Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Allograft rejection 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Allograft rejection 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
3 Autoimmune thyroid disease 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
4 Autoimmune thyroid disease 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
5 Cell adhesion molecules 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6 Cell adhesion molecules 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
7 Graft-versus-host disease 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
8 Graft-versus-host disease 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
9 Intestinal immune network for IgA production 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
10 Intestinal immune network for IgA production 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
11 Rheumatoid arthritis 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
12 Rheumatoid arthritis 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
13 Systemic lupus erythematosus 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
14 Systemic lupus erythematosus 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
15 Toll-like receptor signaling pathway 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
16 Toll-like receptor signaling pathway 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
17 Type I diabetes mellitus 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
18 Type I diabetes mellitus 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
19 Viral myocarditis 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
20 Viral myocarditis 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬
21 Virion - Adenovirus 💬
[2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
22 Virion - Adenovirus 💬
[2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬