Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Cortisol synthesis and secretion 💬
 [3] CYP11A1, CYP11B1, CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
2 Cortisol synthesis and secretion 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬
3 Cushing syndrome 💬
 [3] CYP11A1, CYP11B1, CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
4 Cushing syndrome 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬
5 Metabolic pathways 💬
 [3] CYP11A1, CYP11B1, CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
6 Metabolic pathways 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬
7 Ovarian steroidogenesis 💬
 [2] CYP11A1, CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
8 Ovarian steroidogenesis 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬
9 Prolactin signaling pathway 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬
10 Prolactin signaling pathway 💬
 [1] CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
11 Steroid hormone biosynthesis 💬
 [3] CYP11A1, CYP11B1, CYP17A1 💬 Levoketoconazole 💬 Levoketoconazole [1] 75 💬
12 Steroid hormone biosynthesis 💬
 [1] CYP17A1 💬 Ketoconazole 💬 Ketoconazole [3]  8 , 13, 75 💬

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