Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
2 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
3 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
4 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
5 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
6 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
7 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
8 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
9 Dopaminergic synapse 💬
[1] DRD4 💬 Clozapine 💬 Clozapine [1]  6  💬
10 Neuroactive ligand-receptor interaction 💬
[11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
11 Neuroactive ligand-receptor interaction 💬
[6] ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
12 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
13 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
14 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
15 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
16 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
17 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
18 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬