Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 2 , 67 💬

2

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 51, 85 💬

3

Chronic myeloid leukemia 💬

[1] ABL1 💬

[2] 51, 85 💬

4

Chronic myeloid leukemia 💬

[1] ABL1 💬

[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
35	Pemphigus;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
86	Pulmonary arterial hypertension;PAH;
87	Pulmonary veno-occlusive disease;Pulmonary capillary hemangiomatosis;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
89	Lymphangioleiomyomatosis;LAM;
162	Pemphigoid;

5

Chronic myeloid leukemia 💬

[1] ABL1 💬

[5] 6 , 8 , 34, 51, 86 💬

6

Chronic myeloid leukemia 💬

[1] ABL1 💬

Saracatinib 💬

[3] 6 , 89, 272 💬

7

Chronic myeloid leukemia 💬

[1] BRAF 💬

Dabrafenib 💬

[1] 34 💬

8

Chronic myeloid leukemia 💬

[2] BRAF, RAF1 💬

[2] 34, 86 💬

9

Chronic myeloid leukemia 💬

[2] CDK4, CDK6 💬

Abemaciclib 💬

[1] 34 💬

10

Chronic myeloid leukemia 💬

[2] HDAC1, HDAC2 💬

Vorinostat 💬

[2] 75, 96 💬

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