Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chemical carcinogenesis - receptor activation 💬
 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 Nicotine 💬 Nicotine [3]  6 , 13, 84 💬
2 Chemical carcinogenesis - receptor activation 💬
 [2] CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline [3]  6 , 18, 53 💬
3 Cholinergic synapse 💬
 [6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 Nicotine 💬 Nicotine [3]  6 , 13, 84 💬
4 Cholinergic synapse 💬
 [2] CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline [3]  6 , 18, 53 💬
5 Neuroactive ligand-receptor interaction 💬
 [16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬 Nicotine 💬 Nicotine [3]  6 , 13, 84 💬
6 Neuroactive ligand-receptor interaction 💬
 [2] CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline [3]  6 , 18, 53 💬
7 Nicotine addiction 💬
 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 Nicotine 💬 Nicotine [3]  6 , 13, 84 💬
8 Nicotine addiction 💬
 [2] CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline [3]  6 , 18, 53 💬

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