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KEGG PATHWAY
On map,
Yellow:
Drug target,
Red:
All disease-related
KEGG GENES
KEGG DRUG
DrugBank
Disease ID
1
Ubiquitin mediated proteolysis
💬
2 genes, 2 drugs (DrugBank) and 11 diseases
KEAP1
[1]
KEAP1
💬
Ubiquitin mediated proteolysis
×
Name
Full Name
KEAP1
kelch like ECH associated protein 1
Dimethyl fumarate
Dimethyl fumarate
💬
Ubiquitin mediated proteolysis
×
Name
Other Names
Dimethyl fumarate
Dimethyl fumarate (JAN/USAN)
Tecfidera (TN)
Dimethyl fumarate
013
[5]
13
,
49
,
51
,
86
,
296
💬
1.
Ubiquitin mediated proteolysis
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica;
49
Systemic lupus erythematosus;SLE;
51
Scleroderma;Systemic sclerosis;SSc;
86
Pulmonary arterial hypertension;PAH;
296
Biliary atresia;
2
Ubiquitin mediated proteolysis
💬
2 genes, 2 drugs (DrugBank) and 11 diseases
PML
[1]
PML
💬
Ubiquitin mediated proteolysis
×
Name
Full Name
PML
PML nuclear body scaffold
Tretinoin
Tretinoin
💬
Ubiquitin mediated proteolysis
×
Name
Other Names
Tretinoin
Tretinoin (JAN/USP/INN)
Avita (TN)
Renova (TN)
Retin A (TN)
Tretinoin (TN)
ALTRENO
ATRALIN
RETIN-A
RETIN-A MICRO
TRETINOIN CREAM
Tretinoin
002
[6]
2
,
62
,
63
,
75
,
94
,
231
💬
2.
Ubiquitin mediated proteolysis
×
Disease ID
Name
2
Amyotrophic lateral sclerosis;ALS;
62
Paroxysmal nocturnal hemoglobinuria;PNH;
63
Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;
75
Cushing disease;Cushing;
94
Primary sclerosing cholangitis;PSC;
231
Alpha-1-antitrypsin deficiency;AATD;