 💬	Temsirolimus 💬	Temsirolimus	[1] 13 💬 💬
20	Acute myeloid leukemia 💬	[1] NFKB1 💬	Iguratimod 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬 💬
21	Acute myeloid leukemia 💬	[1] PIK3CA 💬	Alpelisib 💬	Alpelisib	[1] 138 💬 💬
22	Acute myeloid leukemia 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	Leniolisib 💬	Leniolisib	[2] 53, 65 💬 💬
23	Acute myeloid leukemia 💬	[1] PIK3CD 💬	Parsaclisib 💬	Parsaclisib	[3] 35, 53, 61 💬 💬
24	Acute myeloid leukemia 💬	[2] PML, RARA 💬	Tretinoin 💬	Tretinoin	[6] 2 , 62, 63, 75, 94, 231 💬 💬
25	Acute myeloid leukemia 💬	[1] RARA 💬	Acitretin 💬	Acitretin	[1] 37 💬 💬
26	Acute myeloid leukemia 💬	[1] RARA 💬	Alitretinoin 💬	Alitretinoin	[1] 49 💬 💬
27	Acute myeloid leukemia 💬	[1] RARA 💬	Fenretinide 💬	Fenretinide	[1] 299 💬 💬
28	Acute myeloid leukemia 💬	[1] RARA 💬	Isotretinoin 💬	Isotretinoin	[4] 36, 39, 159, 160 💬 💬
29	Acute myeloid leukemia 💬	[1] RARA 💬	Tamibarotene 💬	Tamibarotene	[2] 26, 96 💬 💬
30	Acute myeloid leukemia 💬	[1] RARA 💬	Vitamin A 💬	Vitamin A	[3] 13, 53, 90 💬 💬
31	Acute myeloid leukemia 💬	[1] RELA 💬	Edasalonexent 💬	Edasalonexent	[1] 113 💬 💬