Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Carvedilol 💬

[4] 57, 86, 113, 210 💬

Disease ID	Name
57	Idiopathic dilated cardiomyopathy;
86	Pulmonary arterial hypertension;PAH;
113	Muscular dystrophy;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;

2

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Dipivefrin 💬

[1] 6 💬

3

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

[5] 5 , 6 , 17, 169, 170 💬

4

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

[1] 11 💬

5

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Epinephrine 💬

Name	Other Names
Epinephrine	Epinephrine (USP/INN) Adrenaline (JP18) Adrenalin (TN) Auvi-q (TN) Epipen (TN) ADRENALIN(R) CERTA DOSE EPINEPHRINE CONVENIENCE KIT EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL EPINEPHRINE PROFESSIONAL EMS EPINEPHRINESNAP-EMS EPINEPHRINESNAP-V SYMJEPI

[3] 46, 70, 96 💬

6

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Noradrenaline 💬

[2] 22, 296 💬

7

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Pseudoephedrine 💬

Pseudoephedrine

[1] 17 💬

8

Adrenergic signaling in cardiomyocytes 💬

[2] ADRB1, ADRB2 💬

[1] 6 💬

9

Adrenergic signaling in cardiomyocytes 💬

[2] ADRB1, ADRB2 💬

Propranolol 💬

[6] 6 , 158, 167, 227, 278, 296 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
158	Tuberous sclerosis;Tuberous sclerosis complex;
167	Marfan syndrome;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
278	Huge lymphatic malformation with cervicofacial lesion;Huge lymphatic malformation;Lymphatic malformation;
296	Biliary atresia;

10

Adrenergic signaling in cardiomyocytes 💬

[2] ADRB1, ADRB2 💬

[2] 157, 227 💬

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