Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Endocrine and other factor-regulated calcium reabsorption 💬

[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬

Name	Full Name
ATP1A1	ATPase Na+/K+ transporting subunit alpha 1
ATP1A2	ATPase Na+/K+ transporting subunit alpha 2
ATP1A3	ATPase Na+/K+ transporting subunit alpha 3
ATP1A4	ATPase Na+/K+ transporting subunit alpha 4

[1] 299 💬

2

Endocrine and other factor-regulated calcium reabsorption 💬

[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬

Name	Full Name
ATP1A1	ATPase Na+/K+ transporting subunit alpha 1
ATP1A2	ATPase Na+/K+ transporting subunit alpha 2
ATP1A3	ATPase Na+/K+ transporting subunit alpha 3
ATP1A4	ATPase Na+/K+ transporting subunit alpha 4

[3] 8 , 46, 210 💬

Disease ID	Name
8	Huntington disease;Huntington chorea;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;

3

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

[1] 74 💬

4

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

[5] 60, 63, 64, 65, 285 💬

5

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

Desogestrel 💬

[1] 230 💬

6

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

[1] 53 💬

7

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

[1] 53 💬

8

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

Name	Other Names
Estradiol	Estradiol (JAN/USP/INN) Climara (TN) Divigel (TN) Estrace (TN) Estraderm (TN) Estrasorb (TN) Estring (TN) Estrogel (TN) Innofem (TN) Vagifem (TN) Vivelle (TN) IMVEXXY MENOSTAR MINIVELLE VIVELLE-DOT DOTTI ESTRADIOL TRANSDERMAL SYSTEM ESTRADIOL VAGINAL ESTRADIOL VAGINAL CREAM LYLLANA YUVAFEM

[7] 13, 46, 49, 65, 76, 226, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
65	Primary immunodeficiency;
76	Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
299	Cystic fibrosis;

9

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

Estradiol valerate 💬

Estradiol valerate

[1] 65 💬

10

Endocrine and other factor-regulated calcium reabsorption 💬

[1] ESR1 💬

[2] 13, 227 💬

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