Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Cytokine-cytokine receptor interaction 💬

[1] CSF2RA 💬

Mavrilimumab 💬

[2] 41, 46 💬

2

Cytokine-cytokine receptor interaction 💬

[1] CSF2RA 💬

Molgramostim 💬

[3] 97, 229, 299 💬

Disease ID	Name
97	Ulcerative colitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
299	Cystic fibrosis;

3

Cytokine-cytokine receptor interaction 💬

[1] CSF2RA 💬

Regramostim 💬

[1] 229 💬

4

Cytokine-cytokine receptor interaction 💬

[1] CSF2RA 💬

Sargramostim 💬

[7] 6 , 28, 60, 62, 96, 229, 285 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
28	Systemic amyloidosis;AL amyloidosis;
60	Aplastic anemia;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
96	Crohn disease;Terminal ileitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
285	Fanconi anemia;

5

Hematopoietic cell lineage 💬

[1] CSF2RA 💬

Mavrilimumab 💬

[2] 41, 46 💬

6

Hematopoietic cell lineage 💬

[1] CSF2RA 💬

Molgramostim 💬

[3] 97, 229, 299 💬

Disease ID	Name
97	Ulcerative colitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
299	Cystic fibrosis;

7

Hematopoietic cell lineage 💬

[1] CSF2RA 💬

Regramostim 💬

[1] 229 💬

8

Hematopoietic cell lineage 💬

[1] CSF2RA 💬

Sargramostim 💬

[7] 6 , 28, 60, 62, 96, 229, 285 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
28	Systemic amyloidosis;AL amyloidosis;
60	Aplastic anemia;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
96	Crohn disease;Terminal ileitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
285	Fanconi anemia;

9

JAK-STAT signaling pathway 💬

[1] CSF2RA 💬

Mavrilimumab 💬

[2] 41, 46 💬

10

JAK-STAT signaling pathway 💬

[1] CSF2RA 💬

Molgramostim 💬

[3] 97, 229, 299 💬

Disease ID	Name
97	Ulcerative colitis;
229	Autoimmune pulmonary alveolar proteinosis;Congenital pulmonary alveolar proteinosis;Hereditary pulmonary alveolar proteinosis;Pulmonary alveolar proteinosis;PAP;
299	Cystic fibrosis;

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