Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Neuroactive ligand-receptor interaction 💬

[1] CALCA 💬

Fremanezumab 💬

[2] 124, 226 💬

Disease ID	Name
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

2

Vascular smooth muscle contraction 💬

[1] CALCA 💬

Fremanezumab 💬

[2] 124, 226 💬

Disease ID	Name
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

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